Histiocytic sarcoma of the neck: A case report

  • Authors:
    • Jian Zhou
    • Yue Liu
    • Wanchun Wang
    • Feng-Lei Xu
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  • Published online on: April 26, 2018     https://doi.org/10.3892/mco.2018.1617
  • Pages: 54-57
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Abstract

Histiocytic sarcoma (HS) is a term used to describe malignant hyperplasia of cells exhibiting morphological and immunophenotypical characteristics similar to those of mature cells, with expression of one or more tissue cell markers, excluding acute monocytic leukemia and primitive monocytic sarcoma. We herein describe a case of histiocytic sarcoma of the neck supported by histopathological and immunohistological evidence. A 53-year-old female patient of Chinese descent presented with a rapidly enlarging right neck mass. Imaging studies revealed multiple right cervical lymphadenectases with right jugular vein involvement. The tumor was composed of diffusely distributed large non-cohesive tumor cells, round or oval and focally spindle-shaped. The tumor cells were immunopositive for macrophage-associated antigen CD68 and lysosomes, mostly consistent with a diagnosis of HS. HS is very prone to systemic metastasis; therefore, early diagnosis and timely treatment are crucial.
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July-2018
Volume 9 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Zhou J, Liu Y, Wang W and Xu F: Histiocytic sarcoma of the neck: A case report. Mol Clin Oncol 9: 54-57, 2018
APA
Zhou, J., Liu, Y., Wang, W., & Xu, F. (2018). Histiocytic sarcoma of the neck: A case report. Molecular and Clinical Oncology, 9, 54-57. https://doi.org/10.3892/mco.2018.1617
MLA
Zhou, J., Liu, Y., Wang, W., Xu, F."Histiocytic sarcoma of the neck: A case report". Molecular and Clinical Oncology 9.1 (2018): 54-57.
Chicago
Zhou, J., Liu, Y., Wang, W., Xu, F."Histiocytic sarcoma of the neck: A case report". Molecular and Clinical Oncology 9, no. 1 (2018): 54-57. https://doi.org/10.3892/mco.2018.1617