Open Access

Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature

  • Authors:
    • Abdulwahid M. Salih
    • Aras J. Qaradakhy
    • Shko H. Hassan
    • Ari M. Abdullah
    • Hardi Mohammed Dhahir
    • Sanaa O. Karim
    • Hawar A. Sofi
    • Berun A. Abdalla
    • Muhammad Hassan Ali
    • Fahmi H. Kakamad
  • View Affiliations

  • Published online on: September 5, 2023     https://doi.org/10.3892/mi.2023.109
  • Article Number: 49
  • Copyright : © Salih et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Tuberculosis of the thyroid gland is rare, and tuberculous granulomatous inflammation of the parathyroid glands is even rarer. The present study reports a rare case of primary hyperparathyroidism caused by tuberculous granulomatous inflammation. A 58‑year‑old female patient presented with generalized body pain persisting for 1 year. She had a history of recurrent renal stones (>20 times) and an incidental finding of multinodular goiter involving the parathyroid on neck ultrasound. A blood analysis revealed elevated levels of serum calcium (11.26 mg/dl) and parathyroid hormone (154.7 pg/ml). The patient underwent the resection of the affected left thyroid lobe under general anesthesia. A histopathological examination revealed parathyroid adenoma with caseating granulomatous inflammation involving the adenoma with focal lymphocytic thyroiditis of the left thyroid gland. Although granulomatous parathyroid disease with parathyroid adenoma causing hypercalcemia is an extremely rare event, it can occur. The treatment of choice is surgical resection.
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September-October 2023
Volume 3 Issue 5

Print ISSN: 2754-3242
Online ISSN:2754-1304

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Spandidos Publications style
Salih AM, Qaradakhy AJ, Hassan SH, Abdullah AM, Dhahir HM, Karim SO, Sofi HA, Abdalla BA, Ali MH, Kakamad FH, Kakamad FH, et al: Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature. Med Int 3: 49, 2023.
APA
Salih, A.M., Qaradakhy, A.J., Hassan, S.H., Abdullah, A.M., Dhahir, H.M., Karim, S.O. ... Kakamad, F.H. (2023). Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature. Medicine International, 3, 49. https://doi.org/10.3892/mi.2023.109
MLA
Salih, A. M., Qaradakhy, A. J., Hassan, S. H., Abdullah, A. M., Dhahir, H. M., Karim, S. O., Sofi, H. A., Abdalla, B. A., Ali, M. H., Kakamad, F. H."Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature". Medicine International 3.5 (2023): 49.
Chicago
Salih, A. M., Qaradakhy, A. J., Hassan, S. H., Abdullah, A. M., Dhahir, H. M., Karim, S. O., Sofi, H. A., Abdalla, B. A., Ali, M. H., Kakamad, F. H."Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature". Medicine International 3, no. 5 (2023): 49. https://doi.org/10.3892/mi.2023.109