Cutaneous and breast metastasis from colorectal adenocarcinoma: A rare case report

Liao,Xiu‑Yong; Liu,Chao‑Yuan; Liang,Li‑Bing; Du,Jiang‑Rong; Zhang,Tao

doi:10.3892/mco.2019.1866

Cutaneous and breast metastasis from colorectal adenocarcinoma: A rare case report

Authors:
- Xiu‑Yong Liao
- Chao‑Yuan Liu
- Li‑Bing Liang
- Jiang‑Rong Du
- Tao Zhang
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Affiliations: Department of Oncology, Chongqing Qiangjiang Central Hospital, Chongqing 409000, P.R. China, Department of Neurosurgery, Chongqing Qiangjiang Central Hospital, Chongqing 409000, P.R. China, Department of Pathology, Chongqing Qiangjiang Central Hospital, Chongqing 409000, P.R. China, Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China
Published online on: May 24, 2019 https://doi.org/10.3892/mco.2019.1866
Pages: 143-146

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Abstract

Synchronous breast and cutaneous metastases from colorectal adenocarcinoma as the initial clinical manifestation, without visceral metastases, are extremely rare. We herein report the case of a 68‑year‑old female patient who presented with pruritic skin lesions and a breast lump 6 years after abdominoperineal resection of colorectal adenocarcinoma. Such cases can be easily misdiagnosed as cutaneous metastasis from breast cancer. However, the management of colorectal metastases differs from that of primary breast cancer, and mastectomy may be unnecessary. Timely and accurate diagnosis requires a high level of suspicion, thorough medical clinical history and biopsy followed by immunohistological examination. Specific immunohistochemical markers, such as cytokeratin (CK)7, CK20 and CDX2, may help differentiate between primary breast and metastatic colorectal adenocarcinoma.

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