Open Access

Rare features of giant cell tumors of the bone: A case report

  • Authors:
    • Chao Wang
    • Ying Guo
    • Lu Wang
    • Zunzhen Nie
    • Jin Zhu
    • Qingguo Yan
  • View Affiliations

  • Published online on: August 28, 2024     https://doi.org/10.3892/etm.2024.12698
  • Article Number: 409
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Giant cell tumors of the bone are local invasive diseases that are mainly composed of neoplastic monocytes and nonneoplastic multinucleated giant cells, mostly in the long bones of patients with mature bones. A specific H3F3A mutation is the key to its diagnosis. The present paper reports a case of giant cell tumor of the bone (GCTB) characterized by diffuse cholesterol crystals with few multinucleated giant cells. Imaging examination combined with immunohistochemical H3.3 G34W positivity was used to diagnose the patient with GCTB. Understanding the unique histological morphology of this patient will help doctors correctly diagnose giant cell tumors of bone and avoid misdiagnosis.
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November-2024
Volume 28 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Wang C, Guo Y, Wang L, Nie Z, Zhu J and Yan Q: Rare features of giant cell tumors of the bone: A case report. Exp Ther Med 28: 409, 2024.
APA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., & Yan, Q. (2024). Rare features of giant cell tumors of the bone: A case report. Experimental and Therapeutic Medicine, 28, 409. https://doi.org/10.3892/etm.2024.12698
MLA
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 409.
Chicago
Wang, C., Guo, Y., Wang, L., Nie, Z., Zhu, J., Yan, Q."Rare features of giant cell tumors of the bone: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 409. https://doi.org/10.3892/etm.2024.12698