Intramural chondroid hamartoma in the distal esophagus in an adult: A case report and review of the literature

Hou,Suping; Wei,Jianguo; Lu,Wenmin; Wang,Linna; Liu,Hongbo; Zhang,Qingquan

doi:10.3892/mco.2016.1095

Intramural chondroid hamartoma in the distal esophagus in an adult: A case report and review of the literature

Authors:
- Suping Hou
- Jianguo Wei
- Wenmin Lu
- Linna Wang
- Hongbo Liu
- Qingquan Zhang
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Affiliations: Department of Pathology, Harrison International Peace Hospital, Hengshui, Hebei 053000, P.R. China, Department of Pathology, Shaoxing People's Hospital, Shaoxing, Zhejiang 312000, P.R. China, Department of Thoracic Surgery, Harrison International Peace Hospital, Hengshui, Hebei 053000 P.R. China
Published online on: November 28, 2016 https://doi.org/10.3892/mco.2016.1095
Pages: 19-22
Copyright: © Hou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Hamartoma of the esophagus is a rare lesion and the number of cases reported in the literature to date is limited. The majority of hamartomas are intraluminal tumors located in the upper third of the esophagus. Histopathologically, the majority of these tumors comprise a mixture of adipose tissue, skeletal/smooth muscle tissue, vascular components and fibrous connective tissue. We herein present the case of a 33‑year‑old man with an intramural chondroid hamartoma located in the lower third of the esophagus. The patient underwent esophagotomy and the histopathological examination revealed that the tumor was mainly composed of chondroid tissue (60%) admixed with adipose tissue (25%) and fibrous connective tissue (15%). The aim of this study was to describe another variant of esophageal hamartoma, which exhibits a versatile phenotype.

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1	Choong CK and Meyers BF: Benign esophageal tumors: Introduction, incidence, classification and clinical features. Semin Thorac Cardiovasc Surg. 15:3–8. 2003. View Article : Google Scholar : PubMed/NCBI
2	Wu WM, Wang XD, Sun G, Qiang LH and Yang YS: Adult asymptomatic hamartoma in the distal esophagus: A rare case. Intern Med. 53:1945–1948. 2014. View Article : Google Scholar : PubMed/NCBI
3	Pilch BZ: Larynx and hypopharynxHead and Neck Surgical Pathology. Lippincott Williams and Wilkins; Philadelphia, PA: pp. 230–83. 2001
4	Barnes L: Surgical Pathology of the Head and Neck. 2. 2nd. Marcel Dekker; New York, NY: pp. 1649–1672. 2001
5	Kumar V, Abbas AK and Aster JC: Robbins Basic Pathology. 9th. Philadelphia, USA, Saunders: Elsevier; pp. 2572013
6	Allon I, Allon DM, Hirshberg A, Shlomi B, Lifschitz-Mercer B and Kaplan I: Oral neurovascularhamartoma: A lesion searching for a name. J Oral Pathol Med. 41:348–353. 2012. View Article : Google Scholar : PubMed/NCBI
7	Umashankar T, Devadas AK, Ravichandra G and Yaranal PJ: Pulmonary hamartoma: Cytologicalstudy of a case and literature review. J Cytol. 29:261–263. 2012. View Article : Google Scholar : PubMed/NCBI
8	Rosado E, Cabral P, Campo M and Tavares A: Mesenchymal hamartoma of the liver-a case report and literature review. J Radiol Case Rep. 7:35–43. 2013.PubMed/NCBI
9	Kawakami F, Shimizu M, Yamaguchi H, Hara S, Matsumoto I, Ku Y and Itoh T: Multiple solid pancreatic hamartomas: A case report and review of the literature. World J Gastrointest Oncol. 4:202–206. 2012. View Article : Google Scholar : PubMed/NCBI
10	Basso SM, Sulfaro S, Marzano B, Fanti G, Chiara GB and Lumachi F: Incidentally discovered asymptomatic splenic hamartoma with rapidly expansive growth: A case report. In Vivo. 26:1049–1052. 2012.PubMed/NCBI
11	Smith CW, Murray GF and Wilcox BR: Intramural esophageal hamartoma. An unusual cause of progressive stricture in a child. J Thorac Cardiovasc Surg. 72:315–318. 1976.PubMed/NCBI
12	Park SK, Jung H and Yang YI: Mesenchymal hamartoma in nasopharynx: A case report. Auris Nasus Larynx. 35:437–439. 2008. View Article : Google Scholar : PubMed/NCBI
13	Fan M, Lin Y and Liu L: Multiple pulmonary chondroid hamartoma. J Thorac Oncol. 9:11053–11054. 2014. View Article : Google Scholar
14	Scheele J, Lemke J, Barth TF, Juchems M, Wittau M, Kornmann M and Henne-Bruns D: Chondroid hamartoma of the liver. GMS Interdiscip Plast Reconstr Surg DGPW. 17:Doc162014.
15	Dorland and Newman WA: Dorland's illustrated medical dictionary. 32nd. Elsevier/Saunders; Philadelphia: 2012
16	Fuller AP: Pedunculated hamartoma of the oesophagus. J Laryngol Otol. 77:706–713. 1963. View Article : Google Scholar : PubMed/NCBI
17	Shah B, Unger L and Heimlich HJ: Hamartomatous polyp of the esophagus. Arch Surg. 110:326–328. 1975. View Article : Google Scholar : PubMed/NCBI
18	Beckerman RC, Taussig LM, Froede RC, Coulthard SW, Firor H and Tonkin I: Fibromuscular hamartoma of the esophagus in an infant. Am J Dis Child. 134:153–155. 1980.PubMed/NCBI
19	Venn GE, DaCosta P and Goldstraw P: Giant oesophageal hamartoma. Thorax. 40:684–685. 1985. View Article : Google Scholar : PubMed/NCBI
20	Gupta AK, Goyal VP, Hemani DD, Maheshwari SK and Dubey MK: Pedunculated intraluminal oesophageal hamartoma. J Laryngol Otol. 101:851–854. 1987. View Article : Google Scholar : PubMed/NCBI
21	Saitoh Y, Inomata Y, Tadaki N and Mimaki S: Pedunculated intraluminal osteochrondromatous hamartoma of the esophagus. J Otolaryngol. 19:339–342. 1990.PubMed/NCBI
22	Lakhkar BN, Ghosh MK, Shenoy PD and Patil UD: Hamartoma-a benign intraluminal tumor of the oesophagus (a case report). J Postgrad Med. 37:235–237, 236A-236B. 1991.PubMed/NCBI
23	Halfhide BC, Ginai AZ, Spoelstra HA, Dees J and Vuzevski VD: Case report: A hamartoma presenting as a giant oesophageal polyp. Br J Radiol. 68:85–88. 1995. View Article : Google Scholar : PubMed/NCBI
24	Kafai F and Mirbod P: Hamartoma of the oesophagus. Br J Clin Pract. 31:154–156. 1977.PubMed/NCBI
25	Bernat M, Strutyńska-Karpinska M, Lewandowski A, Blaszczuk J, Grabowski K and Czapla L: Benign esophageal tumors. Wiad Lek. 46:24–27. 1993.(In Polish). PubMed/NCBI