Pharmacology and phytochemistry of the Nitraria genus (Review)

Du,Qiaohui; Xin,Hailiang; Peng,Cheng

doi:10.3892/mmr.2014.2677

Pharmacology and phytochemistry of the Nitraria genus (Review)

Authors:
- Qiaohui Du
- Hailiang Xin
- Cheng Peng
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Affiliations: Key Laboratory of Standardization of Chinese Herbal Medicines of the Ministry of Education, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, P.R. China, Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China
Published online on: October 16, 2014 https://doi.org/10.3892/mmr.2014.2677
Pages: 11-20

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Abstract

Plants from the Nitraria genus, members of the Zygophyllaceae family, grow naturally in Europe, Africa, Australia and the central Asian desert. Previous pharmacological research has provided evidence that members of the Nitraria genus have numerous beneficial effects. In the present review, the pharmacological and phytochemical studies of Nitraria were presented and assessed. The review was written using information published between 1968 and 2013 from a number of reliable sources, including ScienceDirect, Springer, PubMed, EMBASE and CNKI. Numerous compounds, such as alkaloids and flavonoids have been isolated from the plants of this genus in the past, and multiple members of these constituents have been demonstrated to exert antitumor or anti‑oxidative activities. The extracts of plants of the Nitraria genus possess antitumor, antiproliferative, anti‑oxidative, antifatigue, anti‑mutagenic, antimicrobial, hypotensive, hepatoprotective, lipid‑lowering and hypoglycemic effects. However, the possible active components in the fraction and the molecular mechanisms require further investigation prior to their use in clinical practice.

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