Open Access

Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review

  • Authors:
    • Meiqing Wu
    • Zhongqing Li
    • Lin Luo
    • Weihua Zhao
    • Jun Luo
  • View Affiliations

  • Published online on: January 4, 2024     https://doi.org/10.3892/mco.2024.2714
  • Article Number: 16
  • Copyright: © Wu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Angiosarcomas, originating from endothelial cells, are infrequent soft tissue sarcomas characterized by a high propensity for metastasis and an unfavorable prognosis. Splenic angiosarcoma, an exceedingly rare and aggressive neoplasm, exhibits variable clinical manifestations. The present case report describes a patient initially exhibiting anemia and bone marrow fibrosis, mimicking primary myelofibrosis, ultimately diagnosed with splenic angiosarcoma. The findings of the present case report underscore the importance of considering splenectomy for histopathological confirmation. Employing a panel of vascular differentiation markers is invaluable for establishing the diagnosis of angiosarcoma.
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February-2024
Volume 20 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Wu M, Li Z, Luo L, Zhao W and Luo J: Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review. Mol Clin Oncol 20: 16, 2024.
APA
Wu, M., Li, Z., Luo, L., Zhao, W., & Luo, J. (2024). Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review. Molecular and Clinical Oncology, 20, 16. https://doi.org/10.3892/mco.2024.2714
MLA
Wu, M., Li, Z., Luo, L., Zhao, W., Luo, J."Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review". Molecular and Clinical Oncology 20.2 (2024): 16.
Chicago
Wu, M., Li, Z., Luo, L., Zhao, W., Luo, J."Metastatic splenic angiosarcoma presenting with anemia and bone marrow fibrosis mimicking primary myelofibrosis: A case report and literature review". Molecular and Clinical Oncology 20, no. 2 (2024): 16. https://doi.org/10.3892/mco.2024.2714