Visceral plexiform schwannoma: A case series

Destro,Francesca; Sharma,Shilpa; Maestri,Luciano; Vella,Claudio; Collini,Paola; Riccipetitoni,Giovanna

doi:10.3892/mco.2020.2176

Visceral plexiform schwannoma: A case series

Authors:
- Francesca Destro
- Shilpa Sharma
- Luciano Maestri
- Claudio Vella
- Paola Collini
- Giovanna Riccipetitoni
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Affiliations: Department of Paediatric Surgery, Buzzi Children's Hospital, I‑20154 Milan, Italy, Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi 110029, India, Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, I‑20133 Milan, Italy
Published online on: November 26, 2020 https://doi.org/10.3892/mco.2020.2176
Article Number: 14

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Abstract

Plexiform schwannoma (PS) is a benign tumour of the peripheral nerve sheath that is typically found in the skin. Fewer than 15 cases of visceral PS have been reported to date in both adults and children. We herein discuss a series of 3 patients (2 male and 1 female) with abdominal PS, aged 10‑16 years (mean age, 12 years). All the patients had an acute presentation with abdominal pain, which was associated with rectal bleeding in 1 case and with walking difficulties in 1 case. Radiological investigations included abdominal magnetic resonance imaging (MRI) and computed tomography, along with neurofibromatosis screening (cerebral MRI and dermatological evaluation). Complete removal of the mass was possible in 2 of the patients (in 1 case by laparoscopically assisted surgery). Follow‑up was uneventful. Abdominal PS is a rare occurrence. Due to its possible association with neurofibromatosis, the diagnosis of PS should prompt an investigation for other manifestations of this disorder.

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