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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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May-2015 Volume 3 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Case Report

Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report

  • Authors:
    • Zejun Lu
    • Xiangfei Zhao
    • Henghu Fang
    • Sudong Wu
    • Juyi Wen
    • Xinhong Zhang
    • Jingbo Kang

  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, Naval General Hospital of People's Liberation Army, Beijing 100048, P.R. China
  • Pages: 581-583
    |
    Published online on: February 9, 2015
       https://doi.org/10.3892/mco.2015.507
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Abstract

For patients with locoregionally advanced nasopharyngeal carcinoma (NPC), radiotherapy, chemotherapy and even targeted therapy are widely accepted treatments. These treatments, although they mostly achieve locoregional tumor control, they may also be associated with complex post‑treatment changes, such as edema, loss of tissue planes, fibrosis, mucositis and scarring, which may interfere with the detection of local recurrence and the response to therapy. However, timely detection is crucial for deciding whether treatment modification or discontinuation is required. This is the case report of a 51‑year‑old nasopharyngeal carcinoma patient with cervical nodal metastases (CNM). Following radiotherapy, chemotherapy and targeted therapy, multislice spiral enhanced computed tomography (CT), enhanced magnetic resonance imaging (MRI) and 18F‑fluorodeoxyglucose (FDG) positron emission tomography (PET)̸CT of the neck were performed to compare the extent of the CNM. The enhanced CT and MRI images were unremarkable, whereas the 18F‑FDG PET̸CT images revealed the exact recurrence or remission. Therefore, 18F‑FDG PET/CT exhibits a better sensitivity and specificity for evaluating the response to combined treatment compared to CT and/or MRI.
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Copy and paste a formatted citation
Spandidos Publications style
Lu Z, Zhao X, Fang H, Wu S, Wen J, Zhang X and Kang J: Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report. Mol Clin Oncol 3: 581-583, 2015.
APA
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., & Kang, J. (2015). Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report. Molecular and Clinical Oncology, 3, 581-583. https://doi.org/10.3892/mco.2015.507
MLA
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., Kang, J."Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report". Molecular and Clinical Oncology 3.3 (2015): 581-583.
Chicago
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., Kang, J."Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report". Molecular and Clinical Oncology 3, no. 3 (2015): 581-583. https://doi.org/10.3892/mco.2015.507
Copy and paste a formatted citation
x
Spandidos Publications style
Lu Z, Zhao X, Fang H, Wu S, Wen J, Zhang X and Kang J: Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report. Mol Clin Oncol 3: 581-583, 2015.
APA
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., & Kang, J. (2015). Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report. Molecular and Clinical Oncology, 3, 581-583. https://doi.org/10.3892/mco.2015.507
MLA
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., Kang, J."Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report". Molecular and Clinical Oncology 3.3 (2015): 581-583.
Chicago
Lu, Z., Zhao, X., Fang, H., Wu, S., Wen, J., Zhang, X., Kang, J."Clinical value of 18F‑fluorodeoxyglucose positron emission tomography/computed tomography in evaluating relapsed and refractory nasopharyngeal carcinoma: A case report". Molecular and Clinical Oncology 3, no. 3 (2015): 581-583. https://doi.org/10.3892/mco.2015.507
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