Rare virilizing granulosa cell tumor in an adolescent

  • Authors:
    • Dorottya Bús
    • Mária Buzogány
    • Gyöngyi Nagy
    • György Vajda
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  • Published online on: November 18, 2016     https://doi.org/10.3892/mco.2016.1084
  • Pages: 88-90
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Abstract

Hormone‑producing malignancies are rare in children or adolescent patients: Only 0.1% of all ovarian tumors and 4-5% of granulosa cell tumors occur in the sexually non‑active ages. Granulosa cell tumors (GCTs) are sex cord‑stromal tumors of the ovary, representing 7-8% of all ovarian neoplasms. A total of 95% of all GCTs are adult‑type, and only 5% are diagnosed as juvenile‑type GCT. A majority of children with juvenile‑type GCT present with isosexual precocious pseudopuberty due to excessive estrogen production, although virilizing, testosterone‑producing, juvenile‑type GCTs are rare, occurring only in 2-3% of cases. The present case study reports on a case of a virilizing, juvenile‑type GCT in a 14-year-old girl, along with a review of the literature.
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January-2017
Volume 6 Issue 1

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Spandidos Publications style
Bús D, Buzogány M, Nagy G and Vajda G: Rare virilizing granulosa cell tumor in an adolescent. Mol Clin Oncol 6: 88-90, 2017.
APA
Bús, D., Buzogány, M., Nagy, G., & Vajda, G. (2017). Rare virilizing granulosa cell tumor in an adolescent. Molecular and Clinical Oncology, 6, 88-90. https://doi.org/10.3892/mco.2016.1084
MLA
Bús, D., Buzogány, M., Nagy, G., Vajda, G."Rare virilizing granulosa cell tumor in an adolescent". Molecular and Clinical Oncology 6.1 (2017): 88-90.
Chicago
Bús, D., Buzogány, M., Nagy, G., Vajda, G."Rare virilizing granulosa cell tumor in an adolescent". Molecular and Clinical Oncology 6, no. 1 (2017): 88-90. https://doi.org/10.3892/mco.2016.1084