1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2017. CA Cancer J Clin. 67:7–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
2
|
Bruix J, Gores GJ and Mazzaferro V:
Hepatocellular carcinoma: Clinical frontiers and perspectives. Gut.
63:844–855. 2014. View Article : Google Scholar : PubMed/NCBI
|
3
|
Pan JH, Zhou H, Zhao XX, Ding H, Li W, Qin
L and Pan YL: Role of exosomes and exosomal microRNAs in
hepatocellular carcinoma: Potential in diagnosis and antitumour
treatments (Review). Int J Mol Med. 41:1809–1816. 2018.PubMed/NCBI
|
4
|
Burgess JK, Boustany S, Moir LM, Weckmann
M, Lau JY, Grafton K, Baraket M, Hansbro PM, Hansbro NG, Foster PS,
et al: Reduction of tumstatin in asthmatic airways contributes to
angio-genesis, inflammation, and hyperresponsiveness. Am J Respir
Crit Care Med. 181:106–115. 2010. View Article : Google Scholar
|
5
|
Liu Y, Li J, Xu H, Zhang Y, Liu Y and Liu
X: Mitochondria-mediated tumstatin peptide-induced HepG2 cell
apoptosis. Int J Mol Med. 24:653–659. 2009. View Article : Google Scholar : PubMed/NCBI
|
6
|
Hwang-Bo J, Park JH and Chung IS:
Tumstatin induces apoptosis mediated by Fas signaling pathway in
oral squamous cell carcinoma SCC-VII cells. Oncol Lett.
10:1016–1022. 2015. View Article : Google Scholar : PubMed/NCBI
|
7
|
Zhang P, Zhou Q, Tian L, Zhou X, Zhou Y
and Chen J: Experimental study of a novel tumstatin on C6 brain
glioma in vitro. Oncol Lett. 14:2845–2851. 2017. View Article : Google Scholar : PubMed/NCBI
|
8
|
Yan Y, Xu W, Qian H, Zhu W, Mao F and
Zhang X: Tumstatin45-132-TNFalpha suppresses tumour growth through
anti-angiogenic effects and cytotoxicity. Biotechnol Appl Biochem.
56:119–127. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Saus J, Wieslander J, Langeveld JP,
Quinones S and Hudson BG: Identification of the Goodpasture antigen
as the alpha 3(IV) chain of collagen IV. J Biol Chem.
263:13374–13380. 1988.PubMed/NCBI
|
10
|
Eikesdal HP, Sugimoto H, Birrane G,
Maeshima Y, Cooke VG, Kieran M and Kalluri R: Identification of
amino acids essential for the antiangiogenic activity of tumstatin
and its use in combination antitumor activity. Proc Natl Acad Sci
USA. 105:15040–15045. 2008. View Article : Google Scholar : PubMed/NCBI
|
11
|
Zhang X, Qi DD, Zhang TT, Chen QX, Wang
GZ, Sui GY, Hao XW, Sun S, Song X and Chen YL: Antitumor activity
of adenoviral vector containing T42 and 4xT42 peptide gene through
inducing apoptosis of tumor cells and suppressing angiogenesis. Mol
Med Rep. 11:2083–2091. 2015. View Article : Google Scholar
|
12
|
Wang F, Dong X, Xiu P, Zhong J, Wei H, Xu
Z, Li T, Liu F, Sun X and Li J: T7 peptide inhibits angiogenesis
via downregu-lation of angiopoietin-2 and autophagy. Oncol Rep.
33:675–684. 2015. View Article : Google Scholar
|
13
|
Yang Z and Klionsky DJ: Eaten alive: A
history of macroautophagy. Nat Cell Biol. 12:814–822. 2010.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Liu W, Wang X, Liu Z, Wang Y, Yin B, Yu P,
Duan X, Liao Z, Chen Y, Liu C, et al: SGK1 inhibition induces
autophagy-dependent apoptosis via the mTOR-Foxo3a pathway. Br J
Cancer. 117:1139–1153. 2017. View Article : Google Scholar : PubMed/NCBI
|
15
|
Tang ZH, Cao WX, Su MX, Chen X and Lu JJ:
Osimertinib induces autophagy and apoptosis via reactive oxygen
species generation in non-small cell lung cancer cells. Toxicol
Appl Pharmacol. 321:18–26. 2017. View Article : Google Scholar : PubMed/NCBI
|
16
|
Sun K, Guo XL, Zhao QD, Jing YY, Kou XR,
Xie XQ, Zhou Y, Cai N, Gao L, Zhao X, et al: Paradoxical role of
autophagy in the dysplastic and tumor-forming stages of
hepatocarcinoma development in rats. Cell Death Dis. 4:e5012013.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Zhong J, Dong X, Xiu P, Wang F, Liu J, Wei
H, Xu Z, Liu F, Li T and Li J: Blocking autophagy enhances
meloxicam lethality to hepatocellular carcinoma by promotion of
endoplasmic reticulum stress. Cell Prolif. 48:691–704. 2015.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Cosin-Roger J, Simmen S, Melhem H, Atrott
K, Frey-Wagner I, Hausmann M, de Vallière C, Spalinger MR,
Spielmann P, Wenger RH, et al: Hypoxia ameliorates intestinal
inflammation through NLRP3/mTOR downregulation and autophagy
activation. Nat Commun. 8:982017. View Article : Google Scholar : PubMed/NCBI
|
19
|
Shi ZY, Deng JX, Fu S, Wang L, Wang Q, Liu
B, Li YQ and Deng JB: Protective effect of autophagy in neural
ischemia and hypoxia: Negative regulation of the Wnt/β-catenin
pathway. Int J Mol Med. 40:1699–1708. 2017.PubMed/NCBI
|
20
|
Chen YF, Liu H, Luo XJ, Zhao Z, Zou ZY, Li
J, Lin XJ and Liang Y: The roles of reactive oxygen species (ROS)
and autophagy in the survival and death of leukemia cells. Crit Rev
Oncol Hematol. 112:21–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
21
|
Li R, Luo X, Zhu Y, Zhao L, Li L, Peng Q,
Ma M and Gao Y: ATM signals to AMPK to promote autophagy and
positively regulate DNA damage in response to cadmium-induced ROS
in mouse spermatocytes. Environ Pollut. 231:1560–1568. 2017.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z
and Shen G: Curcumin induces apoptosis and protective autophagy in
castration-resistant prostate cancer cells through iron chelation.
Drug Design Devel Ther. 11:431–439. 2017. View Article : Google Scholar
|
23
|
Zhang N, Wu Y, Lyu X, Li B, Yan X, Xiong
H, Li X, Huang G, Zeng Y, Zhang Y, et al: HSF1 upregulates ATG4B
expression and enhances epirubicin-induced protective autophagy in
hepa-tocellular carcinoma cells. Cancer Lett. 409:81–90. 2017.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Dong X, Li R, Xiu P, Dong X, Xu Z, Zhai B,
Liu F, Jiang H, Sun X, Li J and Qiao H: Meloxicam executes its
antitumor effects against hepatocellular carcinoma in
COX-2-dependent and -independent pathways. PLoS One. 9:e928642014.
View Article : Google Scholar
|
25
|
Chang H, Li X, Cai Q, Li C, Tian L, Chen
J, Xing X, Gan Y, Ouyang W and Yang Z: The PI3K/Akt/mTOR pathway is
involved in CVB3-induced autophagy of HeLa cells. Int J Mol Med.
40:182–192. 2017. View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang SS, Chen YH, Chen N, Wang LJ, Chen
DX, Weng HL, Dooley S and Ding HG: Hydrogen sulfide promotes
autophagy of hepatocellular carcinoma cells through the
PI3K/Akt/mTOR signaling pathway. Cell Death Dis. 8:e26882017.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Yao H and Han X and Han X: The
cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling
pathway. Am J Cardiovasc Drugs. 14:433–442. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Zhao R, Chen M, Jiang Z, Zhao F, Xi B,
Zhang X, Fu H and Zhou K: Platycodin-D induced autophagy in
non-small cell lung cancer cells via PI3K/Akt/mTOR and MAPK
signaling pathways. J Cancer. 6:623–631. 2015. View Article : Google Scholar : PubMed/NCBI
|
29
|
Huang KH, Kuo KL, Ho IL, Chang HC, Chuang
YT, Lin WC, Lee PY, Chang SC, Chiang CK, Pu YS, et al:
Celecoxib-induced cytotoxic effect is potentiated by inhibition of
autophagy in human urothelial carcinoma cells. PLoS One.
8:e820342013. View Article : Google Scholar : PubMed/NCBI
|
30
|
Goto T, Ishikawa H, Matsumoto K, Nishimura
D, Kusaba M, Taura N, Shibata H, Miyaaki H, Ichikawa T, Hamasaki K,
et al: Tum-1, a tumstatin fragment, gene delivery into
hepatocellular carcinoma suppresses tumor growth through inhibiting
angio-genesis. Int J Oncol. 33:33–40. 2008.PubMed/NCBI
|
31
|
Li YJ, Sun LC, He Y, Liu XH, Liu M, Wang
QM and Jin XM: The anti-tumor properties of two tumstatin peptide
fragments in human gastric carcinoma. Acta Pharmacol Sin.
30:1307–1315. 2009. View Article : Google Scholar : PubMed/NCBI
|
32
|
Wang Y, Yin RF and Teng JS: Tumstatin
induces apoptosis and stimulates phosphorylation of p65NF-κB in
human osteoblastic osteosarcoma Saos-2 cells. Oncol Rep.
35:3403–3408. 2016. View Article : Google Scholar : PubMed/NCBI
|
33
|
Sun C, He D, Ma C, Gao Z, Chen Y and Wang
S: Bifunctional fusion proteins derived from tumstatin and 4-1BBL
for targeted cancer therapy. Mol Pharm. 16:867–876. 2019.
View Article : Google Scholar
|
34
|
Grafton KT, Moir LM, Black JL, Hansbro NG,
Hansbro PM, Burgess JK and Oliver BG: LF-15 & T7, synthetic
peptides derived from tumstatin, attenuate aspects of airway
remodelling in a murine model of chronic OVA-induced allergic
airway disease. PLoS One. 9:e856552014. View Article : Google Scholar :
|
35
|
He Y, Jiang Y, Li YJ, Liu XH, Zhang L, Liu
LJ, Shi H, Li HN, Ma YC and Jin XM: 19-peptide, a fragment of
tumstatin, inhibits the growth of poorly differentiated gastric
carcinoma cells in vitro and in vivo. J Gastroenterol Hepatol.
25:935–941. 2010. View Article : Google Scholar : PubMed/NCBI
|
36
|
Bommareddy A, Hahm ER, Xiao D, Powolny AA,
Fisher AL, Jiang Y and Singh SV: Atg5 regulates phenethyl
isothio-cyanate-induced autophagic and apoptotic cell death in
human prostate cancer cells. Cancer Res. 69:3704–3712. 2009.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Kim RH, Coates JM, Bowles TL, McNerney GP,
Sutcliffe J, Jung JU, Gandour-Edwards R, Chuang FY, Bold RJ and
Kung HJ: Arginine deiminase as a novel therapy for prostate cancer
induces autophagy and caspase-independent apoptosis. Cancer Res.
69:700–708. 2009. View Article : Google Scholar : PubMed/NCBI
|
38
|
Shintani T and Klionsky DJ: Autophagy in
health and disease: A double-edged sword. Science. 306:990–995.
2004. View Article : Google Scholar : PubMed/NCBI
|
39
|
Xue JF, Shi ZM, Zou J and Li XL:
Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of
articular chondrocytes and attenuates inflammatory response in rats
with osteoarthritis. Biomed Pharmacother. 89:1252–1261. 2017.
View Article : Google Scholar : PubMed/NCBI
|