Open Access

[Comment] COVID‑19 vaccine safety

  • Authors:
    • Ronald N. Kostoff
    • Michael B. Briggs
    • Alan L. Porter
    • Demetrios A. Spandidos
    • Aristidis Tsatsakis
  • View Affiliations

  • Published online on: September 18, 2020     https://doi.org/10.3892/ijmm.2020.4733
  • Pages: 1599-1602
  • Copyright: © Kostoff et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

In response to the SARS‑CoV‑2 outbreak, and the resulting COVID‑19 pandemic, a global competition to develop an anti‑COVID‑19 vaccine has ensued. The targeted time frame for initial vaccine deployment is late 2020. The present article examines whether short‑term, mid‑term, and long‑term vaccine safety can be achieved under such an accelerated schedule, given the myriad vaccine‑induced mechanisms that have demonstrated adverse effects based on previous clinical trials and laboratory research. It presents scientific evidence of potential pitfalls associated with eliminating critical phase II and III clinical trials, and concludes that there is no substitute currently available for long‑term human clinical trials to ensure long‑term human safety.
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November-2020
Volume 46 Issue 5

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Copy and paste a formatted citation
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Spandidos Publications style
Kostoff RN, Briggs MB, Porter AL, Spandidos DA and Tsatsakis A: [Comment] COVID‑19 vaccine safety. Int J Mol Med 46: 1599-1602, 2020.
APA
Kostoff, R.N., Briggs, M.B., Porter, A.L., Spandidos, D.A., & Tsatsakis, A. (2020). [Comment] COVID‑19 vaccine safety. International Journal of Molecular Medicine, 46, 1599-1602. https://doi.org/10.3892/ijmm.2020.4733
MLA
Kostoff, R. N., Briggs, M. B., Porter, A. L., Spandidos, D. A., Tsatsakis, A."[Comment] COVID‑19 vaccine safety". International Journal of Molecular Medicine 46.5 (2020): 1599-1602.
Chicago
Kostoff, R. N., Briggs, M. B., Porter, A. L., Spandidos, D. A., Tsatsakis, A."[Comment] COVID‑19 vaccine safety". International Journal of Molecular Medicine 46, no. 5 (2020): 1599-1602. https://doi.org/10.3892/ijmm.2020.4733