We tested the therapeutic effect of vitamin C infusion treatment in patients with autoimmune disease or allergy, and found the trial to be a big success. The above clinical studies served to prove the validity of our speculation that vitamin C with its strong affinity for endocrine cells may enhance the function of the endocrines, and that the endocrines thus activated will in turn exert a beneficial influence on either autoimmune disease or allergy - a disease entity that is known to be responsive to glucocorticoid treatment. Experimental studies that have been conducted in parallel with our clinical studies were in agreement with our interpretation about the mechanism of vitamin C action - a finding which appears to be promising for a trial in AIDS patients. We next investigated the prospect of vitamin C infusion therapy in AIDS patients in the light of the historical development of natural science including microbiology, epidemiology and population ecology. Accumulated data were in support of the notion that AIDS is more akin to autoimmune disease than to venereal disease. Usefulness and limitation of vitamin C infusion treatment in the general crisis of the 20th Century world are discussed in relation to the population problem.

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