ARE THERE ESTROGEN-RECEPTORS IN HUMAN LARYNGEAL CANCERS
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- Published online on: July 1, 1993 https://doi.org/10.3892/ijo.3.1.95
- Pages: 95-98
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Abstract
The presence of estrogen receptors in laryngeal carcinoma is controversial; with two independent methods (testing the binding of monoclonal antibodies against receptor protein by immunohistochemistry binding of labelled H-3-estradiol with the charcoal-dextran method), the levels of ER were found to be, if any, extremely low and without correlation to age, sex and previous radiation therapy of the patient. Administration of antiestrogens (if rationalized by the presence of ER) is therefore not indicated.