1
|
Park CH, Valore EV, Waring AJ and Ganz T:
Hepcidin, a urinary antimicrobial peptide synthesized in the liver.
J Biol Chem. 276:7806–7810. 2001. View Article : Google Scholar
|
2
|
Nemeth E, Tuttle MS, Powelson J, Vaughn
MB, Donovan A, Ward DM, Gnz T and Kaplan J: Hepcidin regulates
cellular iron efflux by binding to ferroportin and inducing its
internalization. Science. 306:2090–2093. 2004. View Article : Google Scholar : PubMed/NCBI
|
3
|
Nicolas G, Chauvet C, Viatte L, Danan JL,
Bigard X, Devaux I, Beaumont C, Kahn A and Vaulont S: The gene
encoding the iron regulatory peptide hepcidin is regulated by
anemia, hypoxia, and inflammation. J Clin Invest. 100:1037–1044.
2002. View Article : Google Scholar
|
4
|
Ganz T: Hepcidin and iron regulation, 10
years later. Blood. 117:4425–4433. 2011. View Article : Google Scholar : PubMed/NCBI
|
5
|
Drakesmith H and Prentice AM: Hepcidin and
the iron-infection axis. Science. 338:768–772. 2012. View Article : Google Scholar : PubMed/NCBI
|
6
|
Fleming RE and Ponka P: Iron overload in
human disease. N Engl J Med. 366:348–59. 2012. View Article : Google Scholar : PubMed/NCBI
|
7
|
Ganz T, Olbina G, Girelli D, Nemeth E and
Westerman M: Immunoassay for human serum hepcidin. Blood.
112:4292–4297. 2008. View Article : Google Scholar : PubMed/NCBI
|
8
|
Maes K, Nemeth E, Roodman GD, Huston A,
Esteve F, Freytes C, Callander N, Katodritou E, Tussing-Humphreys
L, Rivera S, et al: In anemia of multiple myeloma, hepcidin is
induced by increased bone morphogenetic protein 2. Blood.
116:3635–3644. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Pinnix ZK, Miller LD, Wang W, D’Agostino
R, Kute T, Willingham MC, Hatcher H, Tesfay L, Sui G, Di X, et al:
Ferroportin and iron regulation in breast cancer progression and
prognosis. Sci Transl Med. 2:43–56. 2010. View Article : Google Scholar
|
10
|
Babiak J and Rudel LL: Lipoproteins and
atherosclerosis. Baillieres Clin Endocrinol Metab. 1:515–550. 1987.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Ramos E, Rodriguez L, Rodriguez R, Hansen
M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E and Ganz T: Evidence
for distinct pathways of hepcidin regulation by acute and chronic
iron loading in mice. Hepatology. 53:1333–1341. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
Wang Y, Zhang X, Xu C, Zhang G, Zhang Z,
Yu P, Shan L, Sun Y and Wang Y: Synthesis and biological evaluation
of danshensu and tetramethylpyrazine conjugates as cardioprotective
agents. Chem Pharm Bull. 65:381–388. 2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Jiang YR and Chen KJ: Pharmacological
roles of ligustrazine in cardio-/cerebrovascular systems and its
progress in researches of clinical application. Zhongguo Zhong Xi
Yi Jie He Za Zhi. 33:707–711. 2013.In Chinese. PubMed/NCBI
|
14
|
Ganz T: Systemic iron homeostasis. Physiol
Rev. 93:1721–1741. 2013. View Article : Google Scholar : PubMed/NCBI
|
15
|
Ganz T and Nemeth E: Hepcidin and iron
homeostasis. Biochimica et Biophysica Acta (BBA) Mol Cell Res.
1823:1434–1443. 2012. View Article : Google Scholar
|
16
|
Miyazono K, Maeda S and Imamura T: BMP
receptor signaling: Transcriptional targets, regulation of signals,
and signaling cross-talk. Cytokine Growth Factor Rev. 16:251–263.
2005. View Article : Google Scholar : PubMed/NCBI
|
17
|
Babitt JL, Huang FW, Wrighting DM, Xia Y,
Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, et
al: Bone morphogenetic protein signaling by hemojuvelin regulates
hepcidin expression. Nat Genet. 38:531–539. 2006. View Article : Google Scholar : PubMed/NCBI
|
18
|
Verga Falzacappa MV, Vujic Spasic M,
Kessler R, Stolte J, Hentze MW and Muckenthaler MU: STAT3 mediates
hepatic hepcidin expression and its inflammatory stimulation.
Blood. 109:353–358. 2007. View Article : Google Scholar
|
19
|
Yu PB, Hong CC, Sachidanandan C, Babitt
JL, Deng DY, Hoyng SA, Lin HY, Bloch KD and Peterson RT:
Dorsomorphin inhibits BMP signals required for embryogenesis and
iron metabolism. Nat Chem Biol. 4:33–41. 2008. View Article : Google Scholar
|
20
|
Chen Y, Wang Z, Xu M, Wang X, Liu R, Liu
Q, Zhang Z, Xia T, Zhao J, Jiang G, et al: Nanosilver incurs an
adaptive shunt of energy metabolism mode to glycolysis in tumor and
nontumor cells. ACS Nano. 8:5813–5825. 2014. View Article : Google Scholar : PubMed/NCBI
|
21
|
Zhang S, Chen Y, Guo W, Yuan L, Zhang D,
Xu Y, Nemeth E, Ganz T and Liu S: Disordered hepcidin-ferroportin
signaling promotes breast cancer growth. Cell Signal. 26:2539–50.
2014. View Article : Google Scholar : PubMed/NCBI
|
22
|
Liu S, Suragani RN, Han A, Zhao W, Andrews
NC and Chen JJ: Deficiency of heme-regulated eIF2α kinase decreases
hepcidin expression and splenic iron in HFE−/− mice. Haematologica.
93:753–756. 2008. View Article : Google Scholar : PubMed/NCBI
|
23
|
Liu S, Suragani RN, Wang F, Han A, Zhao W,
Andrews NC and Chen JJ: The function of heme-regulated eIF2alpha
kinase in murine iron homeostasis and macrophage maturation. J Clin
Invest. 117:3296–305. 2007. View
Article : Google Scholar : PubMed/NCBI
|
24
|
Brissot P, Bardou-Jacquet E, Jouanolle A-M
and Loréal O: Iron disorders of genetic origin: A changing world.
Trends Mol Med. 707–713. 2011. View Article : Google Scholar : PubMed/NCBI
|
25
|
Sun MY, Zhang M, Chen SL, Zhang SP, Guo
CY, Wang JS, Liu X, Miao Y and Yin HJ: The influence of
hyperlipidemia on endothelial function of FPN1 Tek-cre mice and the
intervention effect of tetramethylpyrazine. Cell Physiol Biochemi.
47:119–128. 2018. View Article : Google Scholar
|
26
|
Kennedy DO and Wightman EL: Herbal
extracts and phytochemicals: Plant secondary metabolites and the
enhancement of human brain function. Adv Nutr. 2:32–50. 2011.
View Article : Google Scholar :
|
27
|
Ziegler G, Ploch M, Miettinen-Baumann A
and Collet W: Efficacy and tolerability of valerian extract LI 156
compared with oxazepam in the treatment of non-organic insomnia-a
randomized, double-blind, comparative clinical study. Eur J Med
Res. 7:480–486. 2002.
|
28
|
Guan Y, An P, Zhang Z, Zhang F, Yu Y, Wu
Q, Shi Y, Guo X, Tao Y and Wang F: Screening identifies the Chinese
medicinal plant Caulis Spatholobi as an effective HAMP expression
inhibitor. J Nutr. 143:1061–1066. 2013. View Article : Google Scholar : PubMed/NCBI
|
29
|
Zhang M, Liu J, Guo W, Liu X, Liu S and
Yin H: Icariin regulates systemic iron metabolism by increasing
hepatic hepcidin expression through Stat3 and Smad1/5/8 signaling.
Int J Mol Med. 37:1379–1388. 2016. View Article : Google Scholar : PubMed/NCBI
|
30
|
Chen Z, Huo JR, Yang L and Zhu HY: Effect
of ligustrazine on mice model of hepatic veno-occlusive disease
induced by Gynura segetum. J Gastroenterol Hepatol. 26:1016–1021.
2011. View Article : Google Scholar : PubMed/NCBI
|
31
|
Ganz T and Nemeth E: Hepcidin and
disorders of iron metabolism. Annu Rev Med. 62:347–360. 2011.
View Article : Google Scholar
|
32
|
Sen B, Saigal B, Parikh N, Gallick G and
Johnson FM: Sustained Src inhibition results in signal transducer
and activator of transcription 3 (STAT3) activation and cancer cell
survival via altered Janus-activated kinase-STAT3 binding. Cancer
Res. 69:1958–1965. 2009. View Article : Google Scholar : PubMed/NCBI
|
33
|
Derynck R and Zhang YE: Smad-dependent and
Smad independent pathways in TGF-beta family signalling. Nature.
425:577–584. 2003. View Article : Google Scholar : PubMed/NCBI
|
34
|
Hentze MW, Muckenthaler MU, Galy B and
Camaschella C: Two to tango: Regulation of Mammalian iron
metabolism. Cell. 142:24–38. 2010. View Article : Google Scholar : PubMed/NCBI
|