1
|
Writing Group Members; Mozaffarian D,
Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de
Ferranti S, Després JP, et al: Heart disease and stroke
statistics-2016 update: A report from the American heart
association. Circulation. 133:e338–e360. 2016. View Article : Google Scholar
|
2
|
Hua F, Tang H, Wang J, Prunty MC, Hua XD,
Sayeed L and Stein DG: TAK-242, an antagonist for Toll-like
receptor 4, protects against acute cerebral ischemia/reperfusion
injury in mice. J Cereb Blood Flow Metab. 35:536–542. 2015.
View Article : Google Scholar : PubMed/NCBI
|
3
|
El Amki M and Wegener S: Improving
cerebral blood flow after arterial recanalization: A novel
therapeutic strategy in stroke. Int J Mol Sci. 18:E26692017.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Zhang X, Chen L, Dang X, Liu J, Ito Y and
Sun W: Neuroprotective effects of total steroid saponins on
cerebral ischemia injuries in an animal model of focal
ischemia/reperfusion. Planta Med. 80:637–644. 2014. View Article : Google Scholar : PubMed/NCBI
|
5
|
Melani A, Dettori I, Corti F, Cellai L and
Pedata F: Time-course of protection by the selective A2A
receptor antagonist SCH58261 after transient focal cerebral
ischemia. Neurol Sci. 36:1441–1448. 2015. View Article : Google Scholar : PubMed/NCBI
|
6
|
Zhang R, Xu M, Wang Y, Xie F, Zhang G and
Qin XY: Nrf2-a promising therapeutic target for defensing against
oxidative stress in stroke. Mol Neurobiol. 54:6006–6017. 2017.
View Article : Google Scholar
|
7
|
Žitňanová I, Šiarnik P, Kollár B, Chomová
M, Pazderová P, Andrezálová L, JeDoviIová M, Koňariková K,
Laubertová L, Krivošíková Z, et al: Oxidative stress markers and
their dynamic changes in patients after acute ischemic stroke. Oxid
Med Cell Longev. 2016:97616972016. View Article : Google Scholar : PubMed/NCBI
|
8
|
Adibhatla RM and Hatcher JF: Altered lipid
metabolism in brain injury and disorders. Subcell Biochem.
49:241–268. 2008. View Article : Google Scholar : PubMed/NCBI
|
9
|
Guo J, Cheng C, Chen CS, Xing X, Xu G,
Feng J and Qin X: Overexpression of Fibulin-5 attenuates
ischemia/reperfu-sion injury after middle cerebral artery occlusion
in rats. Mol Neurobiol. 53:3154–3167. 2016. View Article : Google Scholar
|
10
|
Ashabi G, Khalaj L, Khodagholi F,
Goudarzvand M and Sarkaki A: Pre-treatment with metformin activates
Nrf2 antioxidant pathways and inhibits inflammatory responses
through induction of AMPK after transient global cerebral ischemia.
Metab Brain Dis. 30:747–754. 2015. View Article : Google Scholar
|
11
|
Ding Y, Chen M, Wang M, Li Y and Wen A:
Posttreatment with 11-keto-β-Boswellic acid ameliorates cerebral
ischemia reperfusion injury: Nrf2/HO-1 pathway as a potential
mechanism. Mol Neurobiol. 52:1430–1439. 2015. View Article : Google Scholar
|
12
|
Milanlioglu A, Aslan M, Ozkol H, Çilingir
V, Nuri Aydın M and Karadas S: Serum antioxidant enzymes activities
and oxidative stress levels in patientswith acute ischemic stroke:
Influence on neurological status and outcome. Wien Klin Wochenschr.
128:169–174. 2016. View Article : Google Scholar
|
13
|
Zhao J, Yu S, Zheng W, Feng G, Luo G, Wang
L and Zhao Y: Curcumin improves outcomes and attenuates focal
cerebral ischemic injury via antiapoptotic mechanisms in rats.
Neurochem Res. 35:374–379. 2010. View Article : Google Scholar
|
14
|
Chen S, Peng H, Rowat A, Gao F, Zhang Z,
Wang P, Zhang W, Wang X and Qu L: The effect of concentration and
duration of normobaric oxygen in reducing caspase-3 and -9
expression in a rat-model of focal cerebral ischaemia. Brain Res.
1618:205–211. 2015. View Article : Google Scholar : PubMed/NCBI
|
15
|
Wagner DC, Riegelsberger UM, Michalk S,
Härtig W, Kranz A and Boltze J: Cleaved caspase-3 expression after
experimental stroke exhibits different phenotypes and is
predominantly non-apoptotic. Brain Res. 1381:237–242. 2011.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Endres M, Namura S, Shimizu-Sasamata M,
Waeber C, Zhang L, Gómez-Isla T, Hyman BT and Moskowitz MA:
Attenuation of delayed neuronal death after mild focal ischemia in
mice by inhibition of the caspase family. J Cereb Blood Flow Metab.
18:238–247. 1998. View Article : Google Scholar : PubMed/NCBI
|
17
|
Ma J, Endres M and Moskowitz MA:
Synergistic effects of caspase inhibitors and MK-801 in brain
injury after transient focal cerebral ischaemia in mice. Br J
Pharmacol. 124:756–762. 1998. View Article : Google Scholar : PubMed/NCBI
|
18
|
Sugawara T, Lewén A, Gasche Y, Yu FS and
Chan P: Overexpression of SOD1 protects vulnerable motor neurons
after spinal cord injury by attenuating mitochondrial cytochrome c
release. FASEB J. 16:1997–1999. 2002. View Article : Google Scholar : PubMed/NCBI
|
19
|
Tsang SW and Bian ZX: Anti-fibrotic and
Anti-tumorigenic effects of rhein, a natural anthraquinone
derivative, in mammalian stellate and carcinoma cells. Phytother
Res. 29:407–414. 2015. View
Article : Google Scholar
|
20
|
Liu J, Uematsu H, Tsuchida N and Ikeda MA:
Essential role of caspase-8 in p53/p73-dependent apoptosis induced
by etoposide in head and neck carcinoma cells. Mol Cancer.
10:952011. View Article : Google Scholar : PubMed/NCBI
|
21
|
Cong XD, Ding MJ, Dai DZ, Wu Y, Zhang Y
and Dai Y: ER stress, p66shc, and p-Akt/Akt mediate
adjuvant-induced inflammation, which is blunted by argirein, a
supermolecule and rhein in rats. Inflammation. 35:1031–1040. 2012.
View Article : Google Scholar
|
22
|
Gao Y and Chen X: Rhein exerts pro-and
anti-inflammatory actions by targeting IKKβ inhibition in
LPS-activated macrophages. Free Radic Biol Med. 72:104–112. 2014.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Wang Y, Fan R, Luo J, Tang T, Xing Z, Xia
Z, Peng W, Wang W, Lv H, Huang W, et al: An ultra high performance
liquid chromatography with tandem mass spectrometry method for
plasma and cerebrospinal fluid pharmacokinetics of rhein in
patients with traumatic brain injury after administration of
rhubarb decoction. J Sep Sci. 38:1100–1108. 2015. View Article : Google Scholar : PubMed/NCBI
|
24
|
Lam BY, Lo AC, Sun X, Luo HW, Chung SK and
Sucher NJ: Neuroprotective effects of tanshinones in transient
focal cerebral ischemia in mice. Phytomedicine. 10:286–291. 2003.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Li H, Deng CQ, Chen BY, Zhang SP, Liang Y
and Luo XG: Total saponins of Panax Notoginseng modulate the
expression of caspases and attenuate apoptosis in rats following
focal cerebral ischemia-reperfusion. J Ethnopharmacol. 121:412–418.
2009. View Article : Google Scholar
|
26
|
Zhao Q, Cheng X, Wang X, Wang J, Zhu Y and
Ma X: Neuroprotective effect and mechanism of Mu-Xiang-You-Fang on
cerebral ischemia-reperfusion injury in rats. J Ethnopharmacol.
192:140–147. 2016. View Article : Google Scholar : PubMed/NCBI
|
27
|
Lian Y, Xie L, Chen M and Chen L: Effects
of an astragalus polysaccharide and rhein combination on apoptosis
in rats with chronic renal failure. Evid Based Complement Alternat
Med. 2014:2718622014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Genovese T, Mazzon E, Paterniti I,
Esposito E, Bramanti P and Cuzzocrea S: Modulation of NADPH oxidase
activation in cerebral ischemia/reperfusion injury in rats. Brain
Res. 1372:92–102. 2011. View Article : Google Scholar
|
29
|
Longa EZ, Weinstein PR, Carlson S and
Cummins R: Reversible middle cerebral artery occlusion without
craniectomy in rats. Stroke. 20:84–91. 1989. View Article : Google Scholar : PubMed/NCBI
|
30
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
31
|
Kaushal V and Schlichter LC: Mechanisms of
microglia-mediated neurotoxicity in a new model of the stroke
penumbra. J Neurosci. 28:2221–2230. 2008. View Article : Google Scholar : PubMed/NCBI
|
32
|
Browning JD and Horton JD: Molecular
mediators of hepatic steatosis and liver injury. J Clin Invest.
114:147–152. 2004. View Article : Google Scholar : PubMed/NCBI
|
33
|
Rosen DR, Siddique T, Patterson D,
Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP,
Deng HX, et al: Mutations in Cu/Zn superoxide dismutase gene are
associated with familial amyotrophic lateral sclerosis. Nature.
362:59–62. 1993. View Article : Google Scholar : PubMed/NCBI
|
34
|
Vakili A, Sharifat S, Akhavan MM and
Bandegi AR: Effect of lavender oil (Lavandula angustifolia) on
cerebral edema and its possible mechanisms in an experimental model
of stroke. Brain Res. 1548:56–62. 2014. View Article : Google Scholar : PubMed/NCBI
|
35
|
Rodrigo R, Fernández-Gajardo R, Gutiérrez
R, Matamala JM, Carrasco R, Miranda-Merchak A and Feuerhake W:
Oxidative stress and pathophysiology of ischemic stroke: Novel
therapeutic opportunities. CNS Neurol Disord Drug Targets.
12:698–714. 2013. View Article : Google Scholar : PubMed/NCBI
|
36
|
Schettler V, Methe H, Staschinsky D,
Schuff-Werner P, Müller GA and Wieland E: Review: The
oxidant/antioxidant balance during regular low density lipoprotein
apheresis. Ther Apher. 3:219–226. 1999. View Article : Google Scholar : PubMed/NCBI
|
37
|
Fulda S, Galluzzi L and Kroemer G:
Targeting mitochondria for cancer therapy. Nat Rev Drug Discov.
9:447–464. 2010. View Article : Google Scholar : PubMed/NCBI
|
38
|
Circu ML and Aw TY: Reactive oxygen
species, cellular redox systems, and apoptosis. Free Radic Biol
Med. 48:749–762. 2010. View Article : Google Scholar : PubMed/NCBI
|
39
|
Carmona-Gutierrez D, Eisenberg T, Büttner
S, Meisinger C, Kroemer G and Madeo F: Apoptosis in yeast:
Triggers, pathways, subroutines. Cell Death Differ. 17:763–773.
2010. View Article : Google Scholar : PubMed/NCBI
|
40
|
Fuchs Y and Steller H: Programmed cell
death in animal development and disease. Cell. 147:742–758. 2011.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Zhen YF, Wang GD, Zhu LQ, Tan SP, Zhang
FY, Zhou XZ and Wang XD: P53 dependent mitochondrial permeability
transition pore opening is required for dexamethasone-induced death
of osteoblasts. J Cell Physiol. 229:1475–1483. 2014. View Article : Google Scholar : PubMed/NCBI
|
42
|
Matés JM, Segura JA, Alonso FJ and Márquez
J: Intracellular redox status and oxidative stress: Implications
for cell proliferation, apoptosis, and carcinogenesis. Arch
Toxicol. 82:273–299. 2008. View Article : Google Scholar : PubMed/NCBI
|
43
|
Sugawara T, Noshita N, Lewén A, Gasche Y,
Ferrand-Drake M, Fujimura M, Morita-Fujimura Y and Chan PH:
Overexpression of copper/zinc superoxide dismutase in transgenic
rats protects vulnerable neurons against ischemic damage by
blocking the mitochondrial pathway of caspase activation. J
Neurosci. 22:209–217. 2002.PubMed/NCBI
|
44
|
Fahmi T, Branch D, Nima ZA, Jang DS,
Savenka AV, Biris AS and Basnakian AG: Mechanism of
graphene-induced cytotoxicity: Role of endonucleases. J Appl
Toxicol. 37:1325–1332. 2017. View Article : Google Scholar : PubMed/NCBI
|
45
|
Zhou X, Patel D, Sen S, Shanmugam V,
Sidawy A, Mishra L and Nguyen BN: Poly-ADP-ribose polymerase
inhibition enhances ischemic and diabetic wound healing by
promoting angiogenesis. J Vasc Surg. 65:1161–1169. 2017. View Article : Google Scholar
|
46
|
Broughton BR, Reutens DC and Sobey CG:
Apoptotic mechanisms after cerebral ischemia. Stroke. 40:e331–e339.
2009. View Article : Google Scholar : PubMed/NCBI
|
47
|
Rami A, Bechmann I and Stehle JH:
Exploiting endogenous anti-apoptotic proteins for novel therapeutic
strategies in cerebral ischemia. Prog Neurobiol. 85:273–296. 2008.
View Article : Google Scholar : PubMed/NCBI
|
48
|
Budihardjo I, Oliver H, Lutter M, Luo X
and Wang X: Biochemical pathways of caspase activation during
apoptosis. Annu Rev Cell Dev Biol. 15:269–290. 1999. View Article : Google Scholar : PubMed/NCBI
|
49
|
Wang X: The expanding role of mitochondria
in apoptosis. Genes Dev. 15:2922–2933. 2001.PubMed/NCBI
|
50
|
Rossé T, Olivier R, Monney L, Rager M,
Conus S, Fellay I, Jansen B and Borner C: Bcl-2 prolongs cell
survival after BAX-induced release of cytochrome c. Nature.
391:496–499. 1998. View
Article : Google Scholar : PubMed/NCBI
|
51
|
Van Delft MF and Huang DC: How the Bcl-2
family of proteins interact to regulate apoptosis. Cell Res.
16:203–213. 2006. View Article : Google Scholar : PubMed/NCBI
|
52
|
Wang GH, Lan R, Zhen XD, Zhang W, Xiang J
and Cai DF: An-Gong-Niu-Huang Wan protects against cerebral
ischemia induced apoptosis in rats: Up-regulation of Bcl-2 and
down-regulation of BAX and caspase-3. J Ethnopharmacol.
154:156–162. 2014. View Article : Google Scholar : PubMed/NCBI
|
53
|
Zhao P, Zhou R, Zhu XY, Hao YJ, Li N, Wang
J, Niu Y, Sun T, Li YX and Yu JQ: Matrine attenuates focal cerebral
ischemic injury by improving antioxidant activity and inhibiting
apoptosis in mice. Int J Mol Med. 36:633–644. 2015. View Article : Google Scholar : PubMed/NCBI
|
54
|
Lee SR, Lok J, Rosell A, Kim HY, Murata Y,
Atochin D, Huang PL, Wang X, Ayata C, Moskowitz MA and Lo EH:
Reduction of hippocampal cell death and proteolytic responses in
tissue plasminogen activator knockout mice after transient global
cerebral ischemia. Neuroscience. 150:50–57. 2007. View Article : Google Scholar : PubMed/NCBI
|
55
|
Pérez-Garijo A: When dying is not the end:
Apoptotic caspases as drivers of proliferation. Semin Cell Dev
Biol. S1084–9521(17): 30500–1. 2017.
|
56
|
Liu J, Chen Z, Zhang Y, Zhang M, Zhu X,
Fan Y, Shi S, Zen K and Liu Z: Rhein protects pancreatic β-cells
from dynamin-related protein-1-mediated mitochondrial fission and
cell apoptosis under hyperglycemia. Diabetes. 62:3927–3935. 2013.
View Article : Google Scholar : PubMed/NCBI
|
57
|
Liu H, Zhou Y and Tang L: Caffeine induces
sustained apoptosis of human gastric cancer cells by activating the
caspase9/caspase3 signalling pathway. Mol Med Rep. 16:2445–2454.
2017. View Article : Google Scholar : PubMed/NCBI
|
58
|
Topçu Y, Bayram E, Ozbal S, Yiş U, Tuğyan
K, Karaoğlu P, Kumral A, Yılmaz O and Kurul SH: Zonisamide
attenuates hyperoxia-induced apoptosis in the developing rat brain.
Neurol Sci. 35:1769–1775. 2014. View Article : Google Scholar : PubMed/NCBI
|
59
|
Rami A, Sims J, Botez G and Winckler J:
Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3
activation and DNA-fragmentation in the human hippocampus after
cerebral ischemia. Neurochem Int. 43:79–87. 2003. View Article : Google Scholar : PubMed/NCBI
|
60
|
Le DA, Wu Y, Huang Z, Matsushita K,
Plesnila N, Augustinack JC, Hyman BT, Yuan J, Kuida K, Flavell RA
and Moskowitz MA: Caspase activation and neuroprotection in
caspase-3 deficient mice after in vivo cerebral ischemia and in
vitro oxygen glucose deprivation. Proc Natl Acad Sci USA.
99:15188–15193. 2002. View Article : Google Scholar
|
61
|
Wang N, Zhang Y, Wu L, Wang Y, Cao Y, He
L, Li X and Zhao J: Puerarin protected the brain from cerebral
ischemia injury via astrocyte apoptosis inhibition.
Neuropharmacology. 79:282–289. 2014. View Article : Google Scholar
|