1
|
Medzhitov R: Origin and physiological
roles of inflammation. Nature. 454:428–435. 2008. View Article : Google Scholar : PubMed/NCBI
|
2
|
Maslanik T, Mahaffey L, Tannura K,
Beninson L, Greenwood BN and Fleshner M: The inflammasome and
danger associated molecular patterns (DAMPs) are implicated in
cytokine and chemokine responses following stressor exposure. Brain
Behav Immun. 28:54–62. 2013. View Article : Google Scholar : PubMed/NCBI
|
3
|
Bauer RN, Diaz-Sanchez D and Jaspers I:
Effects of air pollutants on innate immunity: The role of Toll-like
receptors and nucleotide-binding oligomerization domain-like
receptors. J Allergy Clin Immunol. 129:14–26. 2012. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kim YK, Shin JS and Nahm MH: NOD-like
receptors in infection, immunity, and diseases. Yonsei Med J.
57:5–14. 2016. View Article : Google Scholar : PubMed/NCBI
|
5
|
Abderrazak A, Syrovets T, Couchie D, El
Hadri K, Friguet B, Simmet T and Rouis M: NLRP3 inflammasome: From
a danger signal sensor to a regulatory node of oxidative stress and
inflammatory diseases. Redox Biol. 4:296–307. 2015. View Article : Google Scholar : PubMed/NCBI
|
6
|
Elinav E, Strowig T, Kau AL, Henao-Mejia
J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon
JI and Flavell RA: NLRP6 inflammasome regulates colonic microbial
ecology and risk for colitis. Cell. 145:745–757. 2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Brickler T, Gresham K, Meza A,
Coutermarsh-Ott S, Williams TM, Rothschild DE, Allen IC and Theus
MH: Nonessential role for the NLRP1 inflammasome complex in a
murine model of traumatic brain injury. Mediators Inflamm.
2016:63735062016. View Article : Google Scholar : PubMed/NCBI
|
8
|
Tilburgs T, Meissner TB, Ferreira LMR,
Mulder A, Musunuru K, Ye J and Strominger JL: NLRP2 is a suppressor
of NF-κB signaling and HLA-C expression in human trophoblasts†,‡.
Biol Reprod. 96:831–842. 2017. View Article : Google Scholar : PubMed/NCBI
|
9
|
Mahadevan S, Sathappan V, Utama B, Lorenzo
I, Kaskar K and Van den Veyver IB: Maternally expressed NLRP2 links
the subcortical maternal complex (SCMC) to fertility, embryogenesis
and epigenetic reprogramming. Sci Rep. 7:446672017. View Article : Google Scholar : PubMed/NCBI
|
10
|
Peng H, Chang B, Lu C, Su J, Wu Y, Lv P,
Wang Y, Liu J, Zhang B, Quan F, et al: Nlrp2, a maternal effect
gene required for early embryonic development in the mouse. PLoS
One. 7:e303442012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Aird WC: Phenotypic heterogeneity of the
endothelium: I. Structure, function, and mechanisms. Circ Res.
100:158–173. 2007. View Article : Google Scholar : PubMed/NCBI
|
12
|
Kinnunen K, Piippo N, Loukovaara S, Hytti
M, Kaarniranta K and Kauppinen A: Lysosomal destabilization
activates the NLRP3 inflammasome in human umbilical vein
endothelial cells (HUVECs). J Cell Commun Signal. 11:275–279. 2017.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Sun X, Song X, Zhang L, Sun J, Wei X, Meng
L and An J: NLRP2 is highly expressed in a mouse model of ischemic
stroke. Biochem Biophys Res Commun. 479:656–662. 2016. View Article : Google Scholar : PubMed/NCBI
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Santarpia L, Lippman SM and El-Naggar AK:
Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy.
Expert Opin Ther Targets. 16:103–119. 2012. View Article : Google Scholar : PubMed/NCBI
|
16
|
Maurer G, Tarkowski B and Baccarini M: Raf
kinases in cancer-roles and therapeutic opportunities. Oncogene.
30:3477–3488. 2011. View Article : Google Scholar : PubMed/NCBI
|
17
|
McCubrey JA, Steelman LS, Chappell WH,
Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M,
Tafuri A, et al: Roles of the Raf/MEK/ERK pathway in cell growth,
malignant transformation and drug resistance. Biochim Biophys Acta.
1773:1263–1284. 2007. View Article : Google Scholar : PubMed/NCBI
|
18
|
Ozaki E, Campbell M and Doyle SL:
Targeting the NLRP3 inflammasome in chronic inflammatory diseases:
Current perspectives. J Inflamm Res. 8:15–27. 2015.PubMed/NCBI
|
19
|
Vizlin-Hodzic D, Zhai Q, Illes S,
Södersten K, Truvé K, Parris TZ, Sobhan PK, Salmela S, Kosalai ST,
Kanduri C, et al: Early onset of inflammation during ontogeny of
bipolar disorder: The NLRP2 inflammasome gene distinctly
differentiates between patients and healthy controls in the
transition between iPS cell and neural stem cell stages. Transl
Psychiatry. 7:e10102017. View Article : Google Scholar : PubMed/NCBI
|
20
|
Fontalba A, Gutierrez O and Fernandez-Luna
JL: NLRP2, an inhibitor of the NF-kappaB pathway, is
transcriptionally activated by NF-kappaB and exhibits a
nonfunctional allelic variant. J Immunol. 179:8519–8524. 2007.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Aghajanova L, Mahadevan S, Altmäe S,
Stavreus-Evers A, Regan L, Sebire N, Dixon P, Fisher RA and Van den
Veyver IB: No evidence for mutations in NLRP7, NLRP2 or KHDC3L in
women with unexplained recurrent pregnancy loss or infertility. Hum
Reprod. 30:232–238. 2015. View Article : Google Scholar : PubMed/NCBI
|
22
|
Granell M, Urbano-Ispizua A, Pons A,
Aróstegui JI, Gel B, Navarro A, Jansa S, Artells R, Gaya A, Talarn
C, et al: Common variants in NLRP2 and NLRP3 genes are strong
prognostic factors for the outcome of HLA-identical sibling
allogeneic stem cell transplantation. Blood. 112:4337–4342. 2008.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Fragale A, Tartaglia M, Wu J and Gelb BD:
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent
prolonged GAB1 binding and sustained ERK2/MAPK1 activation. Hum
Mutat. 23:267–277. 2004. View Article : Google Scholar : PubMed/NCBI
|
24
|
Apáti A, Jánossy J, Brózik A, Bauer PI and
Magócsi M: Calcium induces cell survival and proliferation through
the activation of the MAPK pathway in a human hormone-dependent
leukemia cell line, TF-1. J Biol Chem. 278:9235–9243. 2003.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Carter BZ, Mak DH, Schober WD,
Cabreira-Hansen M, Beran M, McQueen T, Chen W and Andreeff M:
Regulation of survivin expression through Bcr-Abl/MAPK cascade:
Targeting survivin overcomes imatinib resistance and increases
imatinib sensitivity in imatinib-responsive CML cells. Blood.
107:1555–1563. 2006. View Article : Google Scholar : PubMed/NCBI
|
26
|
Schmid RS, Graff RD, Schaller MD, Chen S,
Schachner M, Hemperly JJ and Maness PF: NCAM stimulates the
Ras-MAPK pathway and CREB phosphorylation in neuronal cells. J
Neurobiol. 38:542–558. 1999. View Article : Google Scholar : PubMed/NCBI
|