Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)

  • Authors:
    • Kavitha Vijayaraghavan
    • Johanna Rajkumar
    • Syed Nasir Abbas Bukhari
    • Badr Al‑Sayed
    • Mohammed Ali Seyed
  • View Affiliations

  • Published online on: January 19, 2017     https://doi.org/10.3892/mmr.2017.6133
  • Pages: 1007-1016
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Abstract

The study of wound‑healing plants has acquired an interdisciplinary nature with a systematic investigational approach. Several biochemicals are involved in the healing process of the body, including antioxidants and cytokines. Although several pharmaceutical preparations and formulations are available for wound care and management, it remains necessary to search for efficacious treatments, as certain current formulations cause adverse effects or lack efficacy. Phytochemicals or biomarkers from numerous plants suggest they have positive effects on different stages of the wound healing process via various mechanisms. Several herbal medicines have displayed marked activity in the management of wounds and various natural compounds have verified in vivo wound healing potential, and can, therefore, be considered as potential drugs of natural origin. Chromolaena odorata (L.) R.M. King and H. Robinson is considered a tropical weed. However, it exhibits anti‑inflammatory, antipyretic, analgesic, antimicrobial, cytotoxic and numerous other relevant medicinal properties on an appreciable scale, and is known in some parts of the world as a traditional medicine used to treat various ailments. To understand its specific role as nature's gift for healing wounds and its contribution to affordable healthcare, this plant must be scientifically assessed based on the available literature. This review aims to summarize the role of C. odorata and its biomarkers in the wound healing activities of biological systems, which are crucial to its potential future drug design, development and application for the treatment of wounds.
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March-2017
Volume 15 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Vijayaraghavan K, Rajkumar J, Bukhari SN, Al‑Sayed B and Seyed MA: Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review). Mol Med Rep 15: 1007-1016, 2017.
APA
Vijayaraghavan, K., Rajkumar, J., Bukhari, S.N., Al‑Sayed, B., & Seyed, M.A. (2017). Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review). Molecular Medicine Reports, 15, 1007-1016. https://doi.org/10.3892/mmr.2017.6133
MLA
Vijayaraghavan, K., Rajkumar, J., Bukhari, S. N., Al‑Sayed, B., Seyed, M. A."Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)". Molecular Medicine Reports 15.3 (2017): 1007-1016.
Chicago
Vijayaraghavan, K., Rajkumar, J., Bukhari, S. N., Al‑Sayed, B., Seyed, M. A."Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)". Molecular Medicine Reports 15, no. 3 (2017): 1007-1016. https://doi.org/10.3892/mmr.2017.6133