Open Access

Diffuse large B‑cell lymphoma with pulmonary and cerebral involvement: A case report

  • Authors:
    • Jing Zeng
    • Xiuqun Zhang
    • Wei Hua
    • Caiping Guo
    • Hao Wu
    • Ronghua Jin
    • Yulin Zhang
  • View Affiliations

  • Published online on: July 16, 2018     https://doi.org/10.3892/mco.2018.1673
  • Pages: 264-268
  • Copyright: © Zeng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary diffuse large B‑cell lymphoma (DLBCL) is the most common type of non‑Hodgkin lymphoma; however, the involvement of the lung and central nervous system (CNS) in patients with DLBCL is rare. Furthermore, patients with DLBCL rarely exhibit specific clinical symptoms, which may delay definitive diagnosis. The present study reports the case of a 42‑year‑old man suffering from primary DLBCL with concurrent pulmonary and cerebral involvement. The patient suffered from human immunodeficiency virus infection and presented with symptoms including dry cough, thoracalgia, intermittent mild fever and mild headache. Thoracic computed tomography scans revealed multiple pulmonary masses, and brain magnetic resonance imaging scans revealed nodules in the left frontal cortex and bilateral basal ganglia. A percutaneous lung needle biopsy test confirmed the diagnosis of DLBCL. In addition, positron emission tomography revealed the involvement of other parts of the body in DLBCL. The aim of the present study was to present the clinical, radiological and histological characteristics of the patient, which may aid physicians in diagnosing pulmonary and CNS involvement in DLBCL.
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September-2018
Volume 9 Issue 3

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
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Spandidos Publications style
Zeng J, Zhang X, Hua W, Guo C, Wu H, Jin R and Zhang Y: Diffuse large B‑cell lymphoma with pulmonary and cerebral involvement: A case report. Mol Clin Oncol 9: 264-268, 2018.
APA
Zeng, J., Zhang, X., Hua, W., Guo, C., Wu, H., Jin, R., & Zhang, Y. (2018). Diffuse large B‑cell lymphoma with pulmonary and cerebral involvement: A case report. Molecular and Clinical Oncology, 9, 264-268. https://doi.org/10.3892/mco.2018.1673
MLA
Zeng, J., Zhang, X., Hua, W., Guo, C., Wu, H., Jin, R., Zhang, Y."Diffuse large B‑cell lymphoma with pulmonary and cerebral involvement: A case report". Molecular and Clinical Oncology 9.3 (2018): 264-268.
Chicago
Zeng, J., Zhang, X., Hua, W., Guo, C., Wu, H., Jin, R., Zhang, Y."Diffuse large B‑cell lymphoma with pulmonary and cerebral involvement: A case report". Molecular and Clinical Oncology 9, no. 3 (2018): 264-268. https://doi.org/10.3892/mco.2018.1673