Tuberous sclerosis-associated renal angiomyolipoma: A report of two cases and review of the literature

Lin,Canbin; Jin,Lu; Yang,Yu; Ding,Yu; Wu,Xionghui; Ni,Liangchao; Yang,Shangqi; Lai,Yongqing

doi:10.3892/mco.2017.1377

Tuberous sclerosis-associated renal angiomyolipoma: A report of two cases and review of the literature

Authors:
- Canbin Lin
- Lu Jin
- Yu Yang
- Yu Ding
- Xionghui Wu
- Liangchao Ni
- Shangqi Yang
- Yongqing Lai
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Affiliations: Department of Urology, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China, Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China
Published online on: August 14, 2017 https://doi.org/10.3892/mco.2017.1377
Pages: 706-708

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Abstract

In the general population, tuberous sclerosis‑associated renal angiomyolipoma (RAML) is a rare benign hamartoma with potentially life‑threatening complications and a poor prognosis. The two patients reported in the present study, who were diagnosed with bilateral RAML and spontaneous rupture of the RAML with tuberous sclerosis, presented with flank pain, abdominal pain, hemorrhage, hematuria and multiple lesions. The two cases are representative examples of the disease, and highlight the importance of determining the risk of acute hemorrhage in the early stages, and the significance of timely and proper treatment.

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