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Molecular and Clinical Oncology
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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Article

Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy

  • Authors:
    • Yasuo Hamamoto
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    Affiliations: Department of Medical Oncology, Tochigi Cancer Center, Utsunomiya, Tochigi 320-0834, Japan
  • Pages: 539-542
    |
    Published online on: February 16, 2015
       https://doi.org/10.3892/mco.2015.510
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Abstract

Peritoneal metastasis (PM) in gastric cancer (GC) is often the cause of several complications, including ascites and bowel obstruction. the prognosis of patients with extensive PM is poor. There are only limited data available on clinical characteristics regarding the period between the initiation of chemotherapy until the death of the patient. We conducted a retrospective study to determine the frequency of major events during and after palliative chemotherapy in advanced GC patients with PM. The records of patients who received first‑line palliative chemotherapy at the Tochigi Cancer Center for locally advanced or metastatic disease were reviewed. The extracted information included treatments received and emerging complications. Overall survival was compared between patients with and those without PM. A total of 97 patients were reviewed and the prevalence of complications with or without concurrent PM were as follows: bowel obstruction: PM, 37% (16/43) and non‑PM, 20% (11/54) (P=0.0664); ascites: PM, 49% (21/43) and non‑PM, 7% (4/54) (P<0.0001). The clinical characteristics of patients with PM from GC are unique. Therefore, it is crucial to consider PM as a predictive sign and an important factor when making clinical decisions and developing treatment strategies.
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Copy and paste a formatted citation
Spandidos Publications style
Hamamoto Y: Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy. Mol Clin Oncol 3: 539-542, 2015.
APA
Hamamoto, Y. (2015). Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy. Molecular and Clinical Oncology, 3, 539-542. https://doi.org/10.3892/mco.2015.510
MLA
Hamamoto, Y."Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy". Molecular and Clinical Oncology 3.3 (2015): 539-542.
Chicago
Hamamoto, Y."Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy". Molecular and Clinical Oncology 3, no. 3 (2015): 539-542. https://doi.org/10.3892/mco.2015.510
Copy and paste a formatted citation
x
Spandidos Publications style
Hamamoto Y: Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy. Mol Clin Oncol 3: 539-542, 2015.
APA
Hamamoto, Y. (2015). Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy. Molecular and Clinical Oncology, 3, 539-542. https://doi.org/10.3892/mco.2015.510
MLA
Hamamoto, Y."Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy". Molecular and Clinical Oncology 3.3 (2015): 539-542.
Chicago
Hamamoto, Y."Complications in advanced or recurrent gastric cancer patients with peritoneal metastasis during and after palliative systemic chemotherapy". Molecular and Clinical Oncology 3, no. 3 (2015): 539-542. https://doi.org/10.3892/mco.2015.510
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