Pulmonary chondroma: A clinicopathological study of 29 cases and a review of the literature
- Authors:
- Dong Tian
- Hongying Wen
- Yu Zhou
- Maoyong Fu
View Affiliations
Affiliations: Department of Cardiothoracic Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China
- Published online on: July 1, 2016 https://doi.org/10.3892/mco.2016.945
-
Pages:
211-215
-
Copyright: © Tian
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License.
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
The present retrospective study was designed to review the clinicopathological features and outcome of surgical treatment of pulmonary chondroma, and to accumulate data for the clinical diagnosis and therapy. The clinicopathological data from 29 patients, aged between 38‑ and 78‑years‑old, with pulmonary chondroma who underwent surgical operation between July 2003 and June 2015 were reviewed. Of these patients, 18 exhibited no clinical symptoms, 7 were characterized by coughing, hemoptysis, shortness of breath and other symptoms and only 3 patients exhibited chest pain as the predominant symptom. The average size of the neoplasms was 3.6 cm. All patients were pathologically diagnosed. Operative time was 126±22 min, the mean intraoperative blood loss was 82±23 ml and the drainage duration was 3.1±1.8 days. A total of 6 postoperative complications were noted. The patients were followed‑up for 2‑135 months. A total of 23 patients were alive without recurrence, 4 patients succumbed to mortality, 2 patients were lost at follow‑up. Pulmonary chondroma is a rare benign tumor of the lung. The clinical symptoms were concealed and often misdiagnosed as a tuberculosis tumor, hamartoma, peripheral lung cancer or a single metastatic tumor. Complete resection was the best treatment providing patients with a good prognosis. After definite diagnosis, it is necessary to exclude Carney's triad.
View References
1
|
Ishii H, Akiba T, Marushima H, Kanetsuna Y
and Morikawa T: A case of bilateral multiple pulmonary chondroma:
Necessity of follow-up for Carney's triad. Gen Thorac Cardiovasc
Surg. 60:534–536. 2012. View Article : Google Scholar : PubMed/NCBI
|
2
|
Hoekstra MO, Bertus PM, Nikkels PG and
Kimpen JL: Multiple pulmonary chondromata. A rare cause of neonatal
respiratory distress. Chest. 105:301–302. 1994. View Article : Google Scholar : PubMed/NCBI
|
3
|
Bateson EM: Histogenesis of intrapulmonary
and endobronchial hamartomas and chondromas (cartilage-containing
tumours): A hypothesis. J Pathol. 101:77–83. 1970. View Article : Google Scholar : PubMed/NCBI
|
4
|
Rodriguez FJ, Aubry MC, Tazelaar HD,
Slezak J and Carney JA: Pulmonary chondroma: A tumor associated
with Carney triad and different from pulmonary hamartoma. Am J Surg
Pathol. 31:1844–1853. 2007. View Article : Google Scholar : PubMed/NCBI
|
5
|
Carney JA: Gastric stromal sarcoma,
pulmonary chondroma, and extra-adrenal paraganglioma (Carney
Triad): Natural history, adrenocortical component, and possible
familial occurrence. Mayo Clin Proc. 74:543–552. 1999. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ammar A, El Hammami S and Sellami Kamoun
N: Chondromas-a rare lung tumour: Rev Mal Respir. 22:826–827.
2005.(In French).
|
7
|
Silva VA, Kataguiri P, Trufelli DC, Matos
LL, Neves-Pereira JC and Campos JR: Pulmonary hamartoma as a
differential diagnosis of breast cancer metastasis: Case report. J
Bras Pneumol. 33:738–742. 2007.(In Portuguese). View Article : Google Scholar : PubMed/NCBI
|
8
|
Allan JS: Rare solitary benign tumors of
the lung. Semin Thorac Cardiovasc Surg. 15:315–322. 2003.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Carney JA, Sheps SG, Go VL and Gordon H:
The triad of gastric leiomyosarcoma, functioning extra-adrenal
paraganglioma and pulmonary chondroma. N Engl J Med. 296:1517–1518.
1977. View Article : Google Scholar : PubMed/NCBI
|
10
|
Zhang L, Smyrk TC, Young WF Jr, Stratakis
CA and Carney JA: Gastric stromal tumors in Carney triad are
different clinically, pathologically, and behaviorally from
sporadic gastric gastrointestinal stromal tumors: Findings in 104
cases. Am J Surg Pathol. 34:53–64. 2010. View Article : Google Scholar : PubMed/NCBI
|
11
|
Strano S, Ouafi L, Baud M and Alifano M:
Primary chordoma of the lung. Ann Thorac Surg. 89:302–303. 2010.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Fain O: Pulmonary tuberculoma. Rev Prat.
55:17512005.(In French). PubMed/NCBI
|
13
|
Dragoumis DM, Boudalaki ES, Assimaki AS
and Tsiftsoglou AP: Pulmonary hamartoma masquerading lung
metastasis in a woman with inflammatory breast cancer. Breast J.
18:486–488. 2012. View Article : Google Scholar : PubMed/NCBI
|
14
|
Yokota H, Shigeta A, Edo H and Niijima M:
Peripheral lung cancer effectively diagnosed with virtual
bronchoscopy. Nihon Naika Gakkai Zasshi. 96:781–783. 2007.(In
Japanese). View Article : Google Scholar : PubMed/NCBI
|
15
|
Mei B, Lai YL, He GJ, Shou YN and Liu J:
Giant primary mesenchymal chondrosarcoma of the lung: Case report
and review of literature. Ann Thorac Cardiovasc Surg. 19:481–484.
2013. View Article : Google Scholar : PubMed/NCBI
|
16
|
Ludwig C, Zeitoun M and Stoelben E:
Video-assisted thoracoscopic resection of pulmonary lesions. Eur J
Surg Oncol. 30:1118–1122. 2004. View Article : Google Scholar : PubMed/NCBI
|