1
|
Kondo T, Ezzat S and Asa SL: Pathogenetic
mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer.
6:292–306. 2006. View
Article : Google Scholar : PubMed/NCBI
|
2
|
Xing M: Molecular pathogenesis and
mechanisms of thyroid cancer. Nat Rev Cancer. 13:184–199. 2013.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Nikiforov YE and Nikiforova MN: Molecular
genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol.
7:569–580. 2011. View Article : Google Scholar : PubMed/NCBI
|
4
|
Rossner MJ, Oster H, Wichert SP, Reinecke
L, Wehr MC, Reinecke J, Eichele G, Taneja R and Nave KA: Disturbed
clockwork resetting in Sharp-1 and Sharp-2 single and double mutant
mice. PloS One. 3:e27622008. View Article : Google Scholar : PubMed/NCBI
|
5
|
Yamada K and Miyamoto K: Basic
helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their
gene expressions are regulated by multiple extracellular stimuli.
Front Biosci. 10:3151–3171. 2005. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Sun H, Ghaffari S and Taneja R:
bHLH-Orange transcription factors in development and cancer. Transl
Oncogenomics. 2:107–120. 2007.PubMed/NCBI
|
7
|
Azmi S, Sun H, Ozog A and Taneja R:
mSharp-1/DEC2, a basic helix-loop-helix protein functions as a
transcriptional repressor of E box activity and Stra13 expression.
J Biol Chem. 278:20098–20109. 2003. View Article : Google Scholar : PubMed/NCBI
|
8
|
Fujimoto K, Shen M, Noshiro M, Matsubara
K, Shingu S, Honda K, Yoshida E, Suardita K, Matsuda Y and Kato Y:
Molecular cloning and characterization of DEC2, a new member of
basic helix-loop-helix proteins. Biochem Biophys Res Commun.
280:164–171. 2001. View Article : Google Scholar : PubMed/NCBI
|
9
|
Muller PA, Vousden KH and Norman JC: p53
and its mutants in tumor cell migration and invasion. J Cell Biol.
192:209–218. 2011. View Article : Google Scholar : PubMed/NCBI
|
10
|
Sermeus A and Michiels C: Reciprocal
influence of the p53 and the hypoxic pathways. Cell Death Dis.
2:e1642011. View Article : Google Scholar : PubMed/NCBI
|
11
|
Montagner M, Enzo E, Forcato M, Zanconato
F, Parenti A, Rampazzo E, Basso G, Leo G, Rosato A, Bicciato S, et
al: SHARP1 suppresses breast cancer metastasis by promoting
degradation of hypoxia-inducible factors. Nature. 487:380–384.
2012. View Article : Google Scholar : PubMed/NCBI
|
12
|
Wu Y, Sato F, Bhawal UK, Kawamoto T,
Fujimoto K, Noshiro M, Seino H, Morohashi S, Kato Y and Kijima H:
BHLH transcription factor DEC2 regulates pro-apoptotic factor Bim
in human oral cancer HSC-3 cells. Biomed Res. 33:75–82. 2012.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Cui J, Mao X, Olman V, Hastings P and Xu
Y: Hypoxia and miscoupling between reduced energy efficiency and
signaling to cell proliferation drive cancer to grow increasingly
faster. J Mol Cell Biol. 4:174–176. 2012. View Article : Google Scholar : PubMed/NCBI
|
14
|
Solaini G, Baracca A, Lenaz G and Sgarbi
G: Hypoxia and mitochondrial oxidative metabolism. Biochim Biophys
Acta. 1797:1171–1177. 2010. View Article : Google Scholar : PubMed/NCBI
|
15
|
Bruick RK: Oxygen sensing in the hypoxic
response pathway: Regulation of the hypoxia-inducible transcription
factor. Genes Dev. 17:2614–2623. 2003. View Article : Google Scholar : PubMed/NCBI
|
16
|
Semenza GL: Targeting HIF-1 for cancer
therapy. Nat Rev Cancer. 3:721–732. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Liao Y, Lu W, Che Q, Yang T, Qiu H, Zhang
H, He X, Wang J, Qiu M, Zou Y, et al: SHARP1 suppresses
angiogenesis of endometrial cancer by decreasing hypoxia-inducible
factor-1α level. PloS One. 9:e999072014. View Article : Google Scholar
|
18
|
Li J, Xu Y, Jiao H, Wang W, Mei Z and Chen
G: Sumoylation of hypoxia inducible factor-1α and its significance
in cancer. Sci China Life Sci. 57:657–664. 2014. View Article : Google Scholar : PubMed/NCBI
|
19
|
Payton JE, Grieselhuber NR, Chang LW,
Murakami M, Geiss GK, Link DC, Nagarajan R, Watson MA and Ley TJ:
High throughput digital quantification of mRNA abundance in primary
human acute myeloid leukemia samples. J Clin Invest. 119:1714–1726.
2009. View
Article : Google Scholar : PubMed/NCBI
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real time quantitative PCR and
the 2(Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
21
|
Kawamoto T, Noshiro M, Furukawa M, Honda
KK, Nakashima A, Ueshima T, Usui E, Katsura Y, Fujimoto K, Honma S,
et al: Effects of fasting and re-feeding on the expression of Dec1,
Per1 and other clock-related genes. J Biochem. 140:401–408. 2006.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Rohleder N, Langer C, Maus C,
Spiwoks-Becker I, Emser A, Engel L and Spessert R: Influence of
photoperiodic history on clock genes and the circadian pacemaker in
the rat retina. Eur J Neurosci. 23:105–111. 2006. View Article : Google Scholar : PubMed/NCBI
|
23
|
Azmi S, Ozog A and Taneja R: Sharp-1/DEC2
inhibits skeletal muscle differentiation through repression of
myogenic transcription factors. J Biol Chem. 279:52643–52652. 2004.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Falvella F, Colombo F, Spinola M,
Campiglio M, Pastorino U and Dragani T: BHLHB3: A candidate tumor
suppressor in lung cancer. Oncogene. 27:3761–3764. 2008. View Article : Google Scholar : PubMed/NCBI
|
25
|
Wu Y, Sato F, Bhawal UK, Kawamoto T,
Fujimoto K, Noshiro M, Morohashi S, Kato Y and Kijima H: Basic
helix-loop-helix transcription factors DEC1 and DEC2 regulate the
paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer
cells. Int J Mol Med. 27:491–495. 2011.PubMed/NCBI
|
26
|
van't Veer LJ, Dai H, Van De Vijver MJ, He
YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, et al:
Gene expression profiling predicts clinical outcome of breast
cancer. Nature. 415:530–536. 2002. View
Article : Google Scholar
|
27
|
Bragado P, Estrada Y, Parikh F, Krause S,
Capobianco C, Farina HG, Schewe DM and Aguirre-Ghiso JA: TGF-β2
dictates disseminated tumour cell fate in target organs through
TGF-β-RIII and p38α/β signalling. Nat Cell Biol. 15:1351–1361.
2013. View
Article : Google Scholar : PubMed/NCBI
|
28
|
Foster JG, Wong SC and Sharp TV: The
hypoxic tumor micro-environment: Driving the tumorigenesis of
non-small-cell lung cancer. Future Oncol. 10:2659–2674. 2014.
View Article : Google Scholar
|
29
|
Bernardi R and Gianni L: Hallmarks of
triple negative breast cancer emerging at last? Cell Res.
24:904–905. 2014. View Article : Google Scholar : PubMed/NCBI
|
30
|
Burgess DJ: Tumour suppressors: At the
SHARP end of metastasis. Nat Rev Cancer. 12:580–581. 2012.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Sato F, Bhawal UK, Kawamoto T, et al:
Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively
regulates vascular endothelial growth factor expression. Genes
Cells. 13:131–144. 2008. View Article : Google Scholar : PubMed/NCBI
|
32
|
Shafee N, Kaluz S, Ru N and Stanbridge EJ:
PI3K/Akt activity has variable cell-specific effects on expression
of HIF target genes, CA9 and VEGF, in human cancer cell lines.
Cancer Lett. 282:109–115. 2009. View Article : Google Scholar : PubMed/NCBI
|
33
|
Méndez O, Zavadil J, Esencay M, et al:
Research Knock down of HIF-1alpha in glioma cells reduces migration
in vitro and invasion in vivo and impairs their ability to form
tumor spheres. Mol Cancer. 9:1332010. View Article : Google Scholar
|
34
|
Fujiwara S, Nakagawa K, Harada H, et al:
Silencing hypoxia-inducible factor-1alpha inhibits cell migration
and invasion under hypoxic environment in malignant gliomas. Int J
Oncol. 30:793–802. 2007.PubMed/NCBI
|
35
|
Krishnamachary B, Berg-Dixon S, Kelly B,
Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P
and Semenza GL: Regulation of colon carcinoma cell invasion by
hypoxia-inducible factor 1. Cancer Res. 63:1138–1143.
2003.PubMed/NCBI
|
36
|
Li Y, Qiu X, Zhang S, Zhang Q and Wang E:
Hypoxia-induced CCR7 expression via HIF-1alpha and HIF-2alpha
correlates with migration and invasion in lung cancer cells. Cancer
Biol Ther. 8:322–330. 2009. View Article : Google Scholar : PubMed/NCBI
|
37
|
Wang Y, Li Z, Zhang H, Jin H, Sun L, Dong
H, Xu M, Zhao P, Zhang B, Wang J, et al: HIF-1α and HIF-2α
correlate with migration and invasion in gastric cancer. Cancer
Biol Ther. 10:376–382. 2010. View Article : Google Scholar : PubMed/NCBI
|