Solitary large malignant lymphoma in the head and neck region
- Authors:
- Dae-Neung Lee
- Dong Hoon Lee
- Joo Yeon Koo
- Sang Chul Lim
View Affiliations
Affiliations: Department of Otolaryngology‑Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Jeonnam 58128, Republic of Korea, Department of Pathology, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Jeonnam 58128, Republic of Korea
- Published online on: April 17, 2024 https://doi.org/10.3892/mco.2024.2737
-
Article Number:
39
-
Copyright: © Lee
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License.
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Abstract
The present study examined the clinical characteristics of patients with a final diagnosis of solitary large malignant lymphoma of the head and neck after surgery. Between January 2015 and December 2022, 13 patients with a final diagnosis of solitary large malignant lymphoma of the head and neck after surgery were enrolled. The most common symptom of solitary large malignant lymphoma was a neck mass (n=11; 84.6%). The most common sites of the head and neck were neck level II (eight patients), neck level IV (two patients), parotid glands (two patients) and the tongue (two patients). The number of malignant lymphomas was as follows: 11 patients had one large tumor and two patients had two large tumors. The mean tumor size was 4.0±1.3 cm (range; 2.7‑6.8 cm). Among the two patients with two lymphomas, the size of the second neck mass was 3.2 cm in one patient and 2.7 cm in the other patient. The most common type of solitary large malignant lymphoma was diffuse large B‑cell lymphoma (n=6, 46.2%). A total of 12 patients are currently under follow‑up without disease recurrence after treatment completion and one patient diagnosed 1 month ago is currently undergoing radiation therapy. The follow‑up period was 47.3±19.0 months (range; 1‑62 months). The possibility of solitary large malignant lymphoma of the head and neck should be considered. As it is difficult to accurately diagnose solitary large malignant lymphoma before surgery, surgical resection is required for differentiation from other diseases.
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