Association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma of breast cancer

  • Authors:
    • Shan‑Shan Sun
    • Bin Zhang
    • Hong‑Meng Zhao
    • Xu‑Chen Cao
  • View Affiliations

  • Published online on: May 19, 2014     https://doi.org/10.3892/mco.2014.297
  • Pages: 623-629
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The aim of the present study was to evaluate the association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma. A total of 231 patients were retrospectively reviewed from January, 2011 to December, 2012. Statistical analysis was performed using Fisher's exact test, χ2 test, Spearman's correlation and logistic regression, as appropriate. Of the 231 patients who underwent mammography, malignant calcifications were significantly more frequent in carcinomas that were human epidermal growth factor receptor 2 (HER2)‑positive (P=0.001) or had a >2 cm size tumor (P=0.006). The pleomorphic‑type was correlated with a p53‑positive status (P=0.039) or lymph node metastasis (P=0.048), whereas the indistinct amorphous‑type was associated with a HER2‑positive status (P=0.026). An evident mass was frequently observed in higher Ki‑67 expression‑level tumors (P=0.002). In conclusion, the aforementioned correlations are noteworthy as they potentially reflect tumor attributes and may serve as a guide for treatment.
View Figures
View References

Related Articles

Journal Cover

July-August 2014
Volume 2 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Sun SS, Zhang B, Zhao HM and Cao XC: Association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma of breast cancer. Mol Clin Oncol 2: 623-629, 2014
APA
Sun, S., Zhang, B., Zhao, H., & Cao, X. (2014). Association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma of breast cancer. Molecular and Clinical Oncology, 2, 623-629. https://doi.org/10.3892/mco.2014.297
MLA
Sun, S., Zhang, B., Zhao, H., Cao, X."Association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma of breast cancer". Molecular and Clinical Oncology 2.4 (2014): 623-629.
Chicago
Sun, S., Zhang, B., Zhao, H., Cao, X."Association between mammographic features and clinicopathological characteristics in invasive ductal carcinoma of breast cancer". Molecular and Clinical Oncology 2, no. 4 (2014): 623-629. https://doi.org/10.3892/mco.2014.297