Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature

Li,Yong; Lou,Jinrong; Qiu,Shujun; Guo,Yutian; Pan,Mianshun

doi:10.3892/mco.2016.922

Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature

Authors:
- Yong Li
- Jinrong Lou
- Shujun Qiu
- Yutian Guo
- Mianshun Pan
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Affiliations: Center of Radiation Oncology, Wujing Hospital, Shanghai 201103, P.R. China, Department of Internal Medicine, Jiading Central Hospital, Shanghai 201800, P.R. China
Published online on: June 8, 2016 https://doi.org/10.3892/mco.2016.922
Pages: 371-374

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Abstract

Cases of hypoglossal schwannoma are extremely rare. Historically, microsurgical resection has been the standard treatment, but it may not always be feasible; thus, it is crucial to investigate alternative treatments. We herein present the cases of two patients, both of whom presented with tongue deviation and hemiatrophy, accompanied by headaches. Magnetic resonance imaging revealed a dumbbell‑shaped tumor originating from the hypoglossal nerve that was adjacent to the cranial base in each patient. Hypofractionated stereotactic radiotherapy was used to treat the tumors, with a total dose of 30 Gy in 3-Gy fractions delivered to the planning target volume. Several months later, the tumors had significantly decreased in size and the symptoms of the two patients had gradually improved.

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