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COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES

  • Authors:
    • A DIB
    • J ADELAIDE
    • F COURJAL
    • A COURSEAUX
    • J JACQUEMIER
    • P GAUDRAY
    • C THEILLET
    • MJ PEBUSQUE
    • D BIRNBAUM

  • View Affiliations

  • Published online on: December 1, 1994     https://doi.org/10.3892/ijo.5.6.1375
  • Pages: 1375-1378
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Abstract

The CCND2 and FGF6 genes are both located at band p13 of human chromosome 12. The two genes are coamplified in some cases (3.6%) of breast tumors. They are physically linked within a 500 kb genomic segment. Thus, both 11q13 and 12p13 chromosomal regions host related linked cyclin and FGF genes, and can be amplified in human tumors. This strengthens the hypothesis of genome duplication involving chromosomes 11 and 12.

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December 1994
Volume 5 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Impact Factor: 4.5
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  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
DIB A, ADELAIDE J, COURJAL F, COURSEAUX A, JACQUEMIER J, GAUDRAY P, THEILLET C, PEBUSQUE M and BIRNBAUM D: COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES. Int J Oncol 5: 1375-1378, 1994.
APA
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P. ... BIRNBAUM, D. (1994). COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES. International Journal of Oncology, 5, 1375-1378. https://doi.org/10.3892/ijo.5.6.1375
MLA
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P., THEILLET, C., PEBUSQUE, M., BIRNBAUM, D."COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES". International Journal of Oncology 5.6 (1994): 1375-1378.
Chicago
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P., THEILLET, C., PEBUSQUE, M., BIRNBAUM, D."COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES". International Journal of Oncology 5, no. 6 (1994): 1375-1378. https://doi.org/10.3892/ijo.5.6.1375