Efficacy of ultrasound‑guided platelet rich plasma injection for the management of de Quervain's tenosynovitis

Asaad,Saywan K.; Mahmood,Kawa A.; Arif,Sakar O.; Abdalla,Berun A.; Salih,Abdulwahid M.; Kakamad,Fahmi H.; Mohammed,Shvan H.; Salih,Rawezh Q.; Mohammed,Karukh K.; Salih,Karzan M.

doi:10.3892/mi.2023.72

Efficacy of ultrasound‑guided platelet rich plasma injection for the management of de Quervain's tenosynovitis

Authors:
- Saywan K. Asaad
- Kawa A. Mahmood
- Sakar O. Arif
- Berun A. Abdalla
- Abdulwahid M. Salih
- Fahmi H. Kakamad
- Shvan H. Mohammed
- Rawezh Q. Salih
- Karukh K. Mohammed
- Karzan M. Salih
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Affiliations: Department of Surgery, College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46000, Iraq, Department of Radiology, Shar Hospital, Sulaimani, Kurdistan 46000, Iraq, Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq, Kscien Organization, Sulaimani, Kurdistan 46000, Iraq
Published online on: February 2, 2023 https://doi.org/10.3892/mi.2023.72
Article Number: 12
Copyright: © Asaad et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

De Quervain's tenosynovitis (DQT) is a painful stenosing tenosynovitis of the first dorsal compartment of the wrist, which may be refractory to conservative treatments. The present study aimed to evaluate the efficacy of ultrasound (US)‑guided platelet‑rich plasma (PRP) injection for the management of DQT. For this purpose, from January, 2020 to February, 2021, 12 patients with DQT who received the US‑guided PRP injection were studied prospectively. All patients were evaluated clinically for pain intensity using the visual analog scale and sonographically prior to treatment. The patients were followed‑up at 1 and 3 months after the procedure to evaluate the efficacy of the treatment. In total, 12 hands of 12 female patients with DQT were analyzed in the present study. The post‑treatment clinical evaluation revealed complete recovery in 4 (33.3%) of the patients, and 6 (50%) of them had recovered and returned to their daily activities. The sonographic evaluation revealed a significant reduction in the mean retinaculum thickness from 1.84 to 1.069 mm, and mean tendon sheath effusion from 2.06 to 1.25 mm, with only 58% of the cases having tendon sheath effusion at 3 months post‑treatment. On the whole, the findings of the present study demonstrate that US‑guided PRP injection with needle tenotomy can be used as an alternative non‑surgical therapy for patients who do not respond to conventional conservative treatments, particularly in cases with sub‑compartmentalization. The use of US may play a crucial role in the treatment of DQT, as improved clinical outcomes can be obtained with US‑guided injections, particularly in cases with sub‑compartmentalization.

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