Long non‑coding RNAs in prostate tumorigenesis and therapy (Review)

  • Authors:
    • Ganggang Jiang
    • Zhengming Su
    • Xue Liang
    • Yiqiao Huang
    • Ziquan Lan
    • Xianhan Jiang
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  • Published online on: September 24, 2020     https://doi.org/10.3892/mco.2020.2146
  • Article Number: 76
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Abstract

Prostate cancer (PCa) is one of the most frequently diagnosed malignancy. Although there have been many advances in PCa diagnosis and therapy, the concrete mechanism remains unknown. Long non‑coding RNAs (lncRNAs) are novel biomarkers associated with PCa, and their dysregulated expression is closely associated with risk stratification, diagnosis and carcinogenesis. Accumulating evidence has suggested that lncRNAs play important roles in prostate tumorigenesis through relevant pathways, such as androgen receptor interaction and PI3K/Akt. The present review systematically summarized the potential clinical utility of lncRNAs and provided a novel guide for their function in PCa.
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December-2020
Volume 13 Issue 6

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
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Spandidos Publications style
Jiang G, Su Z, Liang X, Huang Y, Lan Z and Jiang X: Long non‑coding RNAs in prostate tumorigenesis and therapy (Review). Mol Clin Oncol 13: 76, 2020.
APA
Jiang, G., Su, Z., Liang, X., Huang, Y., Lan, Z., & Jiang, X. (2020). Long non‑coding RNAs in prostate tumorigenesis and therapy (Review). Molecular and Clinical Oncology, 13, 76. https://doi.org/10.3892/mco.2020.2146
MLA
Jiang, G., Su, Z., Liang, X., Huang, Y., Lan, Z., Jiang, X."Long non‑coding RNAs in prostate tumorigenesis and therapy (Review)". Molecular and Clinical Oncology 13.6 (2020): 76.
Chicago
Jiang, G., Su, Z., Liang, X., Huang, Y., Lan, Z., Jiang, X."Long non‑coding RNAs in prostate tumorigenesis and therapy (Review)". Molecular and Clinical Oncology 13, no. 6 (2020): 76. https://doi.org/10.3892/mco.2020.2146