Rare presentation of small bowel adenocarcinoma with neuroendocrine differentiation in the jejunum: A case report and summary of diagnostic and management options

Cimpeanu,Emanuela; Zafar,Wahib; Circiumaru,Ioana; Prozumenshikov,Ariel; Salman,Shamim

doi:10.3892/mco.2019.1925

Rare presentation of small bowel adenocarcinoma with neuroendocrine differentiation in the jejunum: A case report and summary of diagnostic and management options

Authors:
- Emanuela Cimpeanu
- Wahib Zafar
- Ioana Circiumaru
- Ariel Prozumenshikov
- Shamim Salman
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Affiliations: Department of Internal Medicine, Richmond University Medical Center, Staten Island, NY 10310, USA, Department of Hematology and Medical Oncology, Westchester Medical Center, Valhalla, NY 10595, USA, Ross University School of Medicine, Miramar, FL 33027, USA, Department of Hematology and Medical Oncology, Richmond University Medical Center, Staten Island, NY 10310, USA
Published online on: September 23, 2019 https://doi.org/10.3892/mco.2019.1925
Pages: 461-464
Copyright: © Cimpeanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer of the small bowel (SB) is rare. The most common SB malignancy is neuroendocrine, followed by adenocarcinoma. SB adenocarcinoma with overlapping neuroendocrine differentiation (NED) is very uncommon. The present case report discusses the case of a young African American female who presented with high‑grade SB perforation and underwent urgent surgical repair. Histology of the tumor revealed jejunal adenocarcinoma with NED. To the best of our knowledge, this type of tumor has not yet been reported in the jejunum. Referring patients that present with insidious and nonspecific abdominal discomfort for imaging studies that are more sensitive to the SB could potentially identify tumors earlier, prevent the development of emergent gastrointestinal complications and offer a chance for cure. An overview of diagnostic tools for SB evaluation was provided.

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