Mechanisms of preferential metastasis of breast cancer to bone - (Review)
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- Published online on: July 1, 1996 https://doi.org/10.3892/ijo.9.1.103
- Pages: 103-109
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Abstract
Breast cancer frequently and preferentially spreads to bone. Once breast cancer colonizes bone, it is essentially incurable. The cellular and molecular mechanisms by which breast cancer selectively metastasizes to bone remain largely unknown. Elucidation of these mechanisms should lead to the development of effective and specific therapeutic strategies for bone metastasis of breast cancer.