1
|
Guiot J, Corhay JL and Louis R: Idiopathic
pulmonary fibrosis. Rev Med Liege. 69:605–610. 2014.PubMed/NCBI
|
2
|
Kim HJ, Perlman D and Tomic R: Natural
history of idiopathic pulmonary fibrosis. Respir Med. 109:661–670.
2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Gharaee-Kermani M, Gyetko MR, Hu B and
Phan SH: New insights into the pathogenesis and treatment of
idiopathic pulmonary fibrosis: A potential role for stem cells in
the lung parenchyma and implications for therapy. Pharm Res.
24:819–841. 2007. View Article : Google Scholar : PubMed/NCBI
|
4
|
Fernandez IE and Eickelberg O: New
cellular and molecular mechanisms of lung injury and fibrosis in
idiopathic pulmonary fibrosis. Lancet. 380:680–688. 2012.
View Article : Google Scholar : PubMed/NCBI
|
5
|
King TE Jr, Pardo A and Selman M:
Idiopathic pulmonary fibrosis. Lancet. 378:1949–1961. 2011.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Yan W, Xiaoli L, Guoliang A, Zhonghui Z,
Di L, Ximeng L, Piye N, Li C and Lin T: SB203580 inhibits
epithelial-mesenchymal transition and pulmonary fibrosis in a rat
silicosis model. Toxicol Lett. 259:28–34. 2016. View Article : Google Scholar : PubMed/NCBI
|
7
|
Harrison JH Jr and Lazo JS: High dose
continuous infusion of bleomycin in mice: A new model for
drug-induced pulmonary fibrosis. J Pharmacol Exp Ther.
243:1185–1194. 1987.PubMed/NCBI
|
8
|
Moeller A, Ask K, Warburton D, Gauldie J
and Kolb M: The bleomycin animal model: A useful tool to
investigate treatment options for idiopathic pulmonary fibrosis?
Int J Biochem Cell Biol. 40:362–382. 2008. View Article : Google Scholar : PubMed/NCBI
|
9
|
Adamson IY and Bowden DH: The pathogenesis
of bleomycin-induced pulmonary fibrosis in mice. Am J Pathol.
77:185–197. 1974.PubMed/NCBI
|
10
|
Moore BB and Hogaboam CM: Murine models of
pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol.
294:L152–L160. 2008. View Article : Google Scholar : PubMed/NCBI
|
11
|
Kim HS, Go H, Akira S and Chung DH:
TLR2-mediated production of IL-27 and chemokines by respiratory
epithelial cells promotes bleomycin-induced pulmonary fibrosis in
mice. J Immunol. 187:4007–4017. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
Degryse AL, Tanjore H, Xu XC, Polosukhin
VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB,
Gleaves LA, et al: TGFβ signaling in lung epithelium regulates
bleomycin-induced alveolar injury and fibroblast recruitment. Am J
Physiol Lung Cell Mol Physiol. 300:L887–L897. 2011. View Article : Google Scholar : PubMed/NCBI
|
13
|
Chen YL, Zhang X, Bai J, Gai L, Ye XL,
Zhang L, Xu Q, Zhang YX, Xu L, Li HP and Ding X: Sorafenib
ameliorates bleomycin-induced pulmonary fibrosis: Potential roles
in the inhibition of epithelial-mesenchymal transition and
fibroblast activation. Cell Death Dis. 4:e6652013. View Article : Google Scholar : PubMed/NCBI
|
14
|
Yin MM, Cui YR, Wang L, Wang JY, Gao Y and
Xi JY: Progress on PI3K/Akt signaling pathway regulating
self-renewal and pluripotency of embryonic stem cells. Sheng Li Xue
Bao. 66:223–230. 2014.(In Chinese). PubMed/NCBI
|
15
|
Diehl N and Schaal H: Make yourself at
home: Viral hijacking of the PI3K/Akt signaling pathway. Viruses.
5:3192–3212. 2013. View
Article : Google Scholar : PubMed/NCBI
|
16
|
Diab S, Fidanzi C, Léger DY, Ghezali L,
Millot M, Martin F, Azar R, Esseily F, Saab A, Sol V, et al:
Berberis libanotica extract targets NF-κB/COX-2, PI3K/Akt and
mitochondrial/caspase signalling to induce human erythroleukemia
cell apoptosis. Int J Oncol. 47:220–230. 2015.PubMed/NCBI
|
17
|
Ribback S, Cigliano A, Kroeger N, Pilo MG,
Terracciano L, Burchardt M, Bannasch P, Calvisi DF and Dombrowski
F: PI3K/AKT/mTOR pathway plays a major pathogenetic role in
glycogen accumulation and tumor development in renal distal tubules
of rats and men. Oncotarget. 30:13036–13048. 2015. View Article : Google Scholar
|
18
|
Xu X, Li H, Hou X, Li D, He S, Wan C, Yin
P, Liu M, Liu F and Xu J: Punicalagin induces Nrf2/HO-1 expression
via upregulation of PI3K/AKT pathway and inhibits LPS-induced
oxidative stress in RAW264.7 macrophages. Mediators Inflamm.
2015:3802182015. View Article : Google Scholar : PubMed/NCBI
|
19
|
Chen H, Mei YQ and Solomon MA: Experiences
of establishing an abdominal heart transplantation model in rats.
Zhonghua Yi Xue Za Zhi. 92:1715–1718. 2012.(In Chinese). PubMed/NCBI
|
20
|
Szapiel SV, Elson NA, Fulmer JD,
Hunninghake GW and Crystal RG: Bleomycin-induced interstitial
pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis.
120:893–899. 1979.PubMed/NCBI
|
21
|
Huang LS, Berdyshev E, Mathew B, Fu P,
Gorshkova IA, He D, Ma W, Noth I, Ma SF, Pendyala S, et al:
Targeting sphingosine kinase 1 attenuates bleomycin-induced
pulmonary fibrosis. FASEB J. 27:1749–1760. 2013. View Article : Google Scholar : PubMed/NCBI
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Mabuchi S, Kuroda H, Takahashi R and
Sasano T: The PI3K/AKT/mTOR pathway as a therapeutic target in
ovarian cancer. Gynecol Oncol. 137:173–179. 2015. View Article : Google Scholar : PubMed/NCBI
|
24
|
Lee SJ, Kim KH and Park KK: Mechanisms of
fibrogenesis in liver cirrhosis: The molecular aspects of
epithelial-mesenchymal transition. World J Hepatol. 6:207–216.
2014. View Article : Google Scholar : PubMed/NCBI
|
25
|
O'Connor JW and Gomez EW: Biomechanics of
TGFβ-induced epithelial-mesenchymal transition: Implications for
fibrosis and cancer. Clin Transl Med. 3:232014. View Article : Google Scholar : PubMed/NCBI
|
26
|
Takano M, Yamamoto C, Yamaguchi K, Kawami
M and Yumoto R: Analysis of TGF-β1- and drug-induced
epithelial-mesenchymal transition in cultured alveolar epithelial
cell line RLE/Abca3. Drug Metab Pharmacokinet. 30:111–118. 2015.
View Article : Google Scholar : PubMed/NCBI
|
27
|
PLOS ONE Staff, . Correction: Melatonin
inhibits endoplasmic reticulum stress and epithelial-mesenchymal
transition during bleomycin-induced pulmonary fibrosis in mice.
PloS One. 10:e01193812015. View Article : Google Scholar : PubMed/NCBI
|
28
|
Zhou N, Lu F, Liu C, Xu K, Huang J, Yu D
and Bi L: IL-8 induces the epithelial-mesenchymal transition of
renal cell carcinoma cells through the activation of AKT signaling.
Oncol Lett. 12:1915–1920. 2016.PubMed/NCBI
|
29
|
Shan B, Man H, Liu J, Wang L, Zhu T, Ma M,
Xv Z, Chen X, Yang X and Li P: TIM-3 promotes the metastasis of
esophageal squamous cell carcinoma by targeting
epithelial-mesenchymal transition via the Akt/GSK-3β/Snail
signaling pathway. Oncol Rep. 36:1551–1561. 2016.PubMed/NCBI
|
30
|
Yi GZ, Liu YW, Xiang W, Wang H, Chen ZY,
Xie SD and Qi ST: Akt and β-catenin contribute to TMZ resistance
and EMT of MGMT negative malignant glioma cell line. J Neurol Sci.
367:101–106. 2016. View Article : Google Scholar : PubMed/NCBI
|