Electrochemotherapy in Kaposi sarcoma: A systematic review

  • Authors:
    • Martina Ferioli
    • Andrea Galuppi
    • Milly Buwenge
    • Silvia Cammelli
    • Anna  Myriam Perrone
    • Gabriella Macchia
    • Francesco Deodato
    • Savino  Cilla
    • Alice Zamagni
    • Francesca De Terlizzi
    • Luca Tagliaferri
    • Pierandrea De Iaco
    • Alessio Giuseppe Morganti
  • View Affiliations

  • Published online on: February 8, 2021     https://doi.org/10.3892/mco.2021.2226
  • Article Number: 64
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Abstract

Kaposi sarcoma (KS) is a rare angioproliferative disorder, which is usually associated with human herpesvirus‑8 infection. Electrochemotherapy (ECT) may be an option in the treatment of KS skin lesions due to the high response rate noted in neoplastic lesions of different histological types. The aim of the present systematic review was to analyse the available evidence on using ECT in the treatment of KS skin lesions. Tumor response, local control and toxicity were analyzed. In the three included studies, the complete response rate was 65‑100% and the overall response rate in all studies was 100%. The treatment was well tolerated with mild and transient toxicity. However, further studies are required to fully analyze long‑term disease control and to compare ECT with other local therapies used for KS.
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April-2021
Volume 14 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Ferioli M, Galuppi A, Buwenge M, Cammelli S, Perrone AM, Macchia G, Deodato F, Cilla S, Zamagni A, De Terlizzi F, De Terlizzi F, et al: Electrochemotherapy in Kaposi sarcoma: A systematic review. Mol Clin Oncol 14: 64, 2021.
APA
Ferioli, M., Galuppi, A., Buwenge, M., Cammelli, S., Perrone, A.M., Macchia, G. ... Morganti, A.G. (2021). Electrochemotherapy in Kaposi sarcoma: A systematic review. Molecular and Clinical Oncology, 14, 64. https://doi.org/10.3892/mco.2021.2226
MLA
Ferioli, M., Galuppi, A., Buwenge, M., Cammelli, S., Perrone, A. M., Macchia, G., Deodato, F., Cilla, S., Zamagni, A., De Terlizzi, F., Tagliaferri, L., De Iaco, P., Morganti, A. G."Electrochemotherapy in Kaposi sarcoma: A systematic review". Molecular and Clinical Oncology 14.4 (2021): 64.
Chicago
Ferioli, M., Galuppi, A., Buwenge, M., Cammelli, S., Perrone, A. M., Macchia, G., Deodato, F., Cilla, S., Zamagni, A., De Terlizzi, F., Tagliaferri, L., De Iaco, P., Morganti, A. G."Electrochemotherapy in Kaposi sarcoma: A systematic review". Molecular and Clinical Oncology 14, no. 4 (2021): 64. https://doi.org/10.3892/mco.2021.2226