Association between genetic polymorphisms of long non‑coding RNA PRNCR1 and prostate cancer risk in a sample of the Iranian population
- Authors:
- Hedieh Sattarifard
- Mohammad Hashemi
- Shekoofeh Hassanzarei
- Behzad Narouie
- Gholamreza Bahari
-
Affiliations: Cellular and Molecular Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan 98167‑43181, Iran, Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan 98167‑43181, Iran, Urology and Nephrology Research Center, Department of Urology, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran 198396‑3113, Iran - Published online on: October 18, 2017 https://doi.org/10.3892/mco.2017.1462
- Pages: 1152-1158
This article is mentioned in:
Abstract
Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin. 61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI | |
Hsing AW and Devesa SS: Trends and patterns of prostate cancer: What do they suggest? Epidemiol Rev. 23:3–13. 2001. View Article : Google Scholar : PubMed/NCBI | |
Huang Q, Whitington T, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, et al: A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding. Nat Genet. 46:126–135. 2014. View Article : Google Scholar : PubMed/NCBI | |
Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL and Coetzee SG: Ellipse/GAME-ON consortium; Practical consortium, Henderson BE, Noushmehr H, et al: Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet. 10:e10041022014. View Article : Google Scholar : PubMed/NCBI | |
Spisák S, Lawrenson K, Fu Y, Csabai I, Cottman RT, Seo JH, Haiman C, Han Y, Lenci R, Li Q, et al: CAUSEL: An epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants. Nat Med. 21:1357–1363. 2015. View Article : Google Scholar : PubMed/NCBI | |
Chen H, Yu H, Wang J, Zhang Z, Gao Z, Chen Z, Lu Y, Liu W, Jiang D, Zheng SL, et al: Systematic enrichment analysis of potentially functional regions for 103 prostate cancer risk-associated loci. Prostate. 75:1264–1276. 2015. View Article : Google Scholar : PubMed/NCBI | |
ENCODE Project Consortium, . Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, et al: Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 447:799–816. 2007. View Article : Google Scholar : PubMed/NCBI | |
Groß S, Immel UD, Klintschar M and Bartel F: Germline genetics of the p53 pathway affect longevity in a gender specific manner. Curr Aging Sci. 7:91–100. 2014. View Article : Google Scholar : PubMed/NCBI | |
Kino T, Hurt DE, Ichijo T, Nader N and Chrousos GP: Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal. 3:ra82010. View Article : Google Scholar : PubMed/NCBI | |
Brannan CI, Dees EC, Ingram RS and Tilghman SM: The product of the H19 gene may function as an RNA. Mol Cell Biol. 10:28–36. 1990. View Article : Google Scholar : PubMed/NCBI | |
Chen B, Yu M, Chang Q, Lu Y, Thakur C, Ma D, Yi Z and Chen F: Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin. Oncotarget. 4:1427–1437. 2013. View Article : Google Scholar : PubMed/NCBI | |
Ma L, Bajic VB and Zhang Z: On the classification of long non-coding RNAs. RNA Biol. 10:925–933. 2013. View Article : Google Scholar : PubMed/NCBI | |
Fatica A and Bozzoni I: Long non-coding RNAs: New players in cell differentiation and development. Nat Rev Genet. 15:7–21. 2014. View Article : Google Scholar : PubMed/NCBI | |
Grote P and Herrmann BG: The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis. RNA Biol. 10:1579–1585. 2013. View Article : Google Scholar : PubMed/NCBI | |
Li Z and Rana TM: Decoding the noncoding: Prospective of lncRNA-mediated innate immune regulation. RNA Biol. 11:979–985. 2014. View Article : Google Scholar : PubMed/NCBI | |
Bartel DP: MicroRNAs: Target recognition and regulatory functions. Cell. 136:215–233. 2009. View Article : Google Scholar : PubMed/NCBI | |
Mattick JS: RNA regulation: A new genetics? Nat Rev Genet. 5:316–323. 2004. View Article : Google Scholar : PubMed/NCBI | |
Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, et al: The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression. Genome Res. 22:1775–1789. 2012. View Article : Google Scholar : PubMed/NCBI | |
Ponting CP, Oliver PL and Reik W: Evolution and functions of long noncoding RNAs. Cell. 136:629–641. 2009. View Article : Google Scholar : PubMed/NCBI | |
Lin R, Maeda S, Liu C, Karin M and Edgington TS: A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene. 26:851–858. 2007. View Article : Google Scholar : PubMed/NCBI | |
Pei Z, Du X, Song Y, Fan L, Li F, Gao Y, Wu R, Chen Y, Li W, Zhou H, et al: Down-regulation of lncRNA CASC2 promotes cell proliferation and metastasis of bladder cancer by activation of the Wnt/β-catenin signaling pathway. Oncotarget. 8:18145–18153. 2017.PubMed/NCBI | |
Li T, Xu C, Cai B, Zhang M, Gao F and Gan J: Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer. Oncol Lett. 12:4155–4160. 2016.PubMed/NCBI | |
He A, Chen Z, Mei H and Liu Y: Decreased expression of LncRNA MIR31HG in human bladder cancer. Cancer Biomark. 17:231–236. 2016. View Article : Google Scholar : PubMed/NCBI | |
Pibouin L, Villaudy J, Ferbus D, Muleris M, Prospéri MT, Remvikos Y and Goubin G: Cloning of the mRNA of overexpression in colon carcinoma-1: A sequence overexpressed in a subset of colon carcinomas. Cancer Genet Cytogenet. 133:55–60. 2002. View Article : Google Scholar : PubMed/NCBI | |
Calin GA, Liu CG, Ferracin M, Hyslop T, Spizzo R, Sevignani C, Fabbri M, Cimmino A, Lee EJ, Wojcik SE, et al: Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell. 12:215–229. 2007. View Article : Google Scholar : PubMed/NCBI | |
Chung S, Nakagawa H, Uemura M, Piao L, Ashikawa K, Hosono N, Takata R, Akamatsu S, Kawaguchi T, Morizono T, et al: Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility. Cancer Sci. 102:245–252. 2011. View Article : Google Scholar : PubMed/NCBI | |
Yang L, Lin C, Jin C, Yang JC, Tanasa B, Li W, Merkurjev D, Ohgi KA, Meng D, Zhang J, et al: lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs. Nature. 500:598–602. 2013. View Article : Google Scholar : PubMed/NCBI | |
Hui J, Xu Y, Yang K, Liu M, Wei D, Wei D, Zhang Y, Shi XH, Yang F, Wang N, et al: Study of genetic variants of 8q21 and 8q24 associated with prostate cancer in Jing-Jin residents in northern China. Clin Lab. 60:645–652. 2014. View Article : Google Scholar : PubMed/NCBI | |
Zheng SL, Hsing AW, Sun J, Chu LW, Yu K, Li G, Gao Z, Kim ST, Isaacs WB, Shen MC, et al: Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men. Prostate. 70:425–432. 2010.PubMed/NCBI | |
Salinas CA, Kwon E, Carlson CS, Koopmeiners JS, Feng Z, Karyadi DM, Ostrander EA and Stanford JL: Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 17:1203–1213. 2008. View Article : Google Scholar : PubMed/NCBI | |
Li L, Jia F, Bai P, Liang Y, Sun R, Yuan F, Zhang L and Gao L: Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of gastric cancer. Tumour Biol. 37:299–303. 2016. View Article : Google Scholar : PubMed/NCBI | |
He BS, Sun HL, Xu T, Pan YQ, Lin K, Gao TY, Zhang ZY and Wang SK: Association of genetic polymorphisms in the LncRNAs with gastric cancer risk in a Chinese population. J Cancer. 8:531–536. 2017. View Article : Google Scholar : PubMed/NCBI | |
Li L, Sun R, Liang Y, Pan X, Li Z, Bai P, Zeng X, Zhang D, Zhang L and Gao L: Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer. J Exp Clin Cancer Res. 32:1042013. View Article : Google Scholar : PubMed/NCBI | |
Chu H, Chen Y, Yuan Q, Hua Q, Zhang X, Wang M, Tong N, Zhang W, Chen J and Zhang Z: The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: A meta-analysis. Oncotarget. 8:43271–43283. 2017.PubMed/NCBI | |
Lv Z, Xu Q and Yuan Y: A systematic review and meta-analysis of the association between long non-coding RNA polymorphisms and cancer risk. Mutat Res. 771:1–14. 2017. View Article : Google Scholar : PubMed/NCBI | |
Hashemi M, Shahkar G, Simforoosh N, Basiri A, Ziaee SA, Narouie B and Taheri M: Association of polymorphisms in PRKCI gene and risk of prostate cancer in a sample of Iranian Population. Cell Mol Biol (Noisy-le-grand). 61:16–21. 2015.PubMed/NCBI | |
Hashemi M, Moradi N, Ziaee SA, Narouie B, Soltani MH, Rezaei M, Shahkar G and Taheri M: Association between single nucleotide polymorphism in miR-499, miR-196a2, miR-146a and miR-149 and prostate cancer risk in a sample of Iranian population. J Adv Res. 7:491–498. 2016. View Article : Google Scholar : PubMed/NCBI | |
Hashemi M, Danesh H, Bizhani F, Narouie B, Sotoudeh M, Nouralizadeh A, Sharifiaghdas F, Bahari G and Taheri M: Pri-miR-34b/c rs4938723 polymorphism increased the risk of prostate cancer. Cancer Biomark. 18:155–159. 2017. View Article : Google Scholar : PubMed/NCBI | |
Hashemi M, Bahari G, Sattarifard H and Narouie B: Evaluation of a 3-base pair indel polymorphism within pre-microRNA-3131 in patients with prostate cancer using mismatch polymerase chain reaction-restriction fragment length polymorphism. Mol Clin Oncol. 7:696–700. 2017.PubMed/NCBI | |
Solé X, Guinó E, Valls J, Iniesta R and Moreno V: SNPStats: A web tool for the analysis of association studies. Bioinformatics. 22:1928–1929. 2006. View Article : Google Scholar : PubMed/NCBI | |
Li L, Feng T, Lian Y, Zhang G, Garen A and Song X: Role of human noncoding RNAs in the control of tumorigenesis. Proc Natl Acad Sci USA. 106:pp. 12956–12961. 2009, View Article : Google Scholar : PubMed/NCBI | |
Zhang X, Rice K, Wang Y, Chen W, Zhong Y, Nakayama Y, Zhou Y and Klibanski A: Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: Isoform structure, expression, and functions. Endocrinology. 151:939–947. 2010. View Article : Google Scholar : PubMed/NCBI | |
Heemers HV and Tindall DJ: Androgen receptor (AR) coregulators: A diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev. 28:778–808. 2007. View Article : Google Scholar : PubMed/NCBI | |
Bahari G, Hashemi M, Naderi M and Taheri M: IKZF1 gene polymorphisms increased the risk of childhood acute lymphoblastic leukemia in an Iranian population. Tumour Biol. 37:9579–9586. 2016. View Article : Google Scholar : PubMed/NCBI | |
Hashemi M, Amininia S, Ebrahimi M, Simforoosh N, Basiri A, Ziaee SAM, Narouie B, Sotoudeh M, Mollakouchekian MJ, Rezghi Maleki E, et al: Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancer. Oncol Lett. 13:2483–2489. 2017.PubMed/NCBI | |
Bao BY, Lin VC, Yu CC, Yin HL, Chang TY, Lu TL, Lee HZ, Pao JB, Huang CY, Huang SP, et al: Genetic variants in ultraconserved regions associate with prostate cancer recurrence and survival. Sci Rep. 6:221242016. View Article : Google Scholar : PubMed/NCBI | |
Murali A, Varghese BT, Kumar RR and Kannan S: Combination of genetic variants in cyclin D1 and retinoblastoma genes predict clinical outcome in oral cancer patients. Tumour Biol. 37:3609–3617. 2016. View Article : Google Scholar : PubMed/NCBI | |
Kapranov P, Willingham AT and Gingeras TR: Genome-wide transcription and the implications for genomic organization. Nat Rev Genet. 8:413–423. 2007. View Article : Google Scholar : PubMed/NCBI | |
Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackermüller J, Hofacker IL, et al: RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science. 316:1484–1488. 2007. View Article : Google Scholar : PubMed/NCBI | |
Wu SW, Hao YP, Qiu JH, Zhang DB, Yu CG and Li WH: High expression of long non-coding RNA CCAT2 indicates poor prognosis of gastric cancer and promotes cell proliferation and invasion. Minerva Med. 108:317–323. 2017.PubMed/NCBI | |
Guo J, Ma J, Zhao G, Li G, Fu Y, Luo Y and Gui R: Long noncoding RNA LINC0086 functions as a tumor suppressor in nasopharyngeal carcinoma by targeting miR-214. Oncol Res. 25:1189–1197. 2017. View Article : Google Scholar : PubMed/NCBI | |
Liu JN and Shangguan YM: Long non-coding RNA CARLo-5 upregulation associates with poor prognosis in patients suffering gastric cancer. Eur Rev Med Pharmacol Sci. 21:530–534. 2017. View Article : Google Scholar : PubMed/NCBI | |
Yeager M, Chatterjee N, Ciampa J, Jacobs KB, Gonzalez-Bosquet J, Hayes RB, Kraft P, Wacholder S, Orr N, Berndt S, et al: Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet. 41:1055–1057. 2009. View Article : Google Scholar : PubMed/NCBI | |
Amundadottir LT, Sulem P, Gudmundsson J, Helgason A, Baker A, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Cazier JB, Sainz J, et al: A common variant associated with prostate cancer in European and African populations. Nat Genet. 38:652–658. 2006. View Article : Google Scholar : PubMed/NCBI | |
Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D, Helgason A, Rafnar T, Bergthorsson JT, Agnarsson BA, Baker A, et al: Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet. 39:631–637. 2007. View Article : Google Scholar : PubMed/NCBI | |
Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, Waliszewska A, Neubauer J, Tandon A, Schirmer C, McDonald GJ, et al: Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet. 39:638–644. 2007. View Article : Google Scholar : PubMed/NCBI | |
Eeles RA, Kote-Jarai Z, Giles GG, Olama AA, Guy M, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, et al: Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet. 40:316–321. 2008. View Article : Google Scholar : PubMed/NCBI | |
Al Olama AA, Kote-Jarai Z, Giles GG, Guy M, Morrison J, Severi G, Leongamornlert DA, Tymrakiewicz M, Jhavar S, Saunders E, et al: Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet. 41:1058–1060. 2009. View Article : Google Scholar : PubMed/NCBI | |
Keller C and Bühler M: Chromatin-associated ncRNA activities. Chromosome Res. 21:627–641. 2013. View Article : Google Scholar : PubMed/NCBI | |
Luco RF and Misteli T: More than a splicing code: Integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation. Curr Opin Genet Dev. 21:366–372. 2011. View Article : Google Scholar : PubMed/NCBI | |
Pircher A, Gebetsberger J and Polacek N: Ribosome-associated ncRNAs: An emerging class of translation regulators. RNA Biol. 11:1335–1339. 2014. View Article : Google Scholar : PubMed/NCBI | |
Hannon GJ: RNA interference. Nature. 418:244–251. 2002. View Article : Google Scholar : PubMed/NCBI | |
Lee JT: Epigenetic regulation by long noncoding RNAs. Science. 338:1435–1439. 2012. View Article : Google Scholar : PubMed/NCBI | |
Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, et al: Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci USA. 106:pp. 11667–11672. 2009, View Article : Google Scholar : PubMed/NCBI | |
Mercer TR, Dinger ME, Sunkin SM, Mehler MF and Mattick JS: Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci USA. 105:pp. 716–721. 2008, View Article : Google Scholar : PubMed/NCBI | |
Geisler S and Coller J: RNA in unexpected places: Long non-coding RNA functions in diverse cellular contexts. Nat Rev Mol Cell Biol. 14:699–712. 2013. View Article : Google Scholar : PubMed/NCBI | |
Spizzo R, Almeida MI, Colombatti A and Calin GA: Long non-coding RNAs and cancer: A new frontier of translational research? Oncogene. 31:4577–4587. 2012. View Article : Google Scholar : PubMed/NCBI | |
Tsai MC, Spitale RC and Chang HY: Long intergenic noncoding RNAs: New links in cancer progression. Cancer Res. 71:3–7. 2011. View Article : Google Scholar : PubMed/NCBI | |
Heemers H, Maes B, Foufelle F, Heyns W, Verhoeven G and Swinnen JV: Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway. Mol Endocrinol. 15:1817–1828. 2001. View Article : Google Scholar : PubMed/NCBI | |
Yang L, Qiu M, Xu Y, Wang J, Zheng Y, Li M, Xu L and Yin R: Upregulation of long non-coding RNA PRNCR1 in colorectal cancer promotes cell proliferation and cell cycle progression. Oncol Rep. 35:318–324. 2016. View Article : Google Scholar : PubMed/NCBI |