Metastatic prostate cancer initially presenting as chylothorax: A case report

Yang,Yu‑Jin; Seo,Minjung; Jeon,Hee‑Jeong; Noh,Jin‑Hee; Park,Seol Hoon; Choi,Yunsuk; Jo,Jae‑Cheol; Baek,Jin Ho; Koh,Su‑Jin; Kim,Hawk; Min,Young Joo

doi:10.3892/mco.2016.825

Metastatic prostate cancer initially presenting as chylothorax: A case report

Authors:
- Yu‑Jin Yang
- Minjung Seo
- Hee‑Jeong Jeon
- Jin‑Hee Noh
- Seol Hoon Park
- Yunsuk Choi
- Jae‑Cheol Jo
- Jin Ho Baek
- Su‑Jin Koh
- Hawk Kim
- Young Joo Min
View Affiliations

Affiliations: Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea, Department of Nuclear Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea, Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea
Published online on: March 21, 2016 https://doi.org/10.3892/mco.2016.825
Pages: 1009-1012

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Chylothorax is caused by disruption or obstruction of the thoracic duct, which results in leakage of chyle in the pleural space. The most common etiologies are malignancy and trauma. Among the causative malignancies, lymphoma is the most common, followed by primary lung cancer, mediastinal tumors, and other metastatic malignancies. Conversely, prostate cancer has rarely been reported as the cause of chylothorax. We herein report a case of metastatic prostate cancer initially presenting as chylothorax, with disappearance of the pleural effusion after the initiation of androgen deprivation therapy. Moreover, we also discuss the various rare manifestations of metastatic prostate cancer, including chylothorax.

View Figures

View References

1	Siegel R, Ma J, Zou Z and Jemal A: Cancer statistics, 2014. CA Cancer J Clin. 64:9–29. 2014. View Article : Google Scholar : PubMed/NCBI
2	Elkin M and Mueller HP: Metastases from cancer of the prostate; Autopsy and roentgenological findings. Cancer. 7:1246–1248. 1954. View Article : Google Scholar : PubMed/NCBI
3	Jung KW, Won YJ, Kong HJ, Oh CM, Lee DH and Lee JS: Cancer statistics in Korea: Incidence, mortality, survival and prevalence in 2011. Cancer Res Treat. 46:109–123. 2014. View Article : Google Scholar : PubMed/NCBI
4	Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Ciatto S, Nelen V, Kwiatkowski M, Lujan M, Lilja H, Zappa M, et al: Screening and prostate-cancer mortality in a randomized European study. N Engl J Med. 360:1320–1328. 2009. View Article : Google Scholar : PubMed/NCBI
5	Loeb S: Guideline of guidelines: Prostate cancer screening. BJU Int. 114:323–325. 2014.PubMed/NCBI
6	Crawford ED: Epidemiology of prostate cancer. Urology. 62(6 Suppl 1): 3–12. 2003. View Article : Google Scholar : PubMed/NCBI
7	Mak G, Chin M, Nahar N and De Souza P: Cutaneous metastasis of prostate carcinoma treated with radiotherapy: A case presentation. BMC Res Notes. 7:5052014. View Article : Google Scholar : PubMed/NCBI
8	Garai S and Pandey U: Prostate cancer presenting as an endobronchial mass: A case report with literature review. Int J Surg Pathol. 18:554–556. 2010.PubMed/NCBI
9	Ani I, Costaldi M and Abouassaly R: Metastatic prostate cancer with malignant ascites: A case report and literature review. Can Urol Assoc J. 7:E248–E250. 2013. View Article : Google Scholar : PubMed/NCBI
10	Sakata R, Iwasaki A, Kobayashi M, Osaka K, Fujikawa A, Tsuchiya F and Ishizuka E: Renal metastasis from prostatic adenocarcinoma: A case report. ACTA UROLOGICA JAPONICA. 57:683–687. 2011.(In Japanese). PubMed/NCBI
11	Ibinaiye PO, Mbibu H, Shehu SM, David SO and Samaila MO: Renal metastasis from prostate adenocarcinoma: A potential diagnostic pitfall. Ann Afr Med. 11:230–233. 2012. View Article : Google Scholar : PubMed/NCBI
12	Grenader T, Shavit L, Lossos A, Pizov G and Wygoda M: Brain metastases: A rare initial presentation of prostate cancer. Int Urol Nephrol. 39:537–539. 2007. View Article : Google Scholar : PubMed/NCBI
13	Rahmathulla G, Prayson RA and Weil RJ: Rare presentation of metastatic prostate adenocarcinoma as a meningioma mimic. J Neurol Surg Rep. 75:e81–e83. 2014. View Article : Google Scholar : PubMed/NCBI
14	Patel N, Teh BS, Powell S, Lu HH, Amato R and Butler EB: Rare case of metastatic prostate adenocarcinoma to the pituitary. Urology. 62:3522003. View Article : Google Scholar : PubMed/NCBI
15	Kaswala DH, Patel N, Jadallah S and Wang W: Metastatic prostate cancer to the duodenum: A rare case. J Family Med Prim Care. 3:166–168. 2014. View Article : Google Scholar : PubMed/NCBI
16	Kusaka A, Koie T, Yamamoto H, Hamano I and Yoneyama T, Hashimoto Y, Ohyama C, Tobisawa Y and Yoneyama T: Testicular metastasis of prostate cancer: A case report. Case Rep Oncol. 7:643–647. 2014. View Article : Google Scholar : PubMed/NCBI
17	Mortensen MA, Engvad B, Geertsen L, Svolgaard N and Lund L: Metastasis in testis from prostate cancer. Ugeskr Laeger. 176:V101306322014.(In Danish). PubMed/NCBI
18	Tabba M and Inaty H: A rare case of chylothorax attributed to metastatic prostate carcinoma. J Pulmon Resp Med. S142013.
19	Quinonez A, Halabe J, Avelar F, Lifshitz A, Moreno J and Berumen AH: Chylothorax due to metastatic prostatic carcinoma. Br J Urol. 63:325–327. 1989. View Article : Google Scholar : PubMed/NCBI
20	Pui MH and Yueh TC: Lymphoscintigraphy in chyluria, chyloperitoneum and chylothorax. J Nucl Med. 39:1292–1296. 1998.PubMed/NCBI
21	Prevot N, Tiffet O, Avet J Jr, Quak E, Decousus M and Dubois F: Lymphoscintigraphy and SPECT/CT using 99mTc filtered sulphur colloid in chylothorax. Eur J Nucl Med Mol Imaging. 38:17462011. View Article : Google Scholar : PubMed/NCBI
22	McLeod DG: Hormonal therapy: Historical perspective to future directions. Urology. 61(2 Suppl 1): 3–7. 2003. View Article : Google Scholar : PubMed/NCBI
23	Seidenfeld J, Samson DJ, Hasselblad V, Aronson N, Albertsen PC, Bennett CL and Wilt TJ: Single-therapy androgen suppression in men with advanced prostate cancer: A systematic review and meta-analysis. Ann Intern Med. 132:566–577. 2000. View Article : Google Scholar : PubMed/NCBI
24	Abrahamsson PA: Potential benefits of intermittent androgen suppression therapy in the treatment of prostate cancer: A systematic review of the literature. Eur Urol. 57:49–59. 2010. View Article : Google Scholar : PubMed/NCBI