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Functional integrity of dispersed islet cells attached to a two-dimensional microsupport.

  • Authors:
    • E Olivares
    • W J Malaisse

  • View Affiliations

  • Published online on: September 1, 2000     https://doi.org/10.3892/ijmm.6.3.313
  • Pages: 313-317
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Dispersed rat pancreatic islet cells were cultured overnight in the presence of polystyrene two-dimensional microsupports. About 1.7-1.9x10(6) cells attached to the microsupports (832 cm2) were found to display both an insulin content and secretory response to D-glucose and/or theophylline comparable to those otherwise found in cultured free islet cells. It is proposed that advantage could be taken of this approach to study the function of islet cells attached in a standardized number to such two-dimensional microsupports.

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Sep 2000
Volume 6 Issue 3

Print ISSN: 1107-3756
Online ISSN:1791-244X

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  • Journal Metrics
  • Impact Factor: 5.7
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 12.3
  • CiteScore Rank: Q1: #28/347 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 1.022
  • SCImago Journal Rank (SJR): 1.167
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Spandidos Publications style
Olivares E and Malaisse W: Functional integrity of dispersed islet cells attached to a two-dimensional microsupport.. Int J Mol Med 6: 313-317, 2000.
APA
Olivares, E., & Malaisse, W. (2000). Functional integrity of dispersed islet cells attached to a two-dimensional microsupport.. International Journal of Molecular Medicine, 6, 313-317. https://doi.org/10.3892/ijmm.6.3.313
MLA
Olivares, E., Malaisse, W."Functional integrity of dispersed islet cells attached to a two-dimensional microsupport.". International Journal of Molecular Medicine 6.3 (2000): 313-317.
Chicago
Olivares, E., Malaisse, W."Functional integrity of dispersed islet cells attached to a two-dimensional microsupport.". International Journal of Molecular Medicine 6, no. 3 (2000): 313-317. https://doi.org/10.3892/ijmm.6.3.313