J VijgJY WeiUnderstanding the biology of aging: the key to prevention and therapyJ Am Geriatr Soc4342643419957706635

T FlattPS SchmidtIntegrating evolutionary and molecular genetics of agingBiochim Biophys Acta1790951962200910.1016/j.bbagen.2009.07.01019619612

TB KirkwoodSN AustadWhy do we age?Nature408233238200010.1038/3504168211089980

TB KirkwoodS MelovOn the programmed/non-programmed nature of ageing within the life historyCurr Biol21R701R707201110.1016/j.cub.2011.07.02021959160

GS LynchSarcopenia - Age-Related Muscle Wasting and Weakness: Mechanisms and TreatmentsSpringerNew York480201110.1007/978-90-481-9713-2

LV ThompsonAge-related muscle dysfunctionExp Gerontol44106111200910.1016/j.exger.2008.05.00318657920

WJ EvansSkeletal muscle loss: cachexia, sarcopenia, and inactivityAm J Clin Nutr911123S1127S201010.3945/ajcn.2010.28608A20164314

DR ThomasSarcopeniaClin Geriatr Med26331346201010.1016/j.cger.2010.02.012

MJ BergerTJ DohertySarcopenia: prevalence, mechanisms, and functional consequencesInterdiscip Top Gerontol3794114201010.1159/00031999720703058

GB ForbesJC ReinaAdult lean body mass declines with age: some longitudinal observationsMetabolism19653663197010.1016/0026-0495(70)90062-45459997

RN BaumgartnerPM StauberD McHughKM KoehlerPJ GarryCross-sectional age differences in body composition in persons 60⁺ years of ageJ Gerontol A Biol Sci Med Sci50M307M31619957583802

RS LindleEJ MetterNA LynchJL FlegJL FozardJ TobinTA RoyBF HurleyAge and gender comparisons of muscle strength in 654 women and men aged 20–93 yrJ Appl Physiol831581158719979375323

RN BaumgartnerKM KoehlerD GallagherL RomeroSB HeymsfieldRR RossPJ GarryRD LindemanEpidemiology of sarcopenia among the elderly in New MexicoAm J Epidemiol147755763199810.1093/oxfordjournals.aje.a0095209554417

LJ Melton IIIS KhoslaCS CrowsonMK O’ConnorWM O’FallonBL RiggsEpidemiology of sarcopeniaJ Am Geriatr Soc486256302000

I JanssenSB HeymsfieldR RossLow relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disabilityJ Am Geriatr Soc50889896200210.1046/j.1532-5415.2002.50216.x12028177

BH GoodpasterSW ParkTB HarrisSB KritchevskyM NevittAV SchwartzEM SimonsickFA TylavskyM VisserAB NewmanThe loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition studyJ Gerontol A Biol Sci Med Sci6110591064200610.1093/gerona/61.10.105917077199

MJ DelmonicoTB HarrisM VisserSW ParkMB ConroyP Velasquez-MieyerR BoudreauTM ManiniM NevittAB NewmanBH GoodpasterHealth, aging, and body. Longitudinal study of muscle strength, quality, and adipose tissue infiltrationAm J Clin Nutr9015791585200910.3945/ajcn.2009.2804719864405

KK HedayatiM DittmarPrevalence of sarcopenia among older community-dwelling people with normal health and nutritional stateEcol Food Nutr49110128201010.1080/0367024090354115421883084

HP PatelHE SyddallHJ MartinCE StewartC CooperAA SayerHertfordshire sarcopenia study: design and methodsBMC Geriatr1043201010.1186/1471-2318-10-4320587018

DN ProctorPC O’BrienEJ AtkinsonKS NairComparison of techniques to estimate total body skeletal muscle mass in people of different age groupsAm J Physiol277E489E495199910484361

AA VandervoortAging of the human neuromuscular systemMuscle Nerve251725200210.1002/mus.121511754180

WR FronteraKF ReidEM PhillipsLS KrivickasVA HughesR RoubenoffFA FieldingMuscle fiber size and function in elderly humans: a longitudinal studyJ Appl Physiol105637642200810.1152/japplphysiol.90332.200818556434

JA FaulknerLM LarkinDR ClaflinSV BrooksAge-related changes in the structure and function of skeletal musclesClin Exp Pharmacol Physiol3410911096200710.1111/j.1440-1681.2007.04752.x17880359

D ScottL BlizzardJ FellG JonesThe epidemiology of sarcopenia in community living older adults: what role does lifestyle play?J Cachexia Sarcopenia Muscle2125134201110.1007/s13539-011-0036-421966639

RH CokerRR WolfeBedrest and sarcopeniaCurr Opin Clin Nutr Metab Care15711201210.1097/MCO.0b013e32834da629

P AagaardC SuettaP CaserottiSP MagnussonM KjaerRole of the nervous system in sarcopenia and muscle atrophy with aging: strength training as a countermeasureScand J Med Sci Sports204964201010.1111/j.1600-0838.2009.01084.x20487503

E EdstromM AltunE BergmanH JohnsonS KullbergV Ramirez-LeonB UlfhakeFactors contributing to neuromuscular impairment and sarcopenia during agingPhysiol Behav92129135200710.1016/j.physbeh.2007.05.04017585972

I BeyerT MetsI BautmansChronic low-grade inflammation and age-related sarcopeniaCurr Opin Clin Nutr Metab Care151222201210.1097/MCO.0b013e32834dd29722108098

L LarssonB SjodinJ KarlssonHistochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22–65 yearsActa Physiol Scand10331391978208350

M MuscaritoliSD AnkerJ ArgilésZ AversaJM BauerG BioloY BoirieI BosaeusT CederholmP CostelliConsensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) ‘cachexia-anorexia in chronic wasting diseases’ and ‘nutrition in geriatrics’Clin Nutr29154159201020060626

AJ Cruz-JentoftJP BaeyensJM BauerY BoirieT CederholmF LandiFC MartinJP MichelY RollandSM SchneiderSarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older PeopleAge Ageing39412423201010.1093/ageing/afq03420392703

AJ Cruz-JentoftF LandiE TopinkovaJP MichelUnderstanding sarcopenia as a geriatric syndromeCurr Opin Clin Nutr Metab Care1317201010.1097/MCO.0b013e328333c1c119915458

H PatelHE SyddallHJ MartinC CooperC StewartAA SayerThe feasibility and acceptability of muscle biopsy in epidemiological studies: findings from the Hertfordshire Sarcopenia Study (HSS)J Nutr Health Aging151015201110.1007/s12603-011-0006-821267515

J LexellCC TaylorM SjostromWhat is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old menJ Neurol Sci8427529419883379447

J LexellHuman aging, muscle mass, and fiber type compositionJ Gerontol A Biol Sci Med Sci5011161995

C LewisP DoranK OhlendieckProteomic analysis of dystrophic muscleMethods Mol Biol798357369201210.1007/978-1-61779-343-1_2022130847

K OhlendieckProteomics of skeletal muscle differentiation, neuromuscular disorders and fiber agingExpert Rev Proteomics7283296201010.1586/epr.10.220377394

C GelfiM VassoP CerretelliDiversity of human skeletal muscle in health and disease: contribution of proteomicsJ Proteomics74774795201110.1016/j.jprot.2011.02.02821414428

K OhlendieckSkeletal muscle proteomics: current approaches, technical challenges and emerging techniquesSkelet Muscle16201110.1186/2044-5040-1-621798084

P DoranP DonoghueK O’ConnellJ GannonK OhlendieckProteomics of skeletal muscle agingProteomics99891003200910.1002/pmic.20080036519180535

I PiecA ListratJ AlliotC ChambonRG TaylorD BechetDifferential proteome analysis of aging in rat skeletal muscleFASEB J1911431145200515831715

K O’ConnellJ GannonP DoranK OhlendieckProteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscleInt J Mol Med20145153200717611631

D DoranJ GannonK O’ConnellK OhlendieckAging skeletal muscle shows a drastic increase in the small heat shock proteins αB-crystallin/HspB5 and cvHsp/HspB7Eur J Cell Biol86629640200717761354

J GannonL StauntonK O’ConnellP DoranK OhlendieckPhosphoproteomic analysis of aged skeletal muscleInt J Mol Med2233422008

K O’ConnellP DoranJ GannonK OhlendieckLectin-based proteomic profiling of aged skeletal muscle: decreased pyruvate kinase isozyme M1 exhibits drastically increased levels of N-glycosylationEur J Cell Biol877938052008

P DoranK O’ConnellJ GannonM KavanaghK OhlendieckOpposite pathobiochemical fate of pyruvate kinase and adenylate kinase in aged rat skeletal muscle as revealed by proteomic DIGE analysisProteomics8364377200810.1002/pmic.20070047518050275

D CapitanioM VassoC FaniaM MoriggiA ViganoP ProcacciV MagnaghiC GelfiComparative proteomic profile of rat sciatic nerve and gastrocnemius muscle tissues in ageing by 2-D DIGEProteomics920042020200910.1002/pmic.20070116219333999

J GannonP DoranA KirwanK OhlendieckDrastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old ageEur J Cell Biol88685700200910.1016/j.ejcb.2009.06.00419616867

A LombardiE SilvestriF CioffiR SeneseA LanniF GogliaP de LangeM MorenoDefining the transcriptomic and proteomic profiles of rat ageing skeletal muscle by the use of a cDNA array, 2D- and Blue native-PAGE approachJ Proteomics72708721200910.1016/j.jprot.2009.02.00719268720

K O’ConnellK OhlendieckProteomic DIGE analysis of the mitochondria-enriched fraction from aged rat skeletal muscleProteomics955095524200919834913

P DonoghueL StauntonE MullenG ManningK OhlendieckDIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult vs. aged gastrocnemius tissueJ Proteomics714411453201010.1016/j.jprot.2010.01.01420153846

C GelfiA ViganoM RipamontiA PontoglioS BegumMA PellegrinoB GrassiR BottinelliR WaitP CerretelliThe human muscle proteome in agingJ Proteome Res513441353200610.1021/pr050414x16739986

L StauntonK O’ConnellK OhlendieckProteomic profiling of mitochondrial enzymes during skeletal muscle agingJ Aging Res2011908035201110.4061/2011/90803521437005

K OhlendieckProteomic profiling of fast-to-slow muscle transitions during agingFront Physiol2105201122207852

P FremontPM CharestC CotePA RogersCarbonic anhydrase III in skeletal muscle fibers: an immunocytochemical and biochemical studyJ Histochem Cytochem36775782198810.1177/36.7.31334073133407

R SchäferU KnaufM ZweyerO HögemeierF de GuarriniX LiuHJ EichhornFW KochRR MundegarI ErzenA WernigAge dependence of the human skeletal muscle stem cell in forming muscle tissueArtif Organs30130140200616480387

L StauntonH JockuschC WiegandT AlbrechtK OhlendieckIdentification of secondary effects of hyperexcitability by proteomic profiling of myotonic mouse muscleMol Biosyst724802489201110.1039/c1mb05043e21629954

MM BradfordA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnal Biochem72248254197610.1016/0003-2697(76)90527-3942051

T RabilloudM ChevalletS LucheC LelongTwo-dimensional gel electrophoresis in proteomics: Past, present and futureJ Proteomics7320642077201010.1016/j.jprot.2010.05.01620685252

L StauntonH JockuschK OhlendieckProteomic analysis of muscle affected by motor neuron degeneration: the wobbler mouse model of amyotrophic lateral sclerosisBiochem Biophys Res Commun406595600201110.1016/j.bbrc.2011.02.09921354103

C LewisK OhlendieckMass spectrometric identification of dystrophin isoform Dp427 by on-membrane digestion of sarcolemma from skeletal muscleAnal Biochem404197203201010.1016/j.ab.2010.05.01720507823

A ShevchenkoH TomasJ HavlisJV OlsenM MannIn-gel digestion for mass spectrometric characterization of proteins and proteomesNat Protoc128562860200610.1038/nprot.2006.46817406544

T LangT StreeperP CawthonK BaldwinDR TaaffeTB HarrisSarcopenia: etiology, clinical consequences, intervention, and assessmentOsteoporos Int21543559201010.1007/s00198-009-1059-y19779761

LJ TanSL LiuSF LeiCJ PapasianHW DengMolecular genetic studies of gene identification for sarcopeniaHum Genet131131201210.1007/s00439-011-1040-721706341

SY KhaitlinaFunctional specificity of actin isoformsInt Rev Cytol2023598200110.1016/S0074-7696(01)02003-411061563

C GeersG GrosCarbon dioxide transport and carbonic anhydrase in blood and musclePhysiol Rev80681715200010747205

P WetzelG GrosInhibition and kinetic properties of membrane-bound carbonic anhydrases in rabbit skeletal musclesArch Biochem Biophys356151158199810.1006/abbi.1998.07629705205

P WetzelT KleinkeS PapadopoulosG GrosInhibition of muscle carbonic anhydrase slows the Ca²⁺ transient in rat skeletal muscle fibersAm J Physiol283C1242C1253200210.1152/ajpcell.00106.200212225987

P FremontH RiverinJ FrenettePA RogersC CoteFatigue and recovery of rat soleus muscle are influenced by inhibition of an intracellular carbonic anhydrase isoformAm J Physiol260R615R62119912001010

C BrownsonH IsenbergW BrownS SalmonsY EdwardsChanges in skeletal muscle gene transcription induced by chronic stimulationMuscle Nerve1111831189198810.1002/mus.8801111133147374

C BrownsonP LoughnaAlterations in the mRNA levels of two metabolic enzymes in rat skeletal muscle during stretch-induced hypertrophy and disuse atrophyPfluegers Arch431990992199610.1007/s0042400500978927521

CH CoteF AmbrosioG PerreaultMetabolic and contractile influence of carbonic anhydrase III in skeletal muscle is age dependentAm J Physiol276R559R56519999950937

AH WuMB PerrymanClinical applications of muscle enzymes and proteinsCurr Opin Rheumatol481582019921457275

HK VäänänenTE TakalaU TolonenJ VuoriVV MyllyläMuscle-specific carbonic anhydrase III is a more sensitive marker of muscle damage than creatine kinase in neuromuscular disordersArch Neurol451254125619883142447

P BrancaccioG LippiN MaffulliBiochemical markers of muscular damageClin Chem Lab Med48757767201010.1515/CCLM.2010.179

P DoranG MartinP DowlingH JockuschK OhlendieckProteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSPProteomics646104621200610.1002/pmic.20060008216835851

E MullenK OhlendieckProteomic profiling of non-obese type 2 diabetic skeletal muscleInt J Mol Med25445458201020127051

T WallimannM Tokarska-SchlattnerU SchlattnerThe creatine kinase system and pleiotropic effects of creatineAmino Acids4012711296201110.1007/s00726-011-0877-321448658

M YanezJ Gil-LongoM Campos-ToimilCalcium binding proteinsAdv Exp Med Biol740461482201210.1007/978-94-007-2888-2_19

W TangS SencerSL HamiltonCalmodulin modulation of proteins involved in excitation-contraction couplingFront Biosci7d1583d1589200210.2741/tang12045019

P TaviH WesterbladThe role of in vivo Ca²⁺ signals acting on Ca²⁺-calmodulin-dependent proteins for skeletal muscle plasticityJ Physiol589502150312011

K OhlendieckProteomics of skeletal muscle glycolysisBiochim Biophys Acta180420892101201010.1016/j.bbapap.2010.08.00120709194

TE JensenEA RichterRegulation of glucose and glycogen metabolism during and after exerciseJ Physiol59010691076201210.1113/jphysiol.2011.22497222199166

RN NishimuraFR SharpHeat shock proteins and neuromuscular diseaseMuscle Nerve32693709200510.1002/mus.2037315962334

V BonifatiBA OostraP HeutinkLinking DJ-1 to neuro-degeneration offers novel insights for understanding the pathogenesis of Parkinson’s diseaseJ Mol Med82163174200414712351