Hospital‑acquired pneumonia caused by <em>Kodamaea ohmeri</em> during extracorporeal membrane oxygenation treatment: A case report and literature review

Ding,Tao; Zhu,Yi; Zhang,Zhong-Man; Zou,Yue; An,Di; Li,Wei; Chen,Xu-Feng

doi:10.3892/etm.2023.12331

Hospital‑acquired pneumonia caused by Kodamaea ohmeri during extracorporeal membrane oxygenation treatment: A case report and literature review

Authors:
- Tao Ding
- Yi Zhu
- Zhong-Man Zhang
- Yue Zou
- Di An
- Wei Li
- Xu-Feng Chen
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Affiliations: Emergency Department, The First Affiliated Hospital of Nanjing Medical University and Jiangsu Province Hospital, Nanjing, Jiangsu 210029, P.R. China
Published online on: November 30, 2023 https://doi.org/10.3892/etm.2023.12331
Article Number: 43

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Abstract

Kodamaea ohmeri (K. ohmeri) is an ascosporogenic species of yeast that belongs to the genus Ascosporogenous and the family of Saccharomycetaceae. It has recently been found to cause various types of infections, particularly in critically ill immunocompromised patients. The present study describes a case of hospital‑acquired pneumonia caused by K. ohmeri during veno‑arterial extracorporeal membrane oxygenation. The fungal culture turned negative after the administration of caspofungin and amphotericin B. Extracorporeal membrane oxygenation (ECMO) is an adjunctive medical technique that provides temporary cardiopulmonary support for patients. Previous observations have suggested that the immune function of patients will typically decline during the use of ECMO, rendering infection to be one of the main complications of ECMO. K. ohmeri is a rare pathogenic fungus, particularly in immunocompromised individuals with vascular catheters, while amphotericin B is the most common antifungal therapy administered to treat K. ohmeri infections. It is important to raise awareness of rare fungal infections and actively treat them.

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