Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature

Larbcharoensub,Noppadol; Pangpunyakulchai,Duangjai; Aroonroch,Rangsima; Tuntiyatorn,Lojana; Mahaisavariya,Pornchai

doi:10.3892/mco.2017.1488

Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature

Authors:
- Noppadol Larbcharoensub
- Duangjai Pangpunyakulchai
- Rangsima Aroonroch
- Lojana Tuntiyatorn
- Pornchai Mahaisavariya
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Affiliations: Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok 10400, Thailand, Department of Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok 10400, Thailand, Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok 10400, Thailand
Published online on: November 3, 2017 https://doi.org/10.3892/mco.2017.1488
Pages: 209-213

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Abstract

Myoepithelial carcinoma is an uncommon malignant tumor of the lacrimal gland, composed of neoplastic myoepithelial cells with an infiltrative growth. The present study describes a unique case of progressive proptosis and blindness of the right eye in a 68‑year‑old woman following total tumor removal for lacrimal pleomorphic adenoma. Clinical study, surgical exploration, and pathology revealed lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma, T2N0M0. In addition, 18 cases of lacrimal myoepithelial tumor that have been previously described in the literature are reviewed. The application of clinical, radiological, histopathologic, and immunohistochemical investigations may help to reach the definite diagnosis. Criteria for malignancy of lacrimal myoepithelial tumor should be the same as salivary myoepithelial tumor diagnosis, until long‑term outcome data for a larger number of patients with lacrimal myoepithelial carcinoma become available.

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