1
|
Global Burden of Disease Cancer
Collaboration; Fitzmaurice C, Dicker D, Pain A, Hamavid H,
Moradi-Lakeh M, MacIntyre MF, Allen C, Hansen G, Woodbrook R, et
al: The global burden of cancer 2013. JAMA Oncol. 1:505–527. 2015.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Jemal A, Siegel R, Ward E, Hao Y, Xu J,
Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin.
58:71–96. 2008. View Article : Google Scholar : PubMed/NCBI
|
3
|
Khushalani N: Cancer of the esophagus and
stomach. Mayo Clin Proc. 83:712–722. 2008. View Article : Google Scholar : PubMed/NCBI
|
4
|
Zhang XY and Zhang PY: Gastric cancer:
Somatic genetics as a guide to therapy. J Med Genet. 54:305–312.
2017. View Article : Google Scholar
|
5
|
Toiyama Y, Tanaka K, Kitajima T, Shimura
T, Imaoka H, Mori K, Okigami M, Yasuda H, Okugawa Y, Saigusa S, et
al: Serum angiopoietin-like protein 2 as a potential biomarker for
diagnosis, early recurrence and prognosis in gastric cancer
patients. Carcinogenesis. 36:1474–1483. 2015.PubMed/NCBI
|
6
|
Guo Y, Shi J, Zhang J, Li H, Liu B and Guo
H: Polypeptide N-acetylgalactosaminyltransferase-6 expression in
gastric cancer. Onco Targets Ther. 10:3337–3344. 2017. View Article : Google Scholar :
|
7
|
Lee JC, Lee SY, Kim CY and Yang DH:
Clinical utility of tumor marker cutoff ratio and a combination
scoring system of preoperative carcinoembryonic antigen,
carbohydrate antigen 19-9, carbohydrate antigen 72-4 levels in
gastric cancer. J Korean Surg Soc. 85:283–289. 2013. View Article : Google Scholar : PubMed/NCBI
|
8
|
Tocchi A, Costa G, Lepre L, Liotta G,
Mazzoni G, Cianetti A and Vannini P: The role of serum and gastric
juice levels of carcinoembryonic antigen, CA19.9 and CA72.4 in
patients with gastric cancer. J Cancer Res Clin Oncol. 124:450–455.
1998. View Article : Google Scholar : PubMed/NCBI
|
9
|
Zheng TH, Zhao JL and Guleng B: Advances
in molecular biomarkers for gastric cancer. Crit Rev Eukaryot Gene
Exp. 25:299–305. 2015. View Article : Google Scholar
|
10
|
Weaver BA: How Taxol/paclitaxel kills
cancer cells. Mol Biol Cell. 25:2677–2681. 2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Suzuki S, Sakurai K, Adachi K, Nagashima
S, Hara Y, Amano S, Enomoto K and Makishima M: Examination of the
response rate of paclitaxel and bevacizumab therapy for metastatic
advanced breast cancer according to the lymphopenia grade. Gan To
Kagaku Ryoho. 42:1249–1251. 2015.In Japanese. PubMed/NCBI
|
12
|
Li H, Dai M and Jia W: Paeonol attenuates
high-fat-diet-induced atherosclerosis in rabbits by
anti-inflammatory activity. Planta Med. 75:7–11. 2009. View Article : Google Scholar
|
13
|
Chunhu Z, Suiyu H, Meiqun C, Guilin X and
Yunhui L: Antiproliferative and apoptotic effects of paeonol on
human hepatocellular carcinoma cells. Anticancer Drugs. 19:401–409.
2008. View Article : Google Scholar : PubMed/NCBI
|
14
|
Zhang LH, Xiao PG and Huang Y: Recent
progresses in pharmacological and clinical studies of paeonol.
Zhongguo Zhong XI Yi Jie He Za Zhi. 16:187–190. 1996.In Chinese.
PubMed/NCBI
|
15
|
Sun GP, Wan X, Xu SP, Wang H, Liu SH and
Wang ZG: Antiproliferation and apoptosis induction of paeonol in
human esophageal cancer cell lines. Dis Esophagus. 21:723–729.
2008. View Article : Google Scholar : PubMed/NCBI
|
16
|
Sun GP, Wang H, Xu SP, Shen YX, Wu Q, Chen
ZD and Wei W: Anti-tumor effects of paeonol in a HepA-hepatoma
bearing mouse model via induction of tumor cell apoptosis and
stimulation of IL-2 and TNF-alpha production. Eur J Pharmacol.
584:246–252. 2008. View Article : Google Scholar : PubMed/NCBI
|
17
|
Wan XA, Sun GP, Wang H, Xu SP, Wang ZG and
Liu SH: Synergistic effect of paeonol and cisplatin on oesophageal
cancer cell lines. Dig Liver Dis. 40:531–539. 2008. View Article : Google Scholar : PubMed/NCBI
|
18
|
Xu SP, Sun GP, Shen YX, Peng WR, Wang H
and Wei W: Synergistic effect of combining paeonol and cisplatin on
apoptotic induction of human hepatoma cell lines. Acta Pharmacol
Sin. 28:869–878. 2007. View Article : Google Scholar : PubMed/NCBI
|
19
|
Wang F, Sun JY, Zhu YH, Liu NT, Wu YF and
Yu F: MicroRNA-181 inhibits glioma cell proliferation by targeting
cyclin B1. Mol Med Rep. 10:2160–2164. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Li N, Fan LL, Sun GP, Wan XA, Wang ZG, Wu
Q and Wang H: Paeonol inhibits tumor growth in gastric cancer in
vitro and in vivo. World J Gastroenterol. 16:4483–4490. 2010.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Sarada SK, Himadri P, Ruma D, Sharma SK,
Pauline T and Mrinalini: Selenium protects the hypoxia induced
apoptosis in neuroblastoma cells through upregulation of Bcl-2.
Brain Res. 1209:29–39. 2008. View Article : Google Scholar : PubMed/NCBI
|
22
|
Laenen G, Thorrez L, Bornigen D and Moreau
Y: Finding the targets of a drug by integration of gene expression
data with a protein interaction network. Mol Biosyst. 9:1676–1685.
2013. View Article : Google Scholar : PubMed/NCBI
|
23
|
Ma W, Yang D, Gu Y, Guo X, Zhao W and Guo
Z: Finding disease-specific coordinated functions by multi-function
genes: Insight into the coordination mechanisms in diseases.
Genomics. 94:94–100. 2009. View Article : Google Scholar : PubMed/NCBI
|
24
|
Ewald JA and Jarrard DF: Decreased Skp2
expression is necessary but not sufficient for therapy-induced
senescence in prostate cancer. Transl Oncol. 5:278–287. 2012.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
26
|
Vadlamudi R, Mandal M, Adam L, Steinbach
G, Mendelsohn J and Kumar R: Regulation of cyclooxygenase-2 pathway
by HER2 receptor. Oncogene. 18:305–314. 1999. View Article : Google Scholar : PubMed/NCBI
|
27
|
Elder DJ, Halton DE, Crew TE and Paraskeva
C: Apoptosis induction and cyclooxygenase-2 regulation in human
colorectal adenoma and carcinoma cell lines by the
cyclooxygenase-2-selective non-steroidal anti-inflammatory drug
NS-398. Int J Cancer. 86:553–560. 2000. View Article : Google Scholar : PubMed/NCBI
|
28
|
Li M, Tan SY and Wang XF: Paeonol exerts
an anticancer effect on human colorectal cancer cells through
inhibition of PGE2 synthesis and COX-2 expression. Oncol
Rep. 32:2845–2853. 2014. View Article : Google Scholar : PubMed/NCBI
|
29
|
Chen N, Liu D, Soromou LW, Sun J, Zhong W,
Guo W, Huo M, Li H, Guan S, Chen Z and Feng H: Paeonol suppresses
lipopoly-saccharide-induced inflammatory cytokines in macrophage
cells and protects mice from lethal endotoxin shock. Fundam Clin
Pharmacol. 28:268–276. 2014. View Article : Google Scholar
|
30
|
Fu PK, Wu CL, Tsai TH and Hsieh CL:
Anti-inflammatory and anticoagulative effects of paeonol on
LPS-induced acute lung injury in rats. Evid Based Complement
Alternat Med. 2012:8375132012. View Article : Google Scholar : PubMed/NCBI
|
31
|
Li X, Zhou Y, Yu C, Yang H, Zhang C, Ye Y
and Xiao S: Paeonol suppresses lipid accumulation in macrophages
via upregulation of the ATP-binding cassette transporter A1 and
downregulation of the cluster of differentiation 36. Int J Oncol.
46:764–774. 2015. View Article : Google Scholar
|
32
|
Demaria S, Pikarsky E, Karin M, Coussens
LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo
E, et al: Cancer and inflammation: Promise for biological therapy.
J Immunother. 33:335–351. 2010. View Article : Google Scholar : PubMed/NCBI
|
33
|
Yang H, Bocchetta M, Kroczynska B,
Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa
JR, et al: TNF-alpha inhibits asbestos-induced cytotoxicity via a
NF-kappaB-dependent pathway, a possible mechanism for
asbestos-induced oncogenesis. Proc Natl Acad Sci USA.
103:10397–10402. 2006. View Article : Google Scholar : PubMed/NCBI
|
34
|
Kumar A and Yu FS: Toll-like receptors and
corneal innate immunity. Curr Mol Med. 6:327–337. 2006. View Article : Google Scholar : PubMed/NCBI
|
35
|
Fan Y, Mao R and Yang J: NF-kappaB and
STAT3 signaling pathways collaboratively link inflammation to
cancer. Protein Cell. 4:176–185. 2013. View Article : Google Scholar : PubMed/NCBI
|
36
|
Gray GK, McFarland BC, Nozell SE and
Benveniste EN: NF-κB and STAT3 in glioblastoma: Therapeutic targets
coming of age. Expert Rev Neurother. 14:1293–1306. 2014. View Article : Google Scholar : PubMed/NCBI
|
37
|
Wang SW and Sun YM: The IL-6/JAK/STAT3
pathway: Potential therapeutic strategies in treating colorectal
cancer (Review). Int J Oncol. 44:1032–1040. 2014. View Article : Google Scholar : PubMed/NCBI
|
38
|
Sethi G, Sung B and Aggarwal BB: Nuclear
factor-kappaB activation: From bench to bedside. Exp Biol Med
(Maywood). 233:21–31. 2008. View Article : Google Scholar
|
39
|
Shishodia S and Aggarwal BB: Nuclear
factor-kappaB activation: A question of life or death. J Biochem
Mol Biol. 35:28–40. 2002.
|
40
|
Galang CK, García-Ramírez J, Solski PA,
Westwick JK, Der CJ, Neznanov NN, Oshima RG and Hauser CA:
Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent
gene expression, and inhibiting ets activation blocks Neu-mediated
cellular transformation. J Biol Chem. 271:7992–7998. 1996.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Cao N, Li S, Wang Z, Ahmed KM, Degnan ME,
Fan M, Dynlacht JR and Li JJ: NF-kappaB-mediated HER2
overexpression in radiation-adaptive resistance. Radiat Res.
171:9–21. 2009. View Article : Google Scholar : PubMed/NCBI
|
42
|
Guo G, Wang T, Gao Q, Tamae D, Wong P,
Chen T, Chen WC, Shively JE, Wong JY and Li JJ: Expression of ErbB2
enhances radiation-induced NF-kappaB activation. Oncogene.
23:535–545. 2004. View Article : Google Scholar : PubMed/NCBI
|
43
|
Pianetti S, Arsura M, Romieu-Mourez R,
Coffey RJ and Sonenshein GE: Her-2/neu overexpression induces
NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated
degradation of IkappaB-alpha that can be inhibited by the tumor
suppressor. PTEN Oncogene. 20:1287–1299. 2001. View Article : Google Scholar
|
44
|
Zhou BP, Hu MC, Miller SA, Yu Z, Xia W,
Lin SY and Hung MC: HER-2/neu blocks tumor necrosis factor-induced
apoptosis via the Akt/NF-kappaB pathway. J Biol Chem.
275:8027–8031. 2000. View Article : Google Scholar : PubMed/NCBI
|
45
|
Diehl N and Schaal H: Make yourself at
home: Viral hijacking of the PI3K/Akt signaling pathway. Viruses.
5:3192–3212. 2013. View Article : Google Scholar : PubMed/NCBI
|
46
|
Tian J, Zhang X, Wu H, Liu C, Li Z, Hu X,
Su S, Wang LF and Qu L: Blocking the PI3K/AKT pathway enhances
mammalian reovirus replication by repressing IFN-stimulated genes.
Front Microbiol. 6:8862015. View Article : Google Scholar : PubMed/NCBI
|