EPIDERMAL GROWTH-FACTOR RECEPTOR EXPRESSION IN MALIGNANT OVARY, BENIGN OVARIAN-TUMORS AND NORMAL OVARY - A COMPARISON
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- Published online on: February 1, 1993 https://doi.org/10.3892/ijo.2.2.321
- Pages: 321-324
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Abstract
Epidermal growth factor receptor (EGFR) was assayed and compared in malignant ovaries, benign ovarian tumours and normal ovaries. The EGFR was present in 39.7% of malignant ovaries, 13.3% of benign ovarian tumours and in 15.4% of normal ovaries. In the malignant group 36 samples had a low affinity component, 27 had a high affinity component and 16 had both high and low affinity components. The benign ovarian group had 1 high affinity and 3 low affinity components while the normal ovaries had 3 high affinity and 5 low affinity components. The sensitivity of the EGFR assay was 39.7% and the specificity 85.4%.
