Open Access

Evaluation and establishment of a canine model of delayed splenic rupture using contrast-enhanced ultrasound

  • Authors:
    • Jiangke Tian
    • Xia Xie
    • Faqin Lv
    • Tengfei Yu
    • Rong Wu
    • Xinghua Zhang
    • Dong Wang
    • Jie Tang
  • View Affiliations

  • Published online on: June 14, 2012     https://doi.org/10.3892/mmr.2012.948
  • Pages: 483-487
  • Copyright: © Tian et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 3.0].

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Abstract

The aim of the present study was to establish a canine model of delayed splenic rupture (DSR). A total of 15 mongrel dogs were anesthetized and laparotomized. The hematomas were observed following an injection of heparin. The hematomas were ruptured. The severity of the spleen rupture was evaluated and the intra-abdominal free liquid was measured. The splenic hematomas in the dogs continued to form and the hematoma area gradually increased. The hematomas were ruptured after impacting the abdominal wall. The spleens were damaged, and conventional ultrasonography showed intra-abdominal free liquid. These conditions were demonstrated via computed tomography scanning. A DSR canine model was established successfully.
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September 2012
Volume 6 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Tian J, Xie X, Lv F, Yu T, Wu R, Zhang X, Wang D and Tang J: Evaluation and establishment of a canine model of delayed splenic rupture using contrast-enhanced ultrasound. Mol Med Rep 6: 483-487, 2012.
APA
Tian, J., Xie, X., Lv, F., Yu, T., Wu, R., Zhang, X. ... Tang, J. (2012). Evaluation and establishment of a canine model of delayed splenic rupture using contrast-enhanced ultrasound. Molecular Medicine Reports, 6, 483-487. https://doi.org/10.3892/mmr.2012.948
MLA
Tian, J., Xie, X., Lv, F., Yu, T., Wu, R., Zhang, X., Wang, D., Tang, J."Evaluation and establishment of a canine model of delayed splenic rupture using contrast-enhanced ultrasound". Molecular Medicine Reports 6.3 (2012): 483-487.
Chicago
Tian, J., Xie, X., Lv, F., Yu, T., Wu, R., Zhang, X., Wang, D., Tang, J."Evaluation and establishment of a canine model of delayed splenic rupture using contrast-enhanced ultrasound". Molecular Medicine Reports 6, no. 3 (2012): 483-487. https://doi.org/10.3892/mmr.2012.948