Open Access

The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer

  • Authors:
    • Chiyo Maeda
    • Shungo Endo
    • Yuichi Mori
    • Shumpei Mukai
    • Eiji Hidaka
    • Fumio Ishida
    • Shin-Ei Kudo
  • View Affiliations

  • Published online on: February 26, 2019     https://doi.org/10.3892/mco.2019.1815
  • Pages: 425-429
  • Copyright: © Maeda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Positron emission tomography/computed tomography (PET/CT) is frequently used to detect colorectal cancer. The present retrospective study assessed the ability of PET/CT to identify synchronous colonic lesions in 72 patients with obstructive colorectal cancer. All patients had undergone surgical resection without undergoing preoperative total colonoscopy (TCS) at the Digestive Disease Center (April 2007 to September 2016), and subsequently underwent TCS of the proximal colon within 2 years post‑surgery. A total of 11 patients exhibited 18F‑fluorodeoxyglucose uptake during PET/CT of the proximal colon (4 invasive cancers, 3 advanced adenomas and 4 false‑positive results), and 61 patients had no uptake in the proximal colon. Among these 61 patients, postoperative TCS revealed 2 invasive cancers and 4 advanced adenomas. The sensitivity of PET/CT for detecting synchronous invasive cancers was 66.6% (4/6), with a specificity of 89.4% (59/66), a positive predictive value of 36.4% (4/11), a negative predictive value of 96.7% (59/61), and an accuracy of 87.5% (63/72). Negative PET/CT results indicated a low probability of synchronous lesions in the proximal colon. Thus, PET/CT may be a useful tool for detecting synchronous colonic cancers in patients with obstructive colon cancer.
View Figures
View References

Related Articles

Journal Cover

April-2019
Volume 10 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Maeda C, Endo S, Mori Y, Mukai S, Hidaka E, Ishida F and Kudo S: The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Mol Clin Oncol 10: 425-429, 2019
APA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., & Kudo, S. (2019). The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Molecular and Clinical Oncology, 10, 425-429. https://doi.org/10.3892/mco.2019.1815
MLA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10.4 (2019): 425-429.
Chicago
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10, no. 4 (2019): 425-429. https://doi.org/10.3892/mco.2019.1815