Multiple recurrent follicular dendritic cell sarcoma: A case report

Schorn,Lara; Lommen,Julian; Depprich,Rita; Kübler,Norbert; Rana,Majeed; Heydt,Carina; Lohneis,Philipp; Kaiser,Peter; Sproll,Christoph

doi:10.3892/mco.2020.2093

Multiple recurrent follicular dendritic cell sarcoma: A case report

Authors:
- Lara Schorn
- Julian Lommen
- Rita Depprich
- Norbert Kübler
- Majeed Rana
- Carina Heydt
- Philipp Lohneis
- Peter Kaiser
- Christoph Sproll
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Affiliations: Department of Oral and Maxillofacial Surgery, Medical Faculty, Heinrich‑Heine‑University and University Hospital Düsseldorf, D-40225 Düsseldorf, Germany, Department of Pathology, Medical Faculty, University Hospital Cologne, D-50937 Cologne, Germany, Department of Pathology, Medical Faculty, Heinrich‑Heine‑University and University Hospital Düsseldorf, D-40225 Düsseldorf, Germany
Published online on: July 16, 2020 https://doi.org/10.3892/mco.2020.2093
Article Number: 23
Copyright: © Schorn et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Tumors of the follicular dendritic cells (FDC‑Sarcoma) represent a rare entity with only about 200 cases reported worldwide. The majority (60%) of cases arise primarily in cervical, abdominal or axillar lymph nodes, but extra nodal origin from secondary lymphatic tissue like the tonsils, Waldeyer's ring or MALT is also common (40%). The current report presents a characteristic course of a cervical FDC‑Sarcoma, with its challenges in establishing the initial diagnosis and the struggle for therapeutic options. The FDC‑Sarcoma presented recurrently for four times. Three different university hospitals in Germany were involved in the patients' treatment. Due to the patients' refusal, no adjuvant therapy was applied. In the end, a neck dissection was performed. The patient was closely followed up and has been recurrence‑free for 10 years. This case suggests operative resection in combination with a neck dissection as a curative therapy for FDC‑Sarcoma of the head and neck.

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