Osseous choristoma of the tongue: A case report with dermoscopic study

Yoshimura,Hitoshi; Ohba,Seigo; Imamura,Yoshiaki; Sano,Kazuo

doi:10.3892/mco.2017.1523

Osseous choristoma of the tongue: A case report with dermoscopic study

Authors:
- Hitoshi Yoshimura
- Seigo Ohba
- Yoshiaki Imamura
- Kazuo Sano
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Affiliations: Department of Dentistry and Oral Surgery, Unit of Sensory and Locomotor Medicine, Division of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910‑1193, Japan, Division of Surgical Pathology, University of Fukui Hospital, Fukui 910‑1193, Japan
Published online on: November 29, 2017 https://doi.org/10.3892/mco.2017.1523
Pages: 242-245
Copyright: © Yoshimura et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Osseous choristomas are rare benign lesions characterized by ectopic bone formation in the soft tissue of the head and neck region. Dermoscopy visualizes the morphological characteristics that are not observable by the naked eye, and may be used for the evaluation of calcification under the skin. The present study reports a case of an osseous choristoma arising in the tongue, and reveals the dermoscopic features of osseous choristoma from a surgical specimen. A 7‑year‑old boy was referred to the Department of Dentistry and Oral Surgery, with an asymptomatic pedunculated mass in the tongue. The lesion was removed completely with the adjacent normal tissue under general anesthesia. Dermoscopy of the surgical specimen revealed the hypovascular and homogeneous pattern of the lesion with round extruded whitish material. Based on dermoscopic findings, the presence of calcified hard tissue in the submucosa was verified by the dermatologist. Radiographic examination of the surgical specimen revealed the lesion contained a radiopaque trabeculated mass. Histologically, the lesion contained an osseous tissue, and the pathological diagnosis of osseous choristoma was made following consideration of the ectopic bony tissues that were localized away from the maxillo‑mandibular bone. The postoperative course was uneventful with no signs of recurrence during the 36 months following surgery. To the best of the author's knowledge, this is the first report of evaluation of osseous choristoma using dermoscopy. The observation indicates the usefulness of dermoscopy for the diagnosis of oral ossified lesion in oral soft tissue.

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1	Neville BW, Damm DD, Allen CM and Bouquot JE: Oral and Maxillofacial Pathology. 3rd. Saunders Elsevier; St. Louis: pp. 5522009
2	Chou LS, Hansen LS and Daniels TE: Choristomas of the oral cavity: A review. Oral Surg Oral Med Oral Pathol. 72:584–593. 1991. View Article : Google Scholar : PubMed/NCBI
3	Krolls SO, Jacoway JR and Alexander WN: Osseous choristomas (osteomas) of intraoral soft tissues. Oral Surg Oral Med Oral Pathol. 32:588–595. 1971. View Article : Google Scholar : PubMed/NCBI
4	Tohill MJ, Green JG and Cohen DM: Intraoral osseous and cartilaginous choristomas: Report of three cases and review of the literature. Oral Surg Oral Med Oral Pathol. 63:506–510. 1987. View Article : Google Scholar : PubMed/NCBI
5	Psimopoulou M and Antoniades K: Submental osseous choristoma: A case report. J Oral Maxillofac Surg. 56:666–667. 1998. View Article : Google Scholar : PubMed/NCBI
6	Dalkiz M, Hakan Yurdakul R, Pakdemirli E and Beydemir B: Recurrent osseous choristoma of the masseter muscle: Case report. J Oral Maxillofac Surg. 59:836–839. 2001. View Article : Google Scholar : PubMed/NCBI
7	Yamamoto N, Ishikawa A, Yamauchi K, Miyamoto I, Tanaka T, Kito S, Matsuo K, Yamashita Y, Morimoto Y and Takahashi T: Osteolipoma of the lower lip: A case report. Asian J Oral Maxillofac Surg. 23:143–145. 2011. View Article : Google Scholar
8	Russo T, Piccolo V, Lallas A and Argenziano G: Recent advances in dermoscopy. F1000Res. 5:1842016.
9	Lallas A, Zalaudek I, Argenziano G, Longo C, Moscarella E, Di Lernia V, Al Jalbout S and Apalla Z: Dermoscopy in general dermatology. Dermatol Clin. 31:679–694. 2013. View Article : Google Scholar : PubMed/NCBI
10	De Giorgi V, Massi D and Carli P: Dermoscopy in the management of pigmented lesions of the oral mucosa. Oral Oncol. 39:534–535. 2003. View Article : Google Scholar : PubMed/NCBI
11	Olszewska M, Banka A, Gorska R and Warszawik O: Dermoscopy of pigmented oral lesions. J Dermatol Case Rep. 2:43–48. 2008. View Article : Google Scholar : PubMed/NCBI
12	Strumia R: Videodermatoscopy: A useful tool for diagnosing cutaneous dystrophic calcifications. Dermatol Online J. 11:282005.PubMed/NCBI
13	Lallas A, Moscarella E, Argenziano G, Longo C, Apalla Z, Ferrara G, Piana S, Rosato S and Zalaudek I: Dermoscopy of uncommon skin tumours. Australas J Dermatol. 55:53–62. 2014. View Article : Google Scholar : PubMed/NCBI
14	Zaballos P, Llambrich A, Puig S and Malvehy J: Dermoscopic findings of pilomatricomas. Dermatology. 217:225–230. 2008. View Article : Google Scholar : PubMed/NCBI
15	Okamoto T, Sasaki R, Kataoka T, Kumasaka A, Kaibuchi N, Naganawa T, Fukada K and Ando T: Dermoscopy imaging findings in the normal Oral Mucosa. Oral Oncol. 51:e69–e70. 2015. View Article : Google Scholar : PubMed/NCBI
16	Warszawik-Hendzel O, Słowińska M, Olszewska M and Rudnicka L: Melanoma of the oral cavity: Pathogenesis, dermoscopy, clinical features, staging and management. J Dermatol Case Rep. 8:60–66. 2014. View Article : Google Scholar : PubMed/NCBI
17	Güleç AT: Dermoscopic features of squamous cell carcinoma of the tongue: It looks similar to cutaneous squamous cell carcinoma. J Am Acad Dermatol. 75:e53–e54. 2016. View Article : Google Scholar : PubMed/NCBI
18	Drogoszewska B, Chomik P, Polcyn A and Michcik A: Clinical diagnosis of oral erosive lichen planus by direct oral microscopy. Postepy Dermatol Alergol. 31:222–228. 2014. View Article : Google Scholar : PubMed/NCBI
19	Lee DL, Wong KT, Mak SM, Soo G and Tong MC: Lingual osteoma: Case report and literature review. Arch Otolaryngol Head Neck Surg. 135:308–310. 2009. View Article : Google Scholar : PubMed/NCBI
20	Yoshimura H, Ohba S, Matsuda S, Kobayashi J, Ishimaru K, Imamura Y and Sano K: Osseous choristoma of the buccal mucosa: A case report with immunohistochemical study of bone morphogenetic protein-2 and −4 and a review of the literature. J Oral Maxillofac Surg Med Pathol. 26:351–355. 2014. View Article : Google Scholar
21	Yamamoto M, Migita M, Ogane S, Narita M, Yamamoto N, Takaki T, Matsuzaka K and Shibahara T: Osseous choristoma in child with strong vomiting reflex. Bull Tokyo Dent Coll. 55:207–215. 2014. View Article : Google Scholar : PubMed/NCBI
22	Monserrat M: Ostéome de la langue. Bull Soc Anat. 88:282–283. 1913.
23	Church LE: Osteoma of the tongue. Report of a case. Oral Surg Oral Med Oral Pathol. 17:768–770. 1964. View Article : Google Scholar : PubMed/NCBI
24	Roy JJ, Klein HZ and Tipton DL: Osteochondroma of the tongue. Arch Pathol. 89:565–568. 1970.PubMed/NCBI
25	Xiao YT, Xiang LX and Shao JZ: Bone morphogenetic protein. Biochem Biophys Res Commun. 362:550–553. 2007. View Article : Google Scholar : PubMed/NCBI
26	Bragdon B, Moseychuk O, Saldanha S, King D, Julian J and Nohe A: Bone morphogenetic proteins: A critical review. Cell Signal. 23:609–620. 2011. View Article : Google Scholar : PubMed/NCBI
27	Kusumoto K, Bessho K, Fujimura K, Akioka J, Ogawa Y and Iizuka T: Comparison of ectopic osteoinduction in vivo by recombinant human BMP-2 and recombinant Xenopus BMP-4/7 heterodimer. Biochem Biophys Res Commun. 239:575–579. 1997. View Article : Google Scholar : PubMed/NCBI
28	Kim SY, Choi HY, Myung KB and Choi YW: The expression of molecular mediators in the idiopathic cutaneous calcification and ossification. J Cutan Pathol. 35:826–831. 2008. View Article : Google Scholar : PubMed/NCBI