Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report

Mizuta,Haruki; Namikawa,Kenjiro; Nakama,Kenta; Yamazaki,Naoya

doi:10.3892/mco.2021.2209

Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report

Authors:
- Haruki Mizuta
- Kenjiro Namikawa
- Kenta Nakama
- Naoya Yamazaki
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Affiliations: Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo 104‑0045, Japan
Published online on: January 14, 2021 https://doi.org/10.3892/mco.2021.2209
Article Number: 47
Copyright: © Mizuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Spinal cord metastasis of malignant melanoma is mostly caused by the invasion of the spinal cord by malignant melanoma. However, direct metastasis in the spinal cord is rare and difficult to diagnose accurately. A few diagnostically valuable findings of intramedullary spinal cord metastases (ISCMs) have been published. However, a highly specific finding of ISCMs of all carcinomas is the ‘rim sign’, which signifies the enhancement of the edge‑dominant effect of the lesion in contrast‑enhanced MRI. The objective of this case series was to examine the ratio of ISCMs of malignant melanoma with an indication of rim signs in contrast‑enhanced MRI. The present report describes two cases of ISCMs of malignant melanoma in which the rim sign in contrast‑enhanced MRI was useful for diagnosis.

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