Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region

Vinh,Quang Bui; Quoc,Soai Dang; Van,Toan Hoang; Vu,Truong; Thi,Tuyet Pham

doi:10.3892/mco.2023.2639

Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region

Authors:
- Quang Bui Vinh
- Soai Dang Quoc
- Toan Hoang Van
- Truong Vu
- Tuyet Pham Thi
View Affiliations

Affiliations: Radiotherapy Department, Hanoi Oncology Hospital, Hai Ba Trung, Hanoi 100000, Vietnam, Medical Physics Division, Hanoi Oncology Hospital, Hai Ba Trung, Hanoi 100000, Vietnam
Published online on: March 30, 2023 https://doi.org/10.3892/mco.2023.2639
Article Number: 43
Copyright: © Vinh et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity‑modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient.

View Figures

View References

1	Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68:394–424. 2018.PubMed/NCBI View Article : Google Scholar
2	Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021.PubMed/NCBI View Article : Google Scholar
3	Bostock S and Bryan J: Radiotherapy-induced skin reactions: Assessment and management. Br J Nurs. 25(S18, S20-4)2016.PubMed/NCBI View Article : Google Scholar
4	Anscher MS: Radiation Toxicity-A Practical Guide. Int J Radiat Oncol Biol Phys. 70(1611)2008.
5	Archambeau JO, Pezner R and Wasserman T: Pathophysiology of irradiated skin and breast. Int J Radiat Oncol Biol Phys. 31:1171–1185. 1995.PubMed/NCBI View Article : Google Scholar
6	Varian Medical Systems. Inc: Eclipse Algorithms Reference Guide. Palo Alto, CA, 2009.
7	Lee NY, Riaz N and Lu JJ: Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy. Springer International Publishing, Cham, 2015.
8	International Commission on Radiation Units and Measurements: Prescribing, recording, and reporting photon beam therapy. Internat. Comm. on Radiation Units and Measurements, Bethesda, MD, 1993.
9	Li H, Dong L, Zhang L, Yang JN, Gillin MT and Zhu XR: Toward a better understanding of the gamma index: Investigation of parameters with a surface-based distance method. Med Phys. 38:6730–6741. 2011.PubMed/NCBI View Article : Google Scholar
10	Kataria T, Sharma K, Subramani V, Karrthick KP and Bisht S: Homogeneity Index: An objective tool for assessment of conformal radiation treatments. J Med Phys. 37:207–213. 2012.PubMed/NCBI View Article : Google Scholar
11	Cox JD, Stetz J and Pajak TF: Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European organization for research and treatment of cancer (EORTC). Int J Radiat Oncol Biol Phys. 31:1341–1346. 1995.PubMed/NCBI View Article : Google Scholar
12	Hollinworth H and Mann L: Managing acute skin reactions to radiotherapy treatment. Nurs Stand. 24:53–54, 56, 58 passim. 2010.PubMed/NCBI View Article : Google Scholar
13	Pires AM, Segreto RA and Segreto HR: RTOG criteria to evaluate acute skin reaction and its risk factors in patients with breast cancer submitted to radiotherapy. Rev Lat Am Enfermagem. 16:844–849. 2008.PubMed/NCBI View Article : Google Scholar
14	Lavery BA: Skin care during radiotherapy: A survey of UK practice. Clin Oncol (R Coll Radiol). 7:184–187. 1995.PubMed/NCBI View Article : Google Scholar
15	McQuestion M: Evidence-Based skin care management in radiation therapy. Semin Oncol Nurs. 22:163–173. 2006.PubMed/NCBI View Article : Google Scholar
16	Schratter-Sehn AU, Brinda K, Kahrer M and Novak M: Improvement of skin care during radiotherapy. Onkologie. 24:44–46. 2001.PubMed/NCBI View Article : Google Scholar
17	Salvo N, Barnes E, van Draanen J, Stacey E, Mitera G, Breen D, Giotis A, Czarnota G, Pang J and De Angelis C: Prophylaxis and management of acute radiation-induced skin reactions: A systematic review of the literature. Curr Oncol. 17:94–112. 2010.PubMed/NCBI View Article : Google Scholar
18	Wei J, Meng L, Hou X, Qu C, Wang B, Xin Y and Jiang X: Radiation-induced skin reactions: Mechanism and treatment. Cancer Manag Res. 11:167–177. 2018.PubMed/NCBI View Article : Google Scholar
19	D'Haese S, Bate T, Claes S, Boone A, Vanvoorden V and Efficace F: Management of skin reactions during radiotherapy: A study of nursing practice. Eur J Cancer Care (Engl). 14:28–42. 2005.PubMed/NCBI View Article : Google Scholar
20	Harper JL, Franklin LE, Jenrette JM and Aguero EG: Skin toxicity during breast irradiation: Pathophysiology and management. South Med J. 97:989–993. 2004.PubMed/NCBI View Article : Google Scholar
21	Hymes SR, Strom EA and Fife C: Radiation dermatitis: Clinical presentation, pathophysiology, and treatment 2006. J Am Acad Dermatol. 54:28–46. 2006.PubMed/NCBI View Article : Google Scholar
22	Roy I, Fortin A and Larochelle M: The impact of skin washing with water and soap during breast irradiation: A randomized study. Radiother Oncol. 58:333–339. 2001.PubMed/NCBI View Article : Google Scholar
23	Schreck U, Paulsen F, Bamberg M and Budach W: Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme Or Powder? Strahlenther Onkol. 178:321–329. 2002.PubMed/NCBI View Article : Google Scholar