Clinical characteristics and surgical strategy of sporadic cerebellar hemangioblastomas

Hao,Guangzhi; Zhang,Bingying; Li,Yuanyuan; Wu,Yue; Han,Yuwei; Chen,Xiang

doi:10.3892/mco.2024.2781

Clinical characteristics and surgical strategy of sporadic cerebellar hemangioblastomas

Authors:
- Guangzhi Hao
- Bingying Zhang
- Yuanyuan Li
- Yue Wu
- Yuwei Han
- Xiang Chen
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Affiliations: Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China, Second Stationed Out‑Patient Department, General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, P.R. China
Published online on: September 9, 2024 https://doi.org/10.3892/mco.2024.2781
Article Number: 83
Copyright: © Hao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Hemangioblastoma is a rare benign vascular tumor that occurs mostly in the cerebellum. The aim of the present study was to analyze the clinical characteristics of sporadic cerebellar hemangioblastoma and its surgical strategy. A total of 76 cases of sporadic cerebellar hemangioblastoma (42 males and 34 females; age, 46.4±13.9 years; age range, 23‑72 years) admitted to the Department of Neurosurgery of the General Hospital of Northern Theater Command (Shenyang, China) from July 2012 to April 2021 were retrospectively analyzed. All patients had only one isolated tumor and underwent surgical resection. Their basic characteristics, serial radiographic examinations, surgical records and follow‑up were analyzed. A total of 57 patients with cystic hemangioblastoma and eight patients with cystic solid hemangioblastoma directly underwent resection treatment. Of 11 patients with solid hemangioblastoma, 8 underwent vascular embolization prior to surgical resection. Furthermore, 3 patients with solid hemangioblastoma who were not embolized prior to surgery had intraoperative hemorrhage and poor prognosis. In addition, 3 patients underwent partial resection of the tumor and all of them suffered recurrence after the surgery. A total of 71 patients achieved good neurologic improvement. However, 5 patients had a poor prognosis after the initial surgery. In conclusion, total microsurgical resection is essential to improve the health status of patients with sporadic cerebellar cystic hemangioblastoma. In addition, preoperative embolization of arteries supplying solid hemangioblastomas can reduce intraoperative bleeding and improve prognosis.

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