Palmar fasciitis with polyarthritis-associated ovarian cancer: Case report and literature review

Kajikawa,Hiroyuki; Sobajima,Takuya; Koiwai,Chinatsu; Ichigo,Satoshi; Takagi,Hiroshi; Imai,Atsushi

doi:10.3892/mco.2017.1509

Palmar fasciitis with polyarthritis-associated ovarian cancer: Case report and literature review

Authors:
- Hiroyuki Kajikawa
- Takuya Sobajima
- Chinatsu Koiwai
- Satoshi Ichigo
- Hiroshi Takagi
- Atsushi Imai
View Affiliations

Affiliations: Department of Obstetrics and Gynecology, Matsunami General Hospital, Kasamatsu, Gifu 501‑6062, Japan, Department of General Internal Medicine, Matsunami General Hospital, Kasamatsu, Gifu 501‑6062, Japan
Published online on: November 24, 2017 https://doi.org/10.3892/mco.2017.1509
Pages: 292-295

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Palmar fasciitis and polyarthritis (PFPA) is an uncommon disorder clinically characterized by rapidly developing bilateral arthritis of the hands and fasciitis of the palms. This cancer‑associated syndrome, primarily linked to ovarian cancer, has also been associated with multiple different malignancies. PFPA symptoms usually precede the detection of ovarian cancer. In all patients from case series and single case reports described, ovarian cancer is already present at an advanced stage. Therefore, the authors aimed to present a case and systematically review available evidence on the association between PFPA and ovarian cancer, as gynecological oncologists. Awareness and recognition of PFPA may allow for earlier diagnosis and treatment of an occult ovarian cancer. The commitment of the attending gynecologists to become familiar with and identify rare diseases may lead to the detection at an early and curative stage and potentially life‑saving therapeutic interventions.

View Figures

View References

1	Champion GD, Saxon JA and Kossard S: The syndrome of palmar fibromatosis (fasciitis) and polyarthritis. J Rheumatol. 14:1196–1198. 1987.PubMed/NCBI
2	Alexandroff AB, Hazleman BL, Matthewson M, Black CM, Rytina E, Crawford R and Burrows NP: Woody hands. Lancet. 361:13442003. View Article : Google Scholar : PubMed/NCBI
3	Haroon M and Phelan M: A paraneoplastic case of palmar fasciitis and polyarthritis syndrome. Nat Clin Pract Rheumatol. 4:274–277. 2008. View Article : Google Scholar : PubMed/NCBI
4	Azar L and Khasnis A: Paraneoplastic rheumatologic syndromes. Curr Opin Rheumatol. 25:44–49. 2013. View Article : Google Scholar : PubMed/NCBI
5	Baron M: Palmar fasciitis, polyarthritis and carcinoma. Ann Intern Med. 97:6161982. View Article : Google Scholar : PubMed/NCBI
6	Manger B and Schett G: Palmar fasciitis and polyarthritis syndrome-systematic literature review of 100 cases. Semin Arthritis Rheum. 44:105–111. 2014. View Article : Google Scholar : PubMed/NCBI
7	Qureshi AA and Saavedra A: Palmar fasciitis and polyarthritis syndrome in patients with ovarian cancer-a case report and review of the literature. Hand(N Y). 6:220–223. 2011. View Article : Google Scholar : PubMed/NCBI
8	Scheinfeld N: A review of the cutaneous paraneoplastic associations and metastatic presentations of ovarian carcinoma. Clin Exp Dermatol. 33:10–15. 2008.PubMed/NCBI
9	Denschlag D, Riener E, Vaith P, Tempfer C and Keck C: Palmar fasciitis and polyarthritis as a paraneoplastic syndrome associated with tubal carcinoma: A case report. Ann Rheum Dis. 63:1177–1178. 2004. View Article : Google Scholar : PubMed/NCBI
10	Taggart AJ, Iveson JM and Wright V: Shoulder-hand syndrome and symmetrical arthralgia in patients with tubo-ovarian carcinoma. Ann Rheum Dis. 43:391–393. 1984. View Article : Google Scholar : PubMed/NCBI
11	Fukui S, Fujiwara S, Kobayashi S, Kamei S, Takizawa Y, Setoguchi K, Uno M and Funata N: Fallopian tube cancer with palmar fibromatosis or fasciitis without polyarthritis. Intern Med. 54:2409–2414. 2015. View Article : Google Scholar : PubMed/NCBI
12	Carlson JW, Miron A, Jarboe EA, Parast MM, Hirsch MS, Lee Y, Muto MG, Kindelberger D and Crum CP: Serous tubal intraepithelial carcinoma: Its potential role in primary peritoneal serous carcinoma and serous cancer prevention. J Clin Oncol. 26:4160–4165. 2008. View Article : Google Scholar : PubMed/NCBI
13	Dietl J: Revisiting the pathogenesis of ovarian cancer: The central role of the fallopian tube. Arch Gynecol Obstet. 289:241–246. 2014. View Article : Google Scholar : PubMed/NCBI
14	Lee Y, Miron A, Drapkin R, Nucci MR, Medeiros F, Saleemuddin A, Garber J, Birch C, Mou H, Gordon RW, et al: A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol. 211:26–35. 2007. View Article : Google Scholar : PubMed/NCBI
15	Reade CJ, McVey RM, Tone AA, Finlayson SJ, McAlpine JN, Fung-Kee-Fung M and Ferguson SE: The fallopian tube as the origin of high grade serous ovarian cancer: Review of a paradigm shift. J Obstet Gynaecol Can. 36:133–140. 2014. View Article : Google Scholar : PubMed/NCBI
16	Preda V, Frederiksen P and Kossard S: Indurated reticulate palmar erythema as a sign of paraneoplastic palmar fasciitis and polyarthritis syndrome. Australas J Dermatol. 50:198–201. 2009. View Article : Google Scholar : PubMed/NCBI
17	Mehra S, Walker J, Patterson K and Fritzler MJ: Autoantibodies in systemic sclerosis. Autoimmun Rev. 12:340–354. 2013. View Article : Google Scholar : PubMed/NCBI
18	Emori C and Sugiura K: Role of oocyte-derived paracrine factors in follicular development. Anim Sci J. 85:627–633. 2014. View Article : Google Scholar : PubMed/NCBI
19	Geva E and Jaffe RB: Role of vascular endothelial growth factor in ovarian physiology and pathology. Fertil Steril. 74:429–438. 2000. View Article : Google Scholar : PubMed/NCBI
20	Imai A, Ichigo S, Matsunami K, Takagi H and Kawabata I: Ovarian function following targeted anti-angiogenic therapy with bevacizumab. Mol Clin Oncol. 6:807–810. 2017. View Article : Google Scholar : PubMed/NCBI
21	van Marcke C, Seront E, Docquier C and Filleul B: Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer. Clin Exp Dermatol. 42:328–330. 2017. View Article : Google Scholar : PubMed/NCBI
22	Fernandez-Nebro A, Fernandez-Ruiz A, Rodriguez M, Haro M, Rodriguez-Andreu J and Gonzalez-Santos P: Palmar fasciitis and polyarthritis syndrome is multicausal. Clin Rheumatol. 15:99–101. 1996. View Article : Google Scholar : PubMed/NCBI
23	Medsger TA, Dixon JA and Garwood VF: Palmar fasciitis and polyarthritis associated with ovarian carcinoma. Ann Intern Med. 96:424–431. 1982. View Article : Google Scholar : PubMed/NCBI
24	Martorell EA, Murray PM, Peterson JJ, Menke DM and Calamia KT: Palmar fasciitis and arthritis syndrome associated with metastatic ovarian carcinoma: A report of four cases. J Hand Surg Am. 29:1–660. 2004. View Article : Google Scholar : PubMed/NCBI
25	Yogarajah M, Soh J, Lord B, Goddard N and Stratton R: Palmar fasciitis and polyarthritis syndrome: A sign of ovarian malignancy. J R Soc Med. 101:473–475. 2008. View Article : Google Scholar : PubMed/NCBI
26	Strobel ES, Lacour M and Peter HH: Palmar fascial thickening and contractures of fingers resembling arthritis-a paraneoplastic symptom? Rheumatol Int. 12:79–80. 1992. View Article : Google Scholar : PubMed/NCBI
27	Salmon C, Gill G, Loeuille D and Chary-Valckenaere I: Three new cases of palmar fasciitis with polyarthritis including a patient with atypical mutilating osteolysis. Joint Bone Spine. 80:217–220. 2013. View Article : Google Scholar : PubMed/NCBI
28	Pfinsgraff J, Buckingham RB, Killian PJ, Keister SR, Brereton WF, Weinblatt ME, George DL and Arnett FC: Palmar fasciitis and arthritis with malignant neoplasms: A paraneoplastic syndrome. Semin Arthritis Rheum. 16:118–125. 1986. View Article : Google Scholar : PubMed/NCBI
29	Bremer C: Shoulder-hand syndrome. A case of unusual aetiology. Ann Phys Med. 9:168–171. 1967.PubMed/NCBI
30	Vinker S, Dgani R, Lifschitz-Mercer B, Sthoeger ZM and Green L: Palmar fasciitis and polyarthritis associated with ovarian carcinoma in a young patient. A case report and review of the literature. Clin Rheumatol. 15:495–497. 1996. View Article : Google Scholar : PubMed/NCBI
31	Shiel WJ, Prete PE, Jason M and Andrews BS: Palmar fasciitis and arthritis with ovarian and non-ovarian carcinomas. New syndrome. Am J Med. 79:640–644. 1985. View Article : Google Scholar : PubMed/NCBI