Investigation of the potential role of preoperative chemotherapy in treatment for gastric cancer with outlet obstruction

  • Authors:
    • Xuelong Jiao
    • Yanbing Zhou
  • View Affiliations

  • Published online on: June 24, 2015     https://doi.org/10.3892/mco.2015.587
  • Pages: 1177-1183
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Abstract

Preoperative chemotherapy is currently recognized as the recommended treatment for advanced gastric cancer. Whether there is a role of preoperative chemotherapy in the treatment for advanced gastric cancer with gastric outlet obstruction (GOO) is unknown. In order to explore the potential feasibility of preoperative chemotherapy for advanced gastric cancer with GOO, and to encourage the probe into optimal treatment strategies for advanced gastric cancer with GOO in the current era of preoperative chemotherapy prevailing, a systematic literature search was conducted with a multistage process. The characteristics of the retrieved publications were summarized and the essential information was extracted. Only 11 studies associated with preoperative chemotherapy for advanced gastric cancer with GOO were identified. Among them, 9 were case reports, while the other 2 were research reports of retrospective studies. None were of prospective studies. The paucity of the literature in this field is a marked finding of the present study, which reports the emerging attempts at preoperative chemotherapy for advanced gastric cancer patients with GOO, as no high‑quality data are available. The definite role of chemotherapy as an initial treatment for advanced gastric cancer patients with GOO remains unclear. Clinical trials are expected to be conducted in order to explore the feasibility, safety and efficacy of preoperative chemotherapy for advanced gastric cancer patients with GOO.
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September-2015
Volume 3 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Jiao X and Jiao X: Investigation of the potential role of preoperative chemotherapy in treatment for gastric cancer with outlet obstruction. Mol Clin Oncol 3: 1177-1183, 2015
APA
Jiao, X., & Jiao, X. (2015). Investigation of the potential role of preoperative chemotherapy in treatment for gastric cancer with outlet obstruction. Molecular and Clinical Oncology, 3, 1177-1183. https://doi.org/10.3892/mco.2015.587
MLA
Jiao, X., Zhou, Y."Investigation of the potential role of preoperative chemotherapy in treatment for gastric cancer with outlet obstruction". Molecular and Clinical Oncology 3.5 (2015): 1177-1183.
Chicago
Jiao, X., Zhou, Y."Investigation of the potential role of preoperative chemotherapy in treatment for gastric cancer with outlet obstruction". Molecular and Clinical Oncology 3, no. 5 (2015): 1177-1183. https://doi.org/10.3892/mco.2015.587